Functional subcellular distribution of β1-and β2-adrenergic receptors in rat ventricular cardiac myocytes

Physiological Reports

Volumn 1, Issue 3, 2013, Pages 1-8

  Cros, Caroline ^a   Brette, Fabien ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Calcium; Cardiac myocyte; T tubules; 1 adrenergic receptors; 2 adrenergic receptors

Indexed keywords

EID: 84924076751     PISSN: None     EISSN: 2051817X     Source Type: Journal    
DOI: 10.1002/phy2.38     Document Type: Article

References (26)

1. Balijepalli, R. C., J. D. Foell, D. D. Hall, J. W. Hell, and T. J. Kamp. 2006. Localization of cardiac L-type Ca2+ channels to a caveolar macromolecular signaling complex is required for β2-adrenergic regulation. Proc. Natl. Acad. Sci. USA 103:7500–7505.
2. Bers, D. M. 2002. Cardiac excitation-contraction coupling. Nature 415:198–205.
3. Brette, F., and C. Orchard. 2003. T-tubule function in mammalian cardiac myocytes. Circ. Res. 92:1182–1192.
4. Brette, F., and C. H. Orchard. 2006. Density and sub-cellular distribution of cardiac and neuronal sodium channel isoforms in rat ventricular myocytes. Biochem. Biophys. Res. Commun. 348:1163–1166.
5. Brette, F., K. Komukai, and C. H. Orchard. 2002. Validation of formamide as a detubulation agent in isolated rat cardiac cells. Am. J. Physiol. Heart Circ. Physiol. 283: H1720–H1728.
6. Brette, F., P. Rodriguez, K. Komukai, J. Colyer, and C. H. Orchard. 2004. beta-adrenergic stimulation restores the Ca transient of ventricular myocytes lacking t-tubules. J. Mol. Cell. Cardiol. 36:265–275.
7. Calaghan, S., and E. White. 2006. Caveolae modulate excitation-contraction coupling and beta2-adrenergic signalling in adult rat ventricular myocytes. Cardiovasc. Res. 69:816–824.
8. Chase, A., and C. H. Orchard. 2011. Ca efflux via the sarcolemmal Ca ATPase occurs only in the t-tubules of rat ventricular myocytes. J. Mol. Cell. Cardiol. 50:187–193.
9. Chase, A., J. Colyer, and C. H. Orchard. 2010. Localised Ca channel phosphorylation modulates the distribution of L-type Ca current in cardiac myocytes. J. Mol. Cell. Cardiol. 49:121–131.
10. Despa, S., F. Brette, C. H. Orchard, and D. M. Bers. 2003. Na/Ca exchange and Na/K-ATPase function are equally concentrated in transverse tubules of rat ventricular myocytes. Biophys. J. 85:3388–3396.
11. Fischmeister, R., L. R. Castro, A. bi-Gerges, F. Rochais, J. Jurevicius, J. Leroy, et al. 2006. Compartmentation of cyclic nucleotide signaling in the heart: the role of cyclic nucleotide phosphodiesterases. Circ. Res. 99:816–828.
12. Harvey, R. D., and S. C. Calaghan. 2012. Caveolae create local signalling domains through their distinct protein content, lipid profile and morphology. J. Mol. Cell. Cardiol. 52: 366–375.
13. He, J. Q., R. C. Balijepalli, R. A. Haworth, and T. J. Kamp. 2005. Crosstalk of beta-adrenergic receptor subtypes through Gi blunts beta-adrenergic stimulation of L-type Ca2+ channels in canine heart failure. Circ. Res. 97: 566–573.
14. Hohl, C. M., and Q. A. Li. 1991. Compartmentation of cAMP in adult canine ventricular myocytes. Relation to single-cell free Ca2+ transients. Circ. Res. 69:1369–1379.
15. Hussain, M., and C. H. Orchard. 1997. Sarcoplasmic reticulum Ca2 + content, L-type Ca2+ current and the Ca2+ transient in rat myocytes during beta-adrenergic stimulation. J. Physiol. 505:385–402.
16. Kuschel, M., Y. Y. Zhou, H. Cheng, S. J. Zhang, Y. Chen, E. G. Lakatta, et al. 1999. G(i) protein-mediated functional compartmentalization of cardiac beta(2)-adrenergic signaling. J. Biol. Chem. 274:22048–22052.
17. Nikolaev, V. O., A. Moshkov, A. R. Lyon, M. Miragoli, P. Novak, H. Paur, et al. 2010. Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation. Science 327:1653–1657.
18. Pasek, M., F. Brette, A. Nelson, C. Pearce, A. Qaiser, G. Christe, et al. 2008. Quantification of t-tubule area and protein distribution in rat cardiac ventricular myocytes. Prog. Biophys. Mol. Biol. 96:244–257.
19. Smyrnias, I., W. Mair, D. Harzheim, S. A. Walker, H. L. Roderick, and M. D. Bootman. 2010. Comparison of the T-tubule system in adult rat ventricular and atrial myocytes, and its role in excitation-contraction coupling and inotropic stimulation. Cell Calcium 47:210–223.
20. Steadman, BW, KB Moore, KW Spitzer, and JH Bridge 1988. A video system for measuring motion in contracting heart cells-1. IEEE Trans. Biomed. Eng. 35:264–272.
21. Steinberg, S. F., and L. L. Brunton. 2001. Compartmentation of G protein-coupled signaling pathways in cardiac myocytes. Annu. Rev. Pharmacol. Toxicol. 41:751–773.
22. Trafford, A. W., M. E. Diaz, N. Negretti, and D. A. Eisner. 1997. Enhanced Ca2+ current and decreased Ca2+ efflux restore sarcoplasmic reticulum Ca2+ content after depletion. Circ. Res. 81:477–484.
23. Xiang, Y. K. 2011. Compartmentalization of beta-adrenergic signals in cardiomyocytes. Circ. Res. 109:231–244.
24. Zaccolo, M., and T. Pozzan. 2002. Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes. Science 295:1711–1715.
25. Zhou, Y. Y., D. Yang, W. Z. Zhu, S. J. Zhang, D. J. Wang, D. K. Rohrer, et al. 2000. Spontaneous activation of beta(2)-but not beta(1)-adrenoceptors expressed in cardiac myocytes from beta(1) beta(2) double knockout mice. Mol. Pharmacol. 58:887–894.
26. Zhou, P., Y. T. Zhao, Y. B. Guo, S. M. Xu, S. H. Bai, E. G. Lakatta, et al. 2009. Beta-adrenergic signaling accelerates and synchronizes cardiac ryanodine receptor response to a single L-type Ca2+ channel. Proc. Natl. Acad. Sci. USA 106:18028–18033.