Na/Ca Exchange and Na/K-ATPase Function Are Equally Concentrated in Transverse Tubules of Rat Ventricular Myocytes

Biophysical Journal

Volumn 85, Issue 5, 2003, Pages 3388-3396

  Despa, S ^a   Brette, F ^b   Orchard, C H ^b   Bers, Donald M ^a,c  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CALCIUM ION; FORMAMIDE; POTASSIUM ION; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM ION;

ANIMAL CELL; ARTICLE; CELL VOLUME; CONTROLLED STUDY; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE; HEART VENTRICLE WALL; ION EXCHANGE; NONHUMAN; POTASSIUM CURRENT; RAT; SODIUM CALCIUM EXCHANGE; TRANSVERSE TUBULAR SYSTEM;

ANIMALIA;

EID: 0242290781     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(03)74758-4     Document Type: Article

References (28)

1. Bers, D. M. 2001. Excitation-contraction coupling and cardiac contractile force. Kluwer Academic Publishers, Dordrecht, The Netherlands.
2. + regulation in cardiac myocytes. Cardiovasc. Res. 57:897-912.
3. Blanco, G., and R. W. Mercer. 1998. Isozymes of the Na-K-ATPase: heterogeneity in structure, diversity in function. Am. J. Physiol. 275: F633-F650.
4. Boyett, M., J. E. Frampton, and M. S. Kirby. 1991. The length, width and volume of isolated rat and ferret ventricular myocytes during twitch contractions and change in osmotic strength. Exp. Physiol. 76:259-270.
5. Brette F., K. Komukai, and C. H. Orchard. 2002. Validation of formamide as a detubulation agent in isolated rat cardiac cells. Am. J. Physiol. 283:H1720-H1728.
6. Carl, S. L., K. Felix, A. H. Caswell, N. R. Brandt, W. J. Ball, Jr., P. L. Vaghy, G. Meissner, and D. G. Ferguson. 1995. Immunolocalization of sarcolemmal dihydropyridine receptor and sarcoplasmic reticular triadin and ryanodine receptor in rabbit ventricle and atrium. J. Cell Biol. 129:672-682.
7. Cordeiro, J. M., K. W. Spitzer, W. R. Giles, P. E. Ershler, M. B. Cannell, and J. H. Bridge. 2001. Location of the initiation site of calcium transients and sparks in rabbit heart Purkinje cells. J. Physiol. 531:301-314.
8. + pump rate in rat and rabbit ventricular myocytes. J. Physiol. 539:133-143.
9. i depletion and Na buffering. Biophys. J. 84:4157-4166.
10. 2+ exchange protein in mammalian cardiac myocytes: an immunofluorescence and immunocolloidal gold-labeling study. J. Cell Biol. 117:337-345.
11. i in a restricted space of guinea-pig ventricular cells. J. Physiol. 509:457-470.
12. i gradients during excitation-contraction coupling in newborn rabbit ventricular myocytes. Circ. Res. 85:415-427.
13. 2+ exchange in giant excised sarcolemmal membrane patches. Nature. 344:242-245.
14. Huser, J., S. L. Lipsius, and L. A. Blatter. 1996. Calcium gradients during excitation-contraction coupling in cat atrial myocytes. J. Physiol. 494:641-651.
15. Kawai, M., M. Hussain, and C. H. Orchard. 1999. Excitation-contraction coupling in rat ventricular myocytes after formamide-induced detubulation. Am. J. Physiol. 277:H603-H609.
16. Kieval, R. S., R. J. Bloch, G. E. Lindenmayer, A. Ambesi, and W. J. Lederer. 1992. Immunofluorescence localization of the Na-Ca exchanger in heart cells. Am. J. Physiol. 263:C545-C550.
17. Kim, A. M., and J. L. Vergara. 1998. Supercharging accelerates t-tubule membrane potential changes in voltage clamped frog skeletal muscle fibers. Biophys. J. 75:2098-2116.
18. McDonough, A. A., Y. Zhang, V. Shin, and J. S. Frank. 1996. Subcellular distribution of Na pump isoform subunits in mammalian cardiac myocytes. Am. J. Physiol. 270:C1221-C1227.
19. + pump and sarcoplasmic reticulum in smooth muscle. Nature. 365:657-660.
20. Page, E. 1978. Quantitative ultrastructural analysis in cardiac membrane physiology. Am. J. Physiol. 235:C147-C158.
21. Page, E., L. P. McCallister, and B. Power. 1971. Stereological measurements of cardiac ultrastructures implicated in excitation-contraction coupling. Proc. Natl. Acad. Sci. USA. 68:1465-1466.
22. Page, E., and M. Surdyk-Droske. 1979. Distribution, surface density, and membrane area of diadic junctional contacts between plasma membrane and terminal cisterns in mammalian ventricle. Circ. Res. 45:260-267.
23. Scriven, D. R., P. Dan, and E. D. Moore. 2000. Distribution of proteins implicated in excitation-contraction coupling in rat ventricular myocytes. Biophys. J. 79:2682-2691.
24. Soeller, C., and M. B. Cannell. 1999. Examination of the transverse tubular system in living cardiac rat myocytes by 2-photon microscopy and digital image-processing techniques. Cric. Res. 84:266-275.
25. 2+ exchanger-mediated relaxation in rabbit ventricular myocytes. J. Physiol. 533:165-173.
26. Trafford, A. W., M. E. Diaz, S. C. O'Neill, and D. A. Eisner. 1995. Comparison of subsarcolemmal and bulk calcium concentration during spontaneous calcium release in rat ventricular myocytes. J. Physiol. 488:577-586.
27. Weber, C. R., V. Piacentino III, K. S. Ginsburg, S. R Houser, and D. M. Bers. 2002. Na/Ca exchange current and submembrane [Ca] during the cardiac action potential. Circ. Res. 90:182-189.
28. 2+ exchange activity is localized in the t-tubules of rat ventricular myocytes. Circ. Res. 91:315-322.