The hypoxia-induced microRNA-130a controls pulmonary smooth muscle cell proliferation by directly targeting CDKN1A

International Journal of Biochemistry and Cell Biology

Volumn 61, Issue , 2015, Pages 129-137

  Brock, Matthias ^a,b   Haider, Thomas J ^b   Vogel, Johannes ^b   Gassmann, Max ^b   Speich, Rudolf ^a   Trenkmann, Michelle ^a   Ulrich, Silvia ^a   Kohler, Malcolm ^a   Huber, Lars C ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Hypoxia; MicroRNA; Proliferation; Pulmonary hypertension; Vascular remodelinga

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1A; MICRORNA; MICRORNA 130A; MICRORNA 301A; UNCLASSIFIED DRUG; CDKN1A PROTEIN, HUMAN; CDKN1A PROTEIN, MOUSE; MIRN130 MICRORNA, HUMAN; MIRN130 MICRORNA, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL HYPOXIA; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; HEART LEFT VENTRICLE VOLUME; HEART RIGHT VENTRICLE HYPERTROPHY; HEK293 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; POINT MUTATION; PULMONARY ARTERY; PULMONARY ARTERY SMOOTH MUSCLE CELL; PULMONARY HYPERTENSION; REPORTER GENE; RNA DEGRADATION; SMOOTH MUSCLE FIBER; VASCULAR REMODELING; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CYTOLOGY; DISEASE MODEL; GENETICS; HEART VENTRICLE REMODELING; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ANIMALS; CELL HYPOXIA; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DISEASE MODELS, ANIMAL; HEK293 CELLS; HUMANS; HYPERTENSION, PULMONARY; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; MYOCYTES, SMOOTH MUSCLE; VASCULAR REMODELING; VENTRICULAR REMODELING;

EID: 84923934273     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2015.02.002     Document Type: Article

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