메뉴 건너뛰기




Volumn 26, Issue 2, 2015, Pages 314-327

GIV/Girdin links vascular endothelial growth factor signaling to Akt survival signaling in podocytes independent of nephrin

Author keywords

[No Author keywords available]

Indexed keywords

G ALPHA INTERACTING VESICLE ASSOCIATED PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; MEMBRANE PROTEIN; NEPHRIN; PROTEIN KINASE B; PROTEIN KINASE B BETA; PUROMYCIN AMINONUCLEOSIDE; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2; ACTIN BINDING PROTEIN; GALPHA-INTERACTING, VESICLE-ASSOCIATED PROTEIN, RAT; GNAI3 PROTEIN, RAT; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; SIGNAL PEPTIDE; TARGET OF RAPAMYCIN KINASE; VASCULOTROPIN A;

EID: 84923931859     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2013090985     Document Type: Article
Times cited : (42)

References (70)
  • 1
    • 84857243208 scopus 로고    scopus 로고
    • Cell biology and pathology of podocytes
    • Greka A, Mundel P: Cell biology and pathology of podocytes. Annu Rev Physiol 74: 299-323, 2012
    • (2012) Annu Rev Physiol , vol.74 , pp. 299-323
    • Greka, A.1    Mundel, P.2
  • 2
    • 0037207471 scopus 로고    scopus 로고
    • Cell biology of the glomerular podocyte
    • Pavenstädt H, Kriz W, Kretzler M: Cell biology of the glomerular podocyte. Physiol Rev 83: 253-307, 2003
    • (2003) Physiol Rev , vol.83 , pp. 253-307
    • Pavenstädt, H.1    Kriz, W.2    Kretzler, M.3
  • 3
    • 84859838187 scopus 로고    scopus 로고
    • Podocytes: Gaining a foothold
    • Garg P, Holzman LB: Podocytes: Gaining a foothold. Exp Cell Res 318: 955-963, 2012
    • (2012) Exp Cell Res , vol.318 , pp. 955-963
    • Garg, P.1    Holzman, L.B.2
  • 4
    • 0035210580 scopus 로고    scopus 로고
    • Caught flat-footed: Podocyte damage and the molecular bases of focal glomerulosclerosis
    • Kerjaschki D: Caught flat-footed: Podocyte damage and the molecular bases of focal glomerulosclerosis. J Clin Invest 108: 1583-1587, 2001
    • (2001) J Clin Invest , vol.108 , pp. 1583-1587
    • Kerjaschki, D.1
  • 5
    • 84873025518 scopus 로고    scopus 로고
    • Podocyte biology and pathogenesis of kidney disease
    • Reiser J, Sever S: Podocyte biology and pathogenesis of kidney disease. Annu Rev Med 64: 357-366, 2013
    • (2013) Annu Rev Med , vol.64 , pp. 357-366
    • Reiser, J.1    Sever, S.2
  • 6
    • 0037093320 scopus 로고    scopus 로고
    • Podocyte is the major culprit accounting for the progression of chronic renal disease
    • Kriz W: Podocyte is the major culprit accounting for the progression of chronic renal disease. Microsc Res Tech 57: 189-195, 2002
    • (2002) Microsc Res Tech , vol.57 , pp. 189-195
    • Kriz, W.1
  • 7
    • 34250006557 scopus 로고    scopus 로고
    • The spectrum of podocytopathies: A unifying view of glomerular diseases
    • Wiggins RC: The spectrum of podocytopathies: A unifying view of glomerular diseases. Kidney Int 71: 1205-1214, 2007
    • (2007) Kidney Int , vol.71 , pp. 1205-1214
    • Wiggins, R.C.1
  • 8
    • 33745058119 scopus 로고    scopus 로고
    • The podocyte's response to injury: Role in proteinuria and glomerulosclerosis
    • Shankland SJ: The podocyte's response to injury: Role in proteinuria and glomerulosclerosis. Kidney Int 69: 2131-2147, 2006
    • (2006) Kidney Int , vol.69 , pp. 2131-2147
    • Shankland, S.J.1
  • 10
    • 18844411833 scopus 로고    scopus 로고
    • The slit diaphragm: A signaling platform to regulate podocyte function
    • Huber TB, Benzing T: The slit diaphragm: A signaling platform to regulate podocyte function. Curr Opin Nephrol Hypertens 14: 211-216, 2005
    • (2005) Curr Opin Nephrol Hypertens , vol.14 , pp. 211-216
    • Huber, T.B.1    Benzing, T.2
  • 12
    • 39349104907 scopus 로고    scopus 로고
    • Nephrin mediates actin reorganization via phosphoinositide 3-kinase in podocytes
    • Zhu J, Sun N, Aoudjit L, Li H, Kawachi H, Lemay S, Takano T: Nephrin mediates actin reorganization via phosphoinositide 3-kinase in podocytes. Kidney Int 73: 556-566, 2008
    • (2008) Kidney Int , vol.73 , pp. 556-566
    • Zhu, J.1    Sun, N.2    Aoudjit, L.3    Li, H.4    Kawachi, H.5    Lemay, S.6    Takano, T.7
  • 18
    • 0033921768 scopus 로고    scopus 로고
    • The urinary podocyte as a marker for the differential diagnosis of idiopathic focal glomerulosclerosis and minimal-change nephrotic syndrome
    • Nakamura T, Ushiyama C, Suzuki S, Hara M, Shimada N, Ebihara I, Koide H: The urinary podocyte as a marker for the differential diagnosis of idiopathic focal glomerulosclerosis and minimal-change nephrotic syndrome. Am J Nephrol 20: 175-179, 2000
    • (2000) Am J Nephrol , vol.20 , pp. 175-179
    • Nakamura, T.1    Ushiyama, C.2    Suzuki, S.3    Hara, M.4    Shimada, N.5    Ebihara, I.6    Koide, H.7
  • 19
    • 81755184481 scopus 로고    scopus 로고
    • Upregulation of nestin protects podocytes from apoptosis induced by puromycin aminonucleoside
    • Wen D, You L, Zhang Q, Zhang L, Gu Y, Hao CM, Chen J: Upregulation of nestin protects podocytes from apoptosis induced by puromycin aminonucleoside. Am J Nephrol 34: 423-434, 2011
    • (2011) Am J Nephrol , vol.34 , pp. 423-434
    • Wen, D.1    You, L.2    Zhang, Q.3    Zhang, L.4    Gu, Y.5    Hao, C.M.6    Chen, J.7
  • 21
    • 2442707596 scopus 로고    scopus 로고
    • The role of vascular endothelial growth factor (VEGF) in renal pathophysiology
    • Schrijvers BF, Flyvbjerg A, De Vriese AS: The role of vascular endothelial growth factor (VEGF) in renal pathophysiology. Kidney Int 65: 2003-2017, 2004
    • (2004) Kidney Int , vol.65 , pp. 2003-2017
    • Schrijvers, B.F.1    Flyvbjerg, A.2    De Vriese, A.S.3
  • 22
    • 84865709126 scopus 로고    scopus 로고
    • VEGF and podocytes in diabetic nephropathy
    • Tufro A, Veron D: VEGF and podocytes in diabetic nephropathy. Semin Nephrol 32: 385-393, 2012
    • (2012) Semin Nephrol , vol.32 , pp. 385-393
    • Tufro, A.1    Veron, D.2
  • 25
    • 0032888010 scopus 로고    scopus 로고
    • Vascular endothelial growth factor mRNA expression in minimal change, membranous, and diabetic nephropathy demonstrated by non-isotopic in situ hybridisation
    • Bailey E, Bottomley MJ, Westwell S, Pringle JH, Furness PN, Feehally J, Brenchley PE, Harper SJ: Vascular endothelial growth factor mRNA expression in minimal change, membranous, and diabetic nephropathy demonstrated by non-isotopic in situ hybridisation. J Clin Pathol 52: 735-738, 1999
    • (1999) J Clin Pathol , vol.52 , pp. 735-738
    • Bailey, E.1    Bottomley, M.J.2    Westwell, S.3    Pringle, J.H.4    Furness, P.N.5    Feehally, J.6    Brenchley, P.E.7    Harper, S.J.8
  • 26
    • 84923864792 scopus 로고    scopus 로고
    • Relevance of VEGF and nephrin expression in glomerular diseases
    • Bertuccio CA: Relevance of VEGF and nephrin expression in glomerular diseases. J Signal Transduct 2011: 718609, 2011
    • (2011) J Signal Transduct , vol.2011 , pp. 718609
    • Bertuccio, C.A.1
  • 28
    • 85046980000 scopus 로고    scopus 로고
    • GIV/Girdin is a rheostat that fi ne-tunes growth factor signals during tumor progression
    • Ghosh P, Garcia-Marcos M, Farquhar MG: GIV/Girdin is a rheostat that fi ne-tunes growth factor signals during tumor progression. Cell Adhes Migr 5: 237-248, 2011
    • (2011) Cell Adhes Migr , vol.5 , pp. 237-248
    • Ghosh, P.1    Garcia-Marcos, M.2    Farquhar, M.G.3
  • 30
    • 80053257932 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the Gα-interacting protein GIV promotes activation of phosphoinositide 3-kinase during cell migration
    • Lin C, Ear J, Pavlova Y, Mittal Y, Kufareva I, Ghassemian M, Abagyan R, Garcia-Marcos M, Ghosh P: Tyrosine phosphorylation of the Gα-interacting protein GIV promotes activation of phosphoinositide 3-kinase during cell migration. Sci Signal 4: ra64, 2011
    • (2011) Sci Signal , vol.4 , pp. ra64
    • Lin, C.1    Ear, J.2    Pavlova, Y.3    Mittal, Y.4    Kufareva, I.5    Ghassemian, M.6    Abagyan, R.7    Garcia-Marcos, M.8    Ghosh, P.9
  • 31
    • 84893437204 scopus 로고    scopus 로고
    • Novel insights into G protein and G protein-coupled receptor signaling in cancer
    • O'Hayre M, Degese MS, Gutkind JS: Novel insights into G protein and G protein-coupled receptor signaling in cancer. Curr Opin Cell Biol 27: 126-135, 2014
    • (2014) Curr Opin Cell Biol , vol.27 , pp. 126-135
    • O'Hayre, M.1    Degese, M.S.2    Gutkind, J.S.3
  • 33
    • 0021262325 scopus 로고
    • Identification and characterization of podocalyxin - The major sialoprotein of the renal glomerular epithelial cell
    • Kerjaschki D, Sharkey DJ, Farquhar MG: Identification and characterization of podocalyxin - the major sialoprotein of the renal glomerular epithelial cell. J Cell Biol 98: 1591-1596, 1984
    • (1984) J Cell Biol , vol.98 , pp. 1591-1596
    • Kerjaschki, D.1    Sharkey, D.J.2    Farquhar, M.G.3
  • 35
    • 0024209817 scopus 로고
    • Ultrastructural organization of contractile and cytoskeletal proteins in glomerular podocytes of chicken, rat, and man
    • Drenckhahn D, Franke RP: Ultrastructural organization of contractile and cytoskeletal proteins in glomerular podocytes of chicken, rat, and man. Lab Invest 59: 673-682, 1988
    • (1988) Lab Invest , vol.59 , pp. 673-682
    • Drenckhahn, D.1    Franke, R.P.2
  • 38
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • Sarbassov DD, Guertin DA, Ali SM, Sabatini DM: Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307: 1098-1101, 2005
    • (2005) Science , vol.307 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 39
    • 84859778293 scopus 로고    scopus 로고
    • mTOR signaling in growth control and disease
    • Laplante M, Sabatini DM: mTOR signaling in growth control and disease. Cell 149: 274-293, 2012
    • (2012) Cell , vol.149 , pp. 274-293
    • Laplante, M.1    Sabatini, D.M.2
  • 40
    • 58649092475 scopus 로고    scopus 로고
    • mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)
    • García-Martínez JM, Alessi DR: mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1). Biochem J 416: 375-385, 2008
    • (2008) Biochem J , vol.416 , pp. 375-385
    • García-Martínez, J.M.1    Alessi, D.R.2
  • 41
    • 84893842033 scopus 로고    scopus 로고
    • mTOR controls kidney epithelia in health and disease
    • Grahammer F, Wanner N, Huber TB:mTOR controls kidney epithelia in health and disease. Nephrol Dial Transplant 29[Suppl 1]: i9-i18, 2014
    • (2014) Nephrol Dial Transplant , vol.29 , pp. i9-i18
    • Grahammer, F.1    Wanner, N.2    Huber, T.B.3
  • 43
    • 62549124627 scopus 로고    scopus 로고
    • GIV is a nonreceptor GEF for G alpha i with a unique motif that regulates Akt signaling
    • Garcia-Marcos M, Ghosh P, Farquhar MG: GIV is a nonreceptor GEF for G alpha i with a unique motif that regulates Akt signaling. Proc Natl Acad Sci U S A 106: 3178-3183, 2009
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3178-3183
    • Garcia-Marcos, M.1    Ghosh, P.2    Farquhar, M.G.3
  • 44
    • 0028355624 scopus 로고
    • Crystallization and preliminary crystallographic studies of Gi alpha 1 and mutants of Gi alpha 1 in the GTP and GDP-bound states
    • Coleman DE, Lee E, Mixon MB, Linder ME, Berghuis AM, Gilman AG, Sprang SR: Crystallization and preliminary crystallographic studies of Gi alpha 1 and mutants of Gi alpha 1 in the GTP and GDP-bound states. J Mol Biol 238: 630-634, 1994
    • (1994) J Mol Biol , vol.238 , pp. 630-634
    • Coleman, D.E.1    Lee, E.2    Mixon, M.B.3    Linder, M.E.4    Berghuis, A.M.5    Gilman, A.G.6    Sprang, S.R.7
  • 47
    • 48249106623 scopus 로고    scopus 로고
    • Activation of Galphai3 triggers cell migration via regulation of GIV
    • Ghosh P, Garcia-Marcos M, Bornheimer SJ, Farquhar MG: Activation of Galphai3 triggers cell migration via regulation of GIV. J Cell Biol 182: 381-393, 2008
    • (2008) J Cell Biol , vol.182 , pp. 381-393
    • Ghosh, P.1    Garcia-Marcos, M.2    Bornheimer, S.J.3    Farquhar, M.G.4
  • 48
    • 67149093390 scopus 로고    scopus 로고
    • Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein
    • Eguchi A, Meade BR, Chang YC, Fredrickson CT, Willert K, Puri N, Dowdy SF: Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein. Nat Biotechnol, 27: 567-571, 2009
    • (2009) Nat Biotechnol , vol.27 , pp. 567-571
    • Eguchi, A.1    Meade, B.R.2    Chang, Y.C.3    Fredrickson, C.T.4    Willert, K.5    Puri, N.6    Dowdy, S.F.7
  • 50
    • 79952343266 scopus 로고    scopus 로고
    • A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals
    • Garcia-Marcos M, Ear J, Farquhar MG, Ghosh P: A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals. Mol Biol Cell 22: 673-686, 2011
    • (2011) Mol Biol Cell , vol.22 , pp. 673-686
    • Garcia-Marcos, M.1    Ear, J.2    Farquhar, M.G.3    Ghosh, P.4
  • 51
    • 80052774779 scopus 로고    scopus 로고
    • Src homology domain 2-containing protein-tyrosine phosphatase-1 (SHP-1) binds and dephosphorylates G(alpha)-interacting, vesicle-associated protein (GIV)/Girdin and attenuates the GIV-phosphatidylinositol 3-kinase (PI3K)-Akt signaling pathway
    • Mittal Y, Pavlova Y, Garcia-Marcos M, Ghosh P: Src homology domain 2-containing protein-tyrosine phosphatase-1 (SHP-1) binds and dephosphorylates G(alpha)-interacting, vesicle-associated protein (GIV)/Girdin and attenuates the GIV-phosphatidylinositol 3-kinase (PI3K)-Akt signaling pathway. J Biol Chem 286: 32404-32415, 2011
    • (2011) J Biol Chem , vol.286 , pp. 32404-32415
    • Mittal, Y.1    Pavlova, Y.2    Garcia-Marcos, M.3    Ghosh, P.4
  • 52
    • 81155123707 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor 2 direct interaction with nephrin links VEGF-A signals to actin in kidney podocytes
    • Bertuccio C, Veron D, Aggarwal PK, Holzman L, Tufro A: Vascular endothelial growth factor receptor 2 direct interaction with nephrin links VEGF-A signals to actin in kidney podocytes. J Biol Chem 286: 39933-39944, 2011
    • (2011) J Biol Chem , vol.286 , pp. 39933-39944
    • Bertuccio, C.1    Veron, D.2    Aggarwal, P.K.3    Holzman, L.4    Tufro, A.5
  • 53
    • 0034954343 scopus 로고    scopus 로고
    • Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton
    • Takeda T, McQuistan T, Orlando RA, Farquhar MG: Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton. J Clin Invest 108: 289-301, 2001
    • (2001) J Clin Invest , vol.108 , pp. 289-301
    • Takeda, T.1    McQuistan, T.2    Orlando, R.A.3    Farquhar, M.G.4
  • 55
    • 84856786346 scopus 로고    scopus 로고
    • Nephrotic syndrome unfavorable course correlates with down-regulation of podocyte vascular endothelial growth factor receptor (VEGFR)-2
    • Ostalska-Nowicka D, Malinska A, Zabel M, Witkiewicz W, Nowicki M: Nephrotic syndrome unfavorable course correlates with down-regulation of podocyte vascular endothelial growth factor receptor (VEGFR)-2. Folia Histochem Cytobiol 49: 472-478, 2011
    • (2011) Folia Histochem Cytobiol , vol.49 , pp. 472-478
    • Ostalska-Nowicka, D.1    Malinska, A.2    Zabel, M.3    Witkiewicz, W.4    Nowicki, M.5
  • 58
    • 12344309059 scopus 로고    scopus 로고
    • Autocrine and paracrine functions of vascular endothelial growth factor (VEGF) in renal tubular epithelial cells
    • Villegas G, Lange-Sperandio B, Tufro A: Autocrine and paracrine functions of vascular endothelial growth factor (VEGF) in renal tubular epithelial cells. Kidney Int 67: 449-457, 2005
    • (2005) Kidney Int , vol.67 , pp. 449-457
    • Villegas, G.1    Lange-Sperandio, B.2    Tufro, A.3
  • 59
    • 27744446645 scopus 로고    scopus 로고
    • Statins prevent oxidized LDL-induced injury of glomerular podocytes by activating the phosphatidylinositol 3-kinase/AKT-signaling pathway
    • Bussolati B, Deregibus MC, Fonsato V, Doublier S, Spatola T, Procida S, Di Carlo F, Camussi G: Statins prevent oxidized LDL-induced injury of glomerular podocytes by activating the phosphatidylinositol 3-kinase/AKT-signaling pathway. J Am Soc Nephrol 16: 1936-1947, 2005
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1936-1947
    • Bussolati, B.1    Deregibus, M.C.2    Fonsato, V.3    Doublier, S.4    Spatola, T.5    Procida, S.6    Di Carlo, F.7    Camussi, G.8
  • 61
    • 20444472383 scopus 로고    scopus 로고
    • Identification and characterization of GIV, a novel Galpha i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles
    • Le-Niculescu H, Niesman I, Fischer T, DeVries L, Farquhar MG: Identification and characterization of GIV, a novel Galpha i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles. J Biol Chem 280: 22012-22020, 2005
    • (2005) J Biol Chem , vol.280 , pp. 22012-22020
    • Le-Niculescu, H.1    Niesman, I.2    Fischer, T.3    DeVries, L.4    Farquhar, M.G.5
  • 62
    • 4344565772 scopus 로고    scopus 로고
    • Nephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrin
    • Lehtonen S, Lehtonen E, Kudlicka K, Holthöfer H, Farquhar MG: Nephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrin. Am J Pathol 165: 923-936, 2004
    • (2004) Am J Pathol , vol.165 , pp. 923-936
    • Lehtonen, S.1    Lehtonen, E.2    Kudlicka, K.3    Holthöfer, H.4    Farquhar, M.G.5
  • 64
    • 0031563832 scopus 로고    scopus 로고
    • Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalizedmouse podocyte cell lines
    • Mundel P, Reiser J, Zúñiga Mejía Borja A, Pavenstädt H, Davidson GR, Kriz W, Zeller R: Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalizedmouse podocyte cell lines. Exp Cell Res 236: 248-258, 1997
    • (1997) Exp Cell Res , vol.236 , pp. 248-258
    • Mundel, P.1    Reiser, J.2    Zúñiga Mejía Borja, A.3    Pavenstädt, H.4    Davidson, G.R.5    Kriz, W.6    Zeller, R.7
  • 65
    • 0029088005 scopus 로고
    • Localization of GTPases by indirect immunofluorescence and immunoelectron microscopy
    • McCaffery JM, Farquhar MG: Localization of GTPases by indirect immunofluorescence and immunoelectron microscopy. Methods Enzymol 257: 259-279, 1995
    • (1995) Methods Enzymol , vol.257 , pp. 259-279
    • McCaffery, J.M.1    Farquhar, M.G.2
  • 66
    • 0025001684 scopus 로고
    • Monoclonal antibodies against membrane proteins of the rat glomerulus. Immunochemical specificity and immuno fluorescence distribution of the antigens
    • Miettinen A, Dekan G, Farquhar MG: Monoclonal antibodies against membrane proteins of the rat glomerulus. Immunochemical specificity and immuno fluorescence distribution of the antigens. Am J Pathol 137: 929-944, 1990
    • (1990) Am J Pathol , vol.137 , pp. 929-944
    • Miettinen, A.1    Dekan, G.2    Farquhar, M.G.3
  • 67
    • 77951248135 scopus 로고    scopus 로고
    • A structural determinant that renders G alpha(i) sensitive to activation by GIV/girdin is required to promote cell migration
    • Garcia-Marcos M, Ghosh P, Ear J, Farquhar MG: A structural determinant that renders G alpha(i) sensitive to activation by GIV/girdin is required to promote cell migration. J Biol Chem 285: 12765-12777, 2010
    • (2010) J Biol Chem , vol.285 , pp. 12765-12777
    • Garcia-Marcos, M.1    Ghosh, P.2    Ear, J.3    Farquhar, M.G.4
  • 69
    • 79957815267 scopus 로고    scopus 로고
    • Peroxisomeproliferator-activated receptor-a is renoprotective in doxorubicin-induced glomerular injury
    • Zhou Y, Kong X, Zhao P, Yang H, Chen L, Miao J, Zhang X, Yang J, Ding J, Guan Y: Peroxisomeproliferator-activated receptor-a is renoprotective in doxorubicin-induced glomerular injury. Kidney Int 79: 1302-1311, 2011
    • (2011) Kidney Int , vol.79 , pp. 1302-1311
    • Zhou, Y.1    Kong, X.2    Zhao, P.3    Yang, H.4    Chen, L.5    Miao, J.6    Zhang, X.7    Yang, J.8    Ding, J.9    Guan, Y.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.