Prospective study directed to the synthesis of unsymmetrical linked bis-5-arylidene rhodanine derivatives via "one-pot two steps" reactions under microwave irradiation with their antitumor activity

Medicinal Chemistry Research

Volumn 24, Issue 4, 2015, Pages 1653-1661

  Coulibaly, Wacothon Karime ^a,b,d   Paquin, Ludovic ^a   Bénie, Anoubilé ^b   Békro, Yves Alain ^b   Le Guével, Rémy ^c   Ravache, Myriam ^c   Corlu, Anne ^c   Bazureau, Jean Pierre ^a  

^a INSTITUT DES SCIENCES CHIMIQUES DE RENNES   (France)

^b UNIVERSITÉ NANGUI ABROGOUA   (Côte d’Ivoire)

^c UNIVERSITÉ DE RENNES 1   (France)

^d Institut de Gestion Agropastorale   (Côte d’Ivoire)

Author keywords

5 Arylidene 2 thioxo 1,3 thiazolidine 4 one; Knoevenagel condensation; Microwave; Rhodanine; Tumoral lines; Unsymmetrical bis rhodanine

Indexed keywords

3 (2 AMINOETHYL) 5 (1,3 BENZODIXOL 5 YLMETHYLIDENE) 2 THIOXO 1,3 THIAZOLIDIN 4 ONE HYDROCHLORIDE; 3 (2 AMINOETHYL) 5 (4 METHOXYBENZYLIDENE) 2 THIOXO 1,3 THIAZOLIDIN 4 ONE HYDROCHLORIDE; 3 (4 AMINOBUTYL) 5 (1,3 BENZODIXOL 5 YLMETHYLIDENE) 2 THIOXO 1,3 THIAZOLIDIN 4 ONE HYDROCHLORIDE; 5 (1,3 BENZODIOXOL 5 YLMETHYLIDENE) 3 [2 [5 (4 METHOXYBENZYLIDENE) 4 OXO 2 THIOXO 1,3 THIAZOLIDIN 3YL]ETHYL] 2 THIOXO 1,3 THIAZOLIDIN 4 ONE; 5 (1,3 BENZODIOXOL 5 YLMETHYLIDENE) 3 [2 [5 BENZYLIDENE 4 OXO 2 THIOXO 1,3 THIAZOLIDIN 3YL]ETHYL] 2 THIOXO 1,3 THIAZOLIDIN 4 ONE; 5 BENZYLIDENE 3 [2 [5 (4 METHOXYBENZYLIDENE) 4 OXO 2 THIOXO 1,3 THIAZOLIDIN 3YL]ETHYL] 2 THIOXO 1,3 THIAZOLIDIN 4 ONE; ANTINEOPLASTIC AGENT; EXOCYCLIC DOUBLE BOND; RHODANINE; ROSCOVITINE; TERT BUTYL (2 AMINOETHYL)CARBAMATE; TERT BUTYL (4 AMINOBUTYL)CARBAMATE; TERT BUTYL [2 [4 (3 AMINOPROPYL)PIPERAZIN 1YL]PROPYL]CARBAMATE; TERT BUTYL [2 [5 (1,3 BENZODIOXOL 5YLMETHYLIDENE) 4 OXO 2 THIOXO 1,3 THIAZOLIDIN 3 YL)BUTYL]CARBAMATE; TERT BUTYL [2 [5 (1,3 BENZODIOXOL 5YLMETHYLIDENE) 4 OXO 2 THIOXO 1,3 THIAZOLIDIN 3 YL)ETHYL]CARBAMATE; TERT BUTYL [2 [5 (4 METHOXYBENZYLIDENE) 4 OXO 2 THIOXO 1,3 THIAZOLIDIN 3 YL]BUTYL]CARBAMATE; TERT BUTYL [2 [5 (4 METHOXYBENZYLIDENE) 4 OXO 2 THIOXO 1,3 THIAZOLIDIN 3 YL]ETHYL]CARBAMATE; TERT BUTYL [[4 [[5 (1,3 BENZODIOXOL 5 YLMETHYLIDENE) 4 OXO 2 THIOXO 1,3 THIAZOLIDIN 3 YL]PROPYL]PIPERAZIN 1 YL]PROPYL]CARBAMATE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DRUG SYNTHESIS; HEATING; IN VITRO STUDY; KNOEVENAGEL CONDENSATION; MELTING POINT; MICROWAVE IRRADIATION; PROSPECTIVE STUDY; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; REACTION OPTIMIZATION; REACTION TIME; THERMODYNAMICS; THIN LAYER CHROMATOGRAPHY; TUMOR CELL LINE;

EID: 84923879339     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-014-1186-7     Document Type: Article

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