Benzylidene 2-aminoimidazolones derivatives: Synthesis and in vitro evaluation of anti-tumor carcinoma activity

Chemical and Pharmaceutical Bulletin

Volumn 61, Issue 10, 2013, Pages 1081-1084

  Ling, Yong ^a   Wang, Zhi Qiang ^a,b   Xiao, You An ^a,c   Zhu, Chenyu ^a   Shen, Liucen ^a   Wang, Xue Min ^a   Hui, Yi ^a   Wang, Xin Yang ^a  

^a NANTONG MEDICAL COLLEGE   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

^c ANHUI UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

2 aminoimidazolone derivative; Anti tumor agent; Cell apoptosis; Inhibitory activity; Synthesis

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BENZYLIDENE 2 AMINOIMIDAZOLONE DERIVATIVE; FLUOROURACIL; IMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER THERAPY; CELL PROLIFERATION; CONTROLLED STUDY; DRUG INHIBITION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IC 50; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZYLIDENE COMPOUNDS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; HEP G2 CELLS; HUMANS; IMIDAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84886670315     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.c13-00340     Document Type: Article

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