Alopecurone B reverses doxorubicin-resistant human osteosarcoma cell line by inhibiting P-glycoprotein and NF-kappa B signaling

Phytomedicine

Volumn 22, Issue 3, 2015, Pages 344-351

  Xia, Yuan Zheng ^a   Ni, Kai ^a   Guo, Chao ^a   Zhang, Chao ^a   Geng, Ya Di ^a   Wang, Zhen Dong ^a   Yang, Lei ^a   Kong, Ling Yi ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Alopecurone B; Doxorubicin; Flavonoid; Multidrug resistance; Nuclear factor kappa B; P glycoprotein

Indexed keywords

ALOPECURONE B; DOXORUBICIN; FLAVONOID; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; PYRROLIDINE DITHIOCARBAMATE; UNCLASSIFIED DRUG; ABCB1 PROTEIN, HUMAN; ANTINEOPLASTIC AGENT; STILBENE DERIVATIVE;

APOPTOSIS; ARTICLE; CANCER RESISTANCE; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; CELL VIABILITY ASSAY; CONTROLLED STUDY; DRUG MECHANISM; DRUG SENSITIVITY; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; FLUORESCENCE; GENE EXPRESSION; HUMAN; HUMAN CELL; IC50; LUCIFERASE ASSAY; MTT ASSAY; OSTEOSARCOMA; OSTEOSARCOMA CELL LINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; DRUG EFFECTS; DRUG RESISTANCE; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

SOPHORA ALOPECUROIDES;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; FLAVONOIDS; HUMANS; NF-KAPPA B; OSTEOSARCOMA; P-GLYCOPROTEINS; SIGNAL TRANSDUCTION; STILBENES;

EID: 84923865414     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2014.12.011     Document Type: Article

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