Oxidative stress-induced apoptosis and matrix loss of chondrocytes is inhibited by eicosapentaenoic acid

Journal of Orthopaedic Research

Volumn 33, Issue 3, 2015, Pages 359-365

  Sakata, Shuhei ^a   Hayashi, Shinya ^a   Fujishiro, Takaaki ^a   Kawakita, Kohei ^a   Kanzaki, Noriyuki ^a   Hashimoto, Shingo ^a   Iwasa, Kenjiro ^a   Chinzei, Nobuaki ^a   Kihara, Shinsuke ^a   Haneda, Masahiko ^a   Ueha, Takeshi ^a   Nishiyama, Takayuki ^a   Kuroda, Ryosuke ^a   Kurosaka, Masahiro ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Chondrocyte; Eicosapentaenoic acid; Matrix metalloproteinase; Osteoarthritis

Indexed keywords

CASPASE 3; COLLAGENASE 3; CORN OIL; ICOSAPENTAENOIC ACID; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITROPRUSSIDE SODIUM; PROTEIN P53; STROMELYSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARTILAGE CELL; CELL DEGENERATION; CELL LOSS; COMPARATIVE STUDY; CONTROLLED STUDY; DENSITOMETRY; DISEASE COURSE; DNA FRAGMENTATION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NICK END LABELING; NONHUMAN; OSTEOARTHRITIS; OSTEOSCLEROSIS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SYNOVITIS; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION;

ANIMALS; APOPTOSIS; CASPASE 3; CELLS, CULTURED; CHONDROCYTES; EICOSAPENTAENOIC ACID; HUMANS; MATRIX METALLOPROTEINASE 13; MICE; MICE, INBRED C57BL; NITROPRUSSIDE; OSTEOARTHRITIS; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84923812968     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.22767     Document Type: Article

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