PTEN regulates matrix synthesis in adult human chondrocytes under oxidative stress

Journal of Orthopaedic Research

Volumn 32, Issue 2, 2014, Pages 231-237

  Iwasa, Kenjiro ^a   Hayashi, Shinya ^a   Fujishiro, Takaaki ^a   Kanzaki, Noriyuki ^a   Hashimoto, Shingo ^a   Sakata, Shuhei ^a   Chinzei, Nobuaki ^a   Nishiyama, Takayuki ^a   Kuroda, Ryosuke ^a   Kurosaka, Masahiro ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

aggrecan; chondrocytes; oxidative stress; PTEN; type2 collagen

Indexed keywords

AGGRECAN; COLLAGEN TYPE 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEOGLYCAN; SMALL INTERFERING RNA; SOMATOMEDIN C; TERT BUTYL HYDROPEROXIDE;

ARTICLE; CARTILAGE CELL; CONTROLLED STUDY; DOWN REGULATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; KNEE OSTEOARTHRITIS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOGLYCAN SYNTHESIS; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

AGGRECAN; CHONDROCYTES; OXIDATIVE STRESS; PTEN; TYPE2 COLLAGEN;

ADULT; AGGRECANS; CHONDROCYTES; COLLAGEN TYPE II; EXTRACELLULAR MATRIX; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; INSULIN-LIKE GROWTH FACTOR I; OSTEOARTHRITIS; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEOGLYCANS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RNA, MESSENGER;

EID: 84890569851     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.22506     Document Type: Article

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