A solute carrier family 22 member 3 variant rs3088442 g→ a associated with coronary heart disease inhibits lipopolysaccharide-induced inflammatory response

Journal of Biological Chemistry

Volumn 290, Issue 9, 2015, Pages 5328-5340

  Li, Lu ^a   He, Meian ^a   Zhou, Li ^a   Miao, Xiaoping ^a   Wu, Fangqing ^a   Huang, Suli ^a,b   Dai, Xiayun ^a   Wang, Tian ^a   Wu, Tangchun ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SHENZHEN CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOLOGY; DISEASES; FEEDBACK; GENES;

CORONARY HEART DISEASE; GENOME-WIDE ASSOCIATION STUDIES; INFLAMMATORY RESPONSE; LIPOPOLYSACCHARIDES; MOLECULAR ANALYSIS; NEGATIVE FEEDBACK MECHANISM; NUCLEOTIDE POLYMORPHISMS; PUTATIVE BINDING SITES;

HEART;

ADENOSINE; GUANIDINE; HISTAMINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MESSENGER RNA; MICRORNA; MICRORNA 147; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; ORGANIC CATION TRANSPORTER 3; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; MIRN147 MICRORNA, HUMAN; ORGANIC CATION TRANSPORTER; SOLUTE CARRIER FAMILY 22 (ORGANIC CATION TRANSPORTER), MEMBER 3;

3' UNTRANSLATED REGION; AMINO ACID SUBSTITUTION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOINFORMATICS; BLOOD SAMPLING; CHINESE; COMPUTER MODEL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME INHIBITION; GENE; GENE CONTROL; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INTERACTION; GENE LOCATION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC CORRELATION; GENETIC VARIABILITY; GENOTYPE; HEART PROTECTION; HUMAN; HUMAN CELL; ISCHEMIC HEART DISEASE; LEUKOCYTE ADHERENCE; MAJOR CLINICAL STUDY; NEGATIVE FEEDBACK; NUCLEOTIDE BINDING SITE; PERIPHERAL BLOOD MONONUCLEAR CELL; POINT MUTATION; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; PROTEIN RNA BINDING; RISK REDUCTION; RNA GENE; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SLC22A3 GENE; TRANSCRIPTION REGULATION; UPREGULATION; ASIAN CONTINENTAL ANCESTRY GROUP; CASE CONTROL STUDY; CELL CULTURE; CHEMICALLY INDUCED; CHINA; CORONARY ARTERY DISEASE; ETHNOLOGY; GENE EXPRESSION; GENETIC PREDISPOSITION; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HEPG2 CELL LINE; INFLAMMATION; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK FACTOR; RNA INTERFERENCE; TUMOR CELL LINE; WESTERN BLOTTING;

3' UNTRANSLATED REGIONS; ASIAN CONTINENTAL ANCESTRY GROUP; BLOTTING, WESTERN; CASE-CONTROL STUDIES; CELL LINE, TUMOR; CELLS, CULTURED; CHINA; CORONARY DISEASE; GENE EXPRESSION; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEK293 CELLS; HELA CELLS; HEP G2 CELLS; HISTAMINE; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MICRORNAS; ORGANIC CATION TRANSPORT PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RISK FACTORS; RNA INTERFERENCE;

EID: 84923795811     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.584953     Document Type: Article

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