Functional promoter -1271G>C variant of HSPB1 predicts lung cancer risk and survival

Journal of Clinical Oncology

Volumn 28, Issue 11, 2010, Pages 1928-1935

  Guo, Huan ^a   Bai, Yun ^a   Xu, Ping ^a   Hu, Zhibin ^a   Liu, Li ^a   Wang, Fang ^a   Jin, Guangfu ^a   Wang, Feng ^a   Deng, Qifei ^a   Tu, Yixiao ^a   Feng, Maohui ^a   Lu, Daru ^a   Shen, Hongbing ^a   Wu, Tangchun ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN 27; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; HSPB1 PROTEIN, HUMAN; LUCIFERASE; POLYCYCLIC AROMATIC HYDROCARBON;

ADULT; ADVANCED CANCER; AGED; ALLELE; ARTICLE; CANCER RISK; CANCER SURVIVAL; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DNA DAMAGE; FEMALE; GENE EXPRESSION; GENE REPLICATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN TISSUE; LUNG CANCER; LUNG NON SMALL CELL CANCER; LUNG PARENCHYMA; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; OCCUPATIONAL EXPOSURE; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM; ADENOCARCINOMA; CASE CONTROL STUDY; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; GENETICS; LUNG SMALL CELL CANCER; LUNG TUMOR; METABOLISM; METASTASIS; MIDDLE AGED; MORTALITY; PATHOLOGY; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE; WESTERN BLOTTING;

ADENOCARCINOMA; AGED; BLOTTING, WESTERN; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; FEMALE; GENETIC ASSOCIATION STUDIES; HSP27 HEAT-SHOCK PROTEINS; HUMANS; LUCIFERASES; LUNG NEOPLASMS; MALE; MIDDLE AGED; OCCUPATIONAL EXPOSURE; POLYCYCLIC HYDROCARBONS, AROMATIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; PROMOTER REGIONS, GENETIC; SMALL CELL LUNG CARCINOMA; SURVIVAL RATE;

EID: 77951651432     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2009.24.4954     Document Type: Article

References (46)

1. Yang L, Parkin DM, Li LD, et al: Estimation and projection of the national profile of cancer mortality in China: 1991-2005. Br J Cancer 90:2157-2166, 2004
2. Jemal A, Siegel R, Ward E, et al: Cancer statistics, 2008. CA Cancer J Clin 58:71-96, 2008
3. Bosetti C, Boffetta P, La Vecchia C: Occupational exposures to polycyclic aromatic hydrocarbons, and respiratory and urinary tract cancers: A quantitative review to 2005. Ann Oncol 18:431-446, 2007
4. Shields PG, Harris CC: Cancer risk and low-penetrance susceptibility genes in gene-environment interactions. J Clin Oncol 18:2309-2315, 2000 (Pubitemid 30350224)
5. Herbst RS, Heymach JV, Lippman SM: Lung cancer. N Engl J Med 359:1367-1380, 2008
6. Ciocca DR, Oesterreich S, Chamness GC, et al: Biological and clinical implications of heat shock protein 27,000 (Hsp27): A review. J Natl Cancer Inst 85:1558-1570, 1993 (Pubitemid 23304684)
7. Merendino AM, Paul C, Vignola AM, et al: Heat shock protein-27 protects human bronchial epithelial cells against oxidative stress-mediated apoptosis: Possible implication in asthma. Cell Stress Chaperones 7:269-280, 2002 (Pubitemid 36135075)
8. Bruey JM, Ducasse C, Bonniaud P, et al: Hsp27 negatively regulates cell death by interacting with cytochrome c. Nat Cell Biol 2:645-652, 2000
9. Paul C, Manero F, Gonin S, et al: Hsp27 as a negative regulator of cytochrome C release. Mol Cell Biol 22:816-834, 2002 (Pubitemid 34053061)
10. Chauhan D, Li G, Hideshima T, et al: Hsp27 inhibits release of mitochondrial protein Smac in multiple myeloma cells and confers dexamethasone resistance. Blood 102:3379-3386, 2003 (Pubitemid 37314781)
11. Charette SJ, Lavoie JN, Lambert H, et al: Inhibition of Daxx-mediated apoptosis by heat shock protein 27. Mol Cell Biol 20:7602-7612, 2000
12. Mendez F, Sandigursky M, Franklin WA, et al: Heat-shock proteins associated with base excision repair enzymes in HeLa cells. Radiat Res 153:186-195, 2000 (Pubitemid 30073854)
13. Nadin SB, Vargas-Roig LM, Drago G, et al: Hsp27, Hsp70 and mismatch repair proteins hMLH1 and hMSH2 expression in peripheral blood lymphocytes from healthy subjects and cancer patients. Cancer Lett 252:131-146, 2007
14. Kim EH, Lee HJ, Lee DH, et al: Inhibition of heat shock protein 27-mediated resistance to DNA damaging agents by a novel PKC delta-V5 heptapeptide. Cancer Res 67:6333-6341, 2007
15. Mosser DD, Morimoto RI: Molecular chaperones and the stress of oncogenesis. Oncogene 23:2907-2918, 2004 (Pubitemid 38638852)
16. Ciocca DR, Calderwood SK: Heat shock proteins in cancer: Diagnostic, prognostic, predictive, and treatment implications. Cell Stress Chaperones 10:86-103, 2005 (Pubitemid 40942470)
17. Calderwood SK, Khaleque MA, Sawyer DB, et al: Heat shock proteins in cancer: Chaperones of tumorigenesis. Trends Biochem Sci 31:164-172, 2006 (Pubitemid 43361923)
18. Garrido C, Fromentin A, Bonnotte B, et al: Heat shock protein 27 enhances the tumorigenicity of immunogenic rat colon carcinoma cell clones. Cancer Res 58:5495-5499, 1998 (Pubitemid 28551136)
19. Kamada M, So A, Muramaki M, et al: Hsp27 knockdown using nucleotide-based therapies inhibit tumor growth and enhance chemotherapy in human bladder cancer cells. Mol Cancer Ther 6:299-308, 2007 (Pubitemid 46206694)
20. Lee YJ, Lee DH, Cho CK, et al: HSP25 inhibits radiation-induced apoptosis through reduction of PKCdelta-mediated ROS production. Oncogene 24:3715-3725, 2005
21. Zhang Y, Shen X: Heat shock protein 27 protects L929 cells from cisplatin-induced apoptosis by enhancing Akt activation and abating suppression of thioredoxin reductase activity. Clin Cancer Res 13:2855-2864, 2007 (Pubitemid 46849558)
22. O'Callaghan-Sunol C, Gabai VL, Sherman MY: Hsp27 modulates p53 signaling and suppresses cellular senescence. Cancer Res 67:11779-11788, 2007
23. He M, Guo H, Yang X, et al: Functional SNPs in HSPA1A gene predict risk of coronary heart disease. PLoS ONE 4:e4851, 2009
24. Yang M, Guo H, Wu C, et al: Functional FEN1 polymorphisms are associated with DNA damage levels and lung cancer risk. Hum Mutat 30:1320-1328, 2009
25. Bai Y, Xu L, Yang X, et al: Sequence variations in DNA repair gene XPC is associated with lung cancer risk in a Chinese population: A case-control study. BMC Cancer 7:81, 2007
26. Hu Z, Chen J, Tian T, et al: Genetic variants of miRNA sequences and non-small cell lung cancer survival. J Clin Invest 118:2600-2608, 2008 (Pubitemid 351949787)
27. Sobin LH, Wittekind CH: TNM classification of malignant tumors (ed 6). New York, NY, Wiley-Liss, 2002
28. Wang H, Chen W, Zheng H, et al: Association between plasma BPDE-Alb adduct concentrations and DNA damage of peripheral blood lymphocytes among coke oven workers. Occup Environ Med 64:753-758, 2007 (Pubitemid 350044089)
29. Singh NP, McCoy MT, Tice RR, et al: A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 175:184-191, 1988
30. Tregouet DA, Garelle V: A new JAVA interface implementation of THESIAS: Testing haplotype effects in association studies. Bioinformatics 23:1038-1039, 2007 (Pubitemid 47050595)
31. Stephens M, Donnelly P: A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet 73:1162-1169, 2003 (Pubitemid 37414228)
32. Barrett JC, Fry B, Maller J, et al: Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-265, 2005 (Pubitemid 40202029)
33. Concannon CG, Gorman AM, Samali A: On the role of Hsp27 in regulating apoptosis. Apoptosis 8:61-70, 2003 (Pubitemid 36133139)
34. Pivovarova AV, Chebotareva NA, Chernik IS, et al: Small heat shock protein Hsp27 prevents heat-induced aggregation of F-actin by forming soluble complexes with denatured actin. FEBS J 274:5937-5948, 2007 (Pubitemid 350045805)
35. Yao H, Zhang Z, Xiao Z, et al: Identification of metastasis associated proteins in human lung squamous carcinoma using two-dimensional difference gel electrophoresis and laser capture microdissection. Lung Cancer 65:41-48, 2009
36. Mori-Iwamoto S, Kuramitsu Y, Ryozawa S, et al: Proteomics finding heat shock protein 27 as a biomarker for resistance of pancreatic cancer cells to gemcitabine. Int J Oncol 31:1345-1350, 2007
37. Ciocca DR, Rozados VR, Cuello Carrión FD, et al: Hsp25 and Hsp70 in rodent tumors treated with doxorubicin and lovastatin. Cell Stress Chaperones 8:26-36, 2003 (Pubitemid 36444088)
38. Dierick I, Irobi J, Janssens S, et al: Genetic variant in the HSPB1 promoter region impairs the HSP27 stress response. Hum Mutat 28:830, 2007
39. Genomatix: MatInspector: Search transcription factor binding sites. http://www.genomatix.de/products/MatInspector/
40. Hanai J, Dhanabal M, Karumanchi SA, et al: Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1. J Biol Chem 277:16464-16469, 2002 (Pubitemid 34967659)
41. Huang YT, Heist RS, Chirieac LR, et al: Genome-wide analysis of survival in early-stage non-small-cell lung cancer. J Clin Oncol 27:2660-2667, 2009
42. Tomida S, Takeuchi T, Shimada Y, et al: Relapse-related molecular signature in lung adenocarcinomas identifies patients with dismal prognosis. J Clin Oncol 27:2793-2799, 2009
43. Shedden K, Taylor JM, Enkemann SA, et al: Gene expression-based survival prediction in lung adenocarcinoma: A multi-site, blinded validation study. Nat Med 14:822-827, 2008
44. Zheng Z, Chen T, Li X, et al: DNA synthesis and repair genes RRM1 and ERCC1 in lung cancer. N Engl J Med 356:800-808, 2007 (Pubitemid 46294612)
45. Calderwood SK, Ciocca DR: Heat shock proteins: Stress proteins with Janus-like properties in cancer. Int J Hyperthermia 24:31-39, 2008 (Pubitemid 351167617)
46. Arrigo AP, Simon S, Gibert B, et al: Hsp27 (HspB1) and alphaB-crystallin (HspB5) as therapeutic targets. FEBS Lett 581:3665-3674, 2007 (Pubitemid 47086314)