CD14 promoter polymorphism is associated with acute myocardial infarction resulting from insignificant coronary artery stenosis

Heart

Volumn 89, Issue 8, 2003, Pages 931-932

  Kondo, Takahisa ^a   Ohno, M ^b   Shimokata, K ^a   Iino, S ^a   Inden, Y ^a   Murohara, T ^a   Hirai, M ^c  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b JAPANESE RED CROSS NAGOYA FIRST HOSPITAL   (Japan)

^c NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN;

ACUTE HEART INFARCTION; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY OBSTRUCTION; DISEASE ASSOCIATION; DNA POLYMORPHISM; GENOTYPE; GRAM NEGATIVE INFECTION; HUMAN; MACROPHAGE ACTIVATION; MAJOR CLINICAL STUDY; MONOCYTE; PRIORITY JOURNAL; PROMOTER REGION;

EID: 0041666485     PISSN: 13556037     EISSN: None     Source Type: Journal    
DOI: 10.1136/heart.89.8.931     Document Type: Article

References (5)

1. Ridker PM, Cushman M, Stompfer MJ, et al. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 1997;336:973-9.
2. Hubacek JA, Rothe G, Pit'ha J, et al. C(-260)→T polymorphism in the promoter of the CD14 monocyte receptor gene as a risk factor for myocardial infarction. Circulation 1999;99:3218-20.
3. Unkelbach K, Gardemann A, Kostrzewa M, et al. A new promoter polymorphism in the gene of lipopolysaccharide receptor CD14 is associated with expired myocardial infarction in patients with low atherosclerotic risk profile. Arterioscler Thromb Vasc Biol 1999;19:932-8.
4. Shimada K, Watanabe Y, Mokuno H, et al. Common polymorphism in the promoter of the CD14 monocyte receptor gene is associated with acute myocardial infarction in Japanese men. Am J Cardiol 2000;86:682-4, A8.
5. Zee RY, Lindpaintner K, Struk B, et al. A prospective evaluation of the CD14 C(-260)T gene polymorphism and the risk of myocardial infarction. Atherosclerosis 2001;154:699-702.