Insulin requires normal expression and signaling of insulin receptor A to reverse gestational diabetes-reduced adenosine transport in human umbilical vein endothelium

FASEB Journal

Volumn 29, Issue 1, 2015, Pages 37-49

  Westermeier, Francisco ^a,b   Salomón, Carlos ^a,c   Farías, Marcelo ^a   Arroyo, Pablo ^a   Fuenzalida, Bárbara ^a   Sáez, Tamara ^a   Salsoso, Rocío ^a   Sanhueza, Carlos ^a   Guzmán Gutiérrez, Enrique ^a,d   Pardo, Fabián ^a   Leiva, Andrea ^a   Sobrevia, Luis ^a,c,e  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d UNIVERSIDAD SAN SEBASTIÁN   (Chile)

^e UNIVERSITY OF SEVILLE   (Spain)

Author keywords

Endothelial dysfunction; Human placenta; Nucleoside membrane transport

Indexed keywords

ADENOSINE; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR A; INSULIN RECEPTOR B; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; UNCLASSIFIED DRUG; INSR PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; SLC29A1 PROTEIN, HUMAN;

ADULT; ARTICLE; CELL LEVEL; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; GENE SILENCING; GENETIC TRANSFECTION; HIGH BIRTH WEIGHT; HUMAN; HUMAN CELL; INFANT; LARGE FOR GESTATIONAL AGE; NUCLEOSIDE TRANSPORT; PLACENTAL TRANSFER; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SUBUNIT; SIGNAL TRANSDUCTION; UMBILICAL CORD BLOOD; ACTIVE TRANSPORT; ADOLESCENT; ANTAGONISTS AND INHIBITORS; CASE CONTROL STUDY; GENE EXPRESSION; GENETICS; KINETICS; MALE; METABOLISM; NEWBORN; PREGNANCY; PROMOTER REGION; UMBILICAL VEIN; UMBILICAL VEIN ENDOTHELIAL CELL; YOUNG ADULT;

ADENOSINE; ADOLESCENT; ADULT; ANTIGENS, CD; BIOLOGICAL TRANSPORT, ACTIVE; CASE-CONTROL STUDIES; DIABETES, GESTATIONAL; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1; FEMALE; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFANT, NEWBORN; INSULIN; KINETICS; MALE; MAP KINASE SIGNALING SYSTEM; PREGNANCY; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, INSULIN; RNA, MESSENGER; SIGNAL TRANSDUCTION; UMBILICAL VEINS; YOUNG ADULT;

EID: 84923544570     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-254219     Document Type: Article

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