메뉴 건너뛰기




Volumn 96, Issue 1, 2015, Pages 1-10

Syndecans: From peripheral coreceptors to mainstream regulators of cell behaviour

Author keywords

Cytoskeleton; Glycosaminoglycan; Heparan sulphate; Proteoglycan

Indexed keywords

SYNDECAN; CELL SURFACE RECEPTOR; LIGAND;

EID: 84923437834     PISSN: 09599673     EISSN: 13652613     Source Type: Journal    
DOI: 10.1111/iep.12112     Document Type: Review
Times cited : (85)

References (83)
  • 2
    • 84863206297 scopus 로고    scopus 로고
    • Syndecan-syntenin-ALIX regulates the biogenesis of exosomes
    • Baietti M.F., Zhang Z., Mortier E. et al. (2012) Syndecan-syntenin-ALIX regulates the biogenesis of exosomes. Nat. Cell Biol. 14, 677-685.
    • (2012) Nat. Cell Biol. , vol.14 , pp. 677-685
    • Baietti, M.F.1    Zhang, Z.2    Mortier, E.3
  • 3
    • 45349086241 scopus 로고    scopus 로고
    • p190RhoGAP is the convergence point of adhesion signals from alpha 5 beta 1 integrin and syndecan-4
    • Bass M.D., Morgan M.R., Roach K.A., Settleman J., Goryachev A.B. & Humphries M.J. (2008) p190RhoGAP is the convergence point of adhesion signals from alpha 5 beta 1 integrin and syndecan-4. J. Cell Biol. 181, 1013-1026.
    • (2008) J. Cell Biol. , vol.181 , pp. 1013-1026
    • Bass, M.D.1    Morgan, M.R.2    Roach, K.A.3    Settleman, J.4    Goryachev, A.B.5    Humphries, M.J.6
  • 5
    • 84874403806 scopus 로고    scopus 로고
    • Syndecan 4 supports bone fracture repair, but not fetal skeletal development, in mice
    • Bertrand J., Stange R., Hidding H. et al. (2013) Syndecan 4 supports bone fracture repair, but not fetal skeletal development, in mice. Arthritis Rheum. 65, 743-752.
    • (2013) Arthritis Rheum. , vol.65 , pp. 743-752
    • Bertrand, J.1    Stange, R.2    Hidding, H.3
  • 6
    • 0032526145 scopus 로고    scopus 로고
    • Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase
    • Bullock S.L., Fletcher J.M., Beddington R.S. & Wilson V.A. (1998) Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase. Genes Dev. 12, 1894-1906.
    • (1998) Genes Dev. , vol.12 , pp. 1894-1906
    • Bullock, S.L.1    Fletcher, J.M.2    Beddington, R.S.3    Wilson, V.A.4
  • 7
    • 66449083531 scopus 로고    scopus 로고
    • Mutations in heparan sulfate-proteoglycan glypican 6 (GPC6) impair endochondral ossification and cause recessive omodysplasia
    • Campos-Xavier A.B., Martinet D., Bateman J. et al. (2009) Mutations in heparan sulfate-proteoglycan glypican 6 (GPC6) impair endochondral ossification and cause recessive omodysplasia. Am. J. Hum. Genet. 84, 760-770.
    • (2009) Am. J. Hum. Genet. , vol.84 , pp. 760-770
    • Campos-Xavier, A.B.1    Martinet, D.2    Bateman, J.3
  • 8
    • 33646751461 scopus 로고    scopus 로고
    • Comparative genomics of the syndecans defines an ancestral genomic context associated with matrilins in vertebrates
    • Chakravarti R. & Adams J.C. (2006) Comparative genomics of the syndecans defines an ancestral genomic context associated with matrilins in vertebrates. BMC Genom. 7, 83.
    • (2006) BMC Genom. , vol.7 , pp. 83
    • Chakravarti, R.1    Adams, J.C.2
  • 9
    • 60349109301 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 modulates melanoma adhesion and migration through a syndecan-4-dependent mechanism
    • Chalkiadaki G., Nikitovic D., Berdiaki A. et al. (2009) Fibroblast growth factor-2 modulates melanoma adhesion and migration through a syndecan-4-dependent mechanism. Int. J. Biochem. Cell Biol. 41, 1323-1331.
    • (2009) Int. J. Biochem. Cell Biol. , vol.41 , pp. 1323-1331
    • Chalkiadaki, G.1    Nikitovic, D.2    Berdiaki, A.3
  • 10
    • 67749111948 scopus 로고    scopus 로고
    • Reception of Slit requires only the chondroitin-sulphate-modified extracellular domain of Syndecan at the target cell surface
    • Chanana B., Steigemann P., Jäckle H. & Vorbrüggen G. (2009) Reception of Slit requires only the chondroitin-sulphate-modified extracellular domain of Syndecan at the target cell surface. Proc. Natl Acad. Sci. USA 106, 11984-11988.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 11984-11988
    • Chanana, B.1    Steigemann, P.2    Jäckle, H.3    Vorbrüggen, G.4
  • 11
    • 26244438018 scopus 로고    scopus 로고
    • Protein kinase Cdelta-dependent phosphorylation of syndecan-4 regulates cell migration
    • Chaudhuri P., Colles S.M., Fox P.L. & Graham L.M. (2005) Protein kinase Cdelta-dependent phosphorylation of syndecan-4 regulates cell migration. Circ. Res. 97, 674-681.
    • (2005) Circ. Res. , vol.97 , pp. 674-681
    • Chaudhuri, P.1    Colles, S.M.2    Fox, P.L.3    Graham, L.M.4
  • 12
    • 84877901149 scopus 로고    scopus 로고
    • Molecular mediators for raft-dependent endocytosis of syndecan-1, a highly conserved, multifunctional receptor
    • Chen K. & Williams K.J. (2013) Molecular mediators for raft-dependent endocytosis of syndecan-1, a highly conserved, multifunctional receptor. J. Biol. Chem. 288, 13988-13999.
    • (2013) J. Biol. Chem. , vol.288 , pp. 13988-13999
    • Chen, K.1    Williams, K.J.2
  • 13
    • 78049404922 scopus 로고    scopus 로고
    • Transmembrane signaling proteoglycans
    • Couchman J.R. (2010) Transmembrane signaling proteoglycans. Annu. Rev. Cell Dev. Biol. 26, 89-114.
    • (2010) Annu. Rev. Cell Dev. Biol. , vol.26 , pp. 89-114
    • Couchman, J.R.1
  • 14
    • 0022832142 scopus 로고
    • Heparan sulphate proteoglycan as mediator of some adhesive responses and cytoskeletal reorganization of cells on fibronectin matrices: independent versus cooperative functions
    • Culp L.A., Laterra J., Lark M.W., Beyth R.J. & Tobey S.L. (1986) Heparan sulphate proteoglycan as mediator of some adhesive responses and cytoskeletal reorganization of cells on fibronectin matrices: independent versus cooperative functions. Ciba Found. Symp. 124, 158-183.
    • (1986) Ciba Found. Symp. , vol.124 , pp. 158-183
    • Culp, L.A.1    Laterra, J.2    Lark, M.W.3    Beyth, R.J.4    Tobey, S.L.5
  • 15
    • 4444347398 scopus 로고    scopus 로고
    • Chondroitin sulfate chains on syndecan-1 and syndecan-4 from normal murine mammary gland epithelial cells are structurally and functionally distinct and cooperate with heparan sulfate chains to bind growth factors. A novel function to control binding of midkine, pleiotrophin, and basic fibroblast growth factor
    • Deepa S.S., Yamada S., Zako M., Goldberger O. & Sugahara K. (2004) Chondroitin sulfate chains on syndecan-1 and syndecan-4 from normal murine mammary gland epithelial cells are structurally and functionally distinct and cooperate with heparan sulfate chains to bind growth factors. A novel function to control binding of midkine, pleiotrophin, and basic fibroblast growth factor. J. Biol. Chem. 279, 37368-37376.
    • (2004) J. Biol. Chem. , vol.279 , pp. 37368-37376
    • Deepa, S.S.1    Yamada, S.2    Zako, M.3    Goldberger, O.4    Sugahara, K.5
  • 16
    • 0037023787 scopus 로고    scopus 로고
    • Syndesmos, a syndecan-4 cytoplasmic domain interactor, binds to the focal adhesion adaptor proteins paxillin and Hic-5
    • Denhez F., Wilcox-Adelman S.A., Baciu P.C. et al. (2002) Syndesmos, a syndecan-4 cytoplasmic domain interactor, binds to the focal adhesion adaptor proteins paxillin and Hic-5. J. Biol. Chem. 277, 12270-12274.
    • (2002) J. Biol. Chem. , vol.277 , pp. 12270-12274
    • Denhez, F.1    Wilcox-Adelman, S.A.2    Baciu, P.C.3
  • 17
    • 33746918654 scopus 로고    scopus 로고
    • PKCalpha-dependent activation of RhoA by syndecan-4 during focal adhesion formation
    • Dovas A., Yoneda A. & Couchman J.R. (2006) PKCalpha-dependent activation of RhoA by syndecan-4 during focal adhesion formation. J. Cell Sci. 119, 2837-2846.
    • (2006) J. Cell Sci. , vol.119 , pp. 2837-2846
    • Dovas, A.1    Yoneda, A.2    Couchman, J.R.3
  • 18
    • 77954889407 scopus 로고    scopus 로고
    • Serine 34 phosphorylation of rho guanine dissociation inhibitor (RhoGDIalpha) links signaling from conventional protein kinase C to RhoGTPase in cell adhesion
    • Dovas A., Choi Y., Yoneda A. et al. (2010) Serine 34 phosphorylation of rho guanine dissociation inhibitor (RhoGDIalpha) links signaling from conventional protein kinase C to RhoGTPase in cell adhesion. J. Biol. Chem. 285, 23296-23308.
    • (2010) J. Biol. Chem. , vol.285 , pp. 23296-23308
    • Dovas, A.1    Choi, Y.2    Yoneda, A.3
  • 19
    • 0035145150 scopus 로고    scopus 로고
    • Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4
    • Echtermeyer F., Streit M., Wilcox-Adelman S. et al. (2001) Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4. J. Clin. Invest. 107, R9-R14.
    • (2001) J. Clin. Invest. , vol.107 , pp. R9-R14
    • Echtermeyer, F.1    Streit, M.2    Wilcox-Adelman, S.3
  • 20
    • 69949118870 scopus 로고    scopus 로고
    • Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis
    • Echtermeyer F., Bertrand J., Dreier R. et al. (2009) Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis. Nat. Med. 15, 1072-1076.
    • (2009) Nat. Med. , vol.15 , pp. 1072-1076
    • Echtermeyer, F.1    Bertrand, J.2    Dreier, R.3
  • 21
    • 4744368711 scopus 로고    scopus 로고
    • Inhibition by the soluble syndecan-1 ectodomains delays wound repair in mice overexpressing syndecan-1
    • Elenius V., Götte M., Reizes O., Elenius K. & Bernfield M. (2004) Inhibition by the soluble syndecan-1 ectodomains delays wound repair in mice overexpressing syndecan-1. J. Biol. Chem. 279, 41928-41935.
    • (2004) J. Biol. Chem. , vol.279 , pp. 41928-41935
    • Elenius, V.1    Götte, M.2    Reizes, O.3    Elenius, K.4    Bernfield, M.5
  • 22
    • 33749441307 scopus 로고    scopus 로고
    • The role of syndecans in disease and wound healing
    • Fears C.Y. & Woods A. (2006) The role of syndecans in disease and wound healing. Matrix Biol. 25, 443-456.
    • (2006) Matrix Biol. , vol.25 , pp. 443-456
    • Fears, C.Y.1    Woods, A.2
  • 23
    • 84877686831 scopus 로고    scopus 로고
    • Glypican-3: a marker and a therapeutic target in hepatocellular carcinoma
    • Filmus J. & Capurro M. (2013) Glypican-3: a marker and a therapeutic target in hepatocellular carcinoma. FEBS J. 280, 2471-2476.
    • (2013) FEBS J. , vol.280 , pp. 2471-2476
    • Filmus, J.1    Capurro, M.2
  • 24
    • 84901462346 scopus 로고    scopus 로고
    • The role of glypicans in hedgehog signaling
    • Filmus J. & Capurro M. (2014) The role of glypicans in hedgehog signaling. Matrix Biol. 35, 248-252.
    • (2014) Matrix Biol. , vol.35 , pp. 248-252
    • Filmus, J.1    Capurro, M.2
  • 26
    • 84897865127 scopus 로고    scopus 로고
    • Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2
    • Ghossoub R., Lembo F., Rubio A. et al. (2014) Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2. Nat. Commun. 5, 3477.
    • (2014) Nat. Commun. , vol.5 , pp. 3477
    • Ghossoub, R.1    Lembo, F.2    Rubio, A.3
  • 28
    • 0037387945 scopus 로고    scopus 로고
    • Syndecans in inflammation
    • Götte M. (2003) Syndecans in inflammation. FASEB J. 17, 575-591.
    • (2003) FASEB J. , vol.17 , pp. 575-591
    • Götte, M.1
  • 29
    • 84884185123 scopus 로고    scopus 로고
    • A network of HSPG core proteins and HS modifying enzymes regulates netrin-dependent guidance of D-type motor neurons in Caenorhabditis elegans
    • Gysi S., Rhiner C., Flibotte S., Moerman D.G. & Hengartner M.O. (2013) A network of HSPG core proteins and HS modifying enzymes regulates netrin-dependent guidance of D-type motor neurons in Caenorhabditis elegans. PLoS ONE 8, e74908.
    • (2013) PLoS ONE , vol.8 , pp. e74908
    • Gysi, S.1    Rhiner, C.2    Flibotte, S.3    Moerman, D.G.4    Hengartner, M.O.5
  • 30
    • 84871836123 scopus 로고    scopus 로고
    • Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress
    • Herum K.M., Lunde I.G., Skribic B. et al. (2013) Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress. J. Mol. Cell. Cardiol. 54, 73-81.
    • (2013) J. Mol. Cell. Cardiol. , vol.54 , pp. 73-81
    • Herum, K.M.1    Lunde, I.G.2    Skribic, B.3
  • 31
    • 33747199616 scopus 로고    scopus 로고
    • N-syndecan deficiency impairs neural migration in brain
    • Hienola A., Tumova S., Kulesskiy E. & Rauvala H. (2006) N-syndecan deficiency impairs neural migration in brain. J. Cell Biol. 174, 569-580.
    • (2006) J. Cell Biol. , vol.174 , pp. 569-580
    • Hienola, A.1    Tumova, S.2    Kulesskiy, E.3    Rauvala, H.4
  • 32
    • 7944230540 scopus 로고    scopus 로고
    • The emergence of integrins: a personal and historical perspective
    • Hynes R.O. (2004) The emergence of integrins: a personal and historical perspective. Matrix Biol. 23, 333-340.
    • (2004) Matrix Biol. , vol.23 , pp. 333-340
    • Hynes, R.O.1
  • 33
    • 79957605232 scopus 로고    scopus 로고
    • Proteoglycans in cancer biology, tumour microenvironment and angiogenesis
    • Iozzo R.V. & Sanderson R.D. (2011) Proteoglycans in cancer biology, tumour microenvironment and angiogenesis. J. Cell Mol. Med. 15, 1013-1031.
    • (2011) J. Cell Mol. Med. , vol.15 , pp. 1013-1031
    • Iozzo, R.V.1    Sanderson, R.D.2
  • 34
    • 0034050724 scopus 로고    scopus 로고
    • Syndecan-4 deficiency impairs focal adhesion formation only under restricted conditions
    • Ishiguro K., Kadomatsu K., Kojima T. et al. (2000) Syndecan-4 deficiency impairs focal adhesion formation only under restricted conditions. J. Biol. Chem. 275, 5249-5252.
    • (2000) J. Biol. Chem. , vol.275 , pp. 5249-5252
    • Ishiguro, K.1    Kadomatsu, K.2    Kojima, T.3
  • 35
    • 77649187760 scopus 로고    scopus 로고
    • Sdc1 negatively modulates carcinoma cell motility and invasion
    • Ishikawa T. & Kramer R.H. (2010) Sdc1 negatively modulates carcinoma cell motility and invasion. Exp. Cell Res. 316, 951-965.
    • (2010) Exp. Cell Res. , vol.316 , pp. 951-965
    • Ishikawa, T.1    Kramer, R.H.2
  • 36
    • 1842587626 scopus 로고    scopus 로고
    • Axonal heparan sulfate proteoglycans regulate the distribution and efficiency of the repellent slit during midline axon guidance
    • Johnson K.G., Ghose A., Epstein E., Lincecum J., O'Connor M.B. & Van Vactor D. (2004) Axonal heparan sulfate proteoglycans regulate the distribution and efficiency of the repellent slit during midline axon guidance. Curr. Biol. 14, 499-504.
    • (2004) Curr. Biol. , vol.14 , pp. 499-504
    • Johnson, K.G.1    Ghose, A.2    Epstein, E.3    Lincecum, J.4    O'Connor, M.B.5    Van Vactor, D.6
  • 37
    • 0029005076 scopus 로고
    • Loss of cell surface syndecan-1 causes epithelia to transform into anchorage-independent mesenchyme-like cells
    • Kato M., Saunders S., Nguyen H. & Bernfield M. (1995) Loss of cell surface syndecan-1 causes epithelia to transform into anchorage-independent mesenchyme-like cells. Mol. Biol. Cell 6, 559-576.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 559-576
    • Kato, M.1    Saunders, S.2    Nguyen, H.3    Bernfield, M.4
  • 38
    • 84904083083 scopus 로고    scopus 로고
    • Syndecan-3 is selectively pro-inflammatory in the joint and contributes to antigen-induced arthritis in mice
    • Kehoe O., Kalia N., King S. et al. (2014) Syndecan-3 is selectively pro-inflammatory in the joint and contributes to antigen-induced arthritis in mice. Arthritis. Res. Ther. 16, R148.
    • (2014) Arthritis. Res. Ther. , vol.16 , pp. R148
    • Kehoe, O.1    Kalia, N.2    King, S.3
  • 39
    • 70350038004 scopus 로고    scopus 로고
    • Syndecan-1 is required for robust growth, vascularization and metastasis of myeloma tumors in vivo
    • Khotskaya Y.B., Dai Y., Ritchie J.P. et al. (2009) Syndecan-1 is required for robust growth, vascularization and metastasis of myeloma tumors in vivo. J. Biol. Chem. 284, 26085-26095.
    • (2009) J. Biol. Chem. , vol.284 , pp. 26085-26095
    • Khotskaya, Y.B.1    Dai, Y.2    Ritchie, J.P.3
  • 40
    • 0032562591 scopus 로고    scopus 로고
    • Cortactin-Src kinase signaling pathway is involved in N-syndecan-dependent neurite outgrowth
    • Kinnunen T., Kaksonen M., Saarinen J., Kalkkinen N., Peng H.B. & Rauvala H. (1998) Cortactin-Src kinase signaling pathway is involved in N-syndecan-dependent neurite outgrowth. J. Biol. Chem. 273, 10702-10708.
    • (1998) J. Biol. Chem. , vol.273 , pp. 10702-10708
    • Kinnunen, T.1    Kaksonen, M.2    Saarinen, J.3    Kalkkinen, N.4    Peng, H.B.5    Rauvala, H.6
  • 41
    • 29144435969 scopus 로고    scopus 로고
    • Structural basis of syndecan-4 phosphorylation as a molecular switch to regulate signaling
    • Koo B.K., Jung Y.S., Shin J. et al. (2006) Structural basis of syndecan-4 phosphorylation as a molecular switch to regulate signaling. J. Mol. Biol. 355, 651-663.
    • (2006) J. Mol. Biol. , vol.355 , pp. 651-663
    • Koo, B.K.1    Jung, Y.S.2    Shin, J.3
  • 42
    • 84903438935 scopus 로고    scopus 로고
    • Nuclear translocation of heparan sulfate proteoglycans and their functional significance
    • Kovalszky I., Hjerpe A. & Dobra K. (2014) Nuclear translocation of heparan sulfate proteoglycans and their functional significance. Biochim. Biophys. Acta 1840, 2491-2497.
    • (2014) Biochim. Biophys. Acta , vol.1840 , pp. 2491-2497
    • Kovalszky, I.1    Hjerpe, A.2    Dobra, K.3
  • 44
    • 84903520797 scopus 로고    scopus 로고
    • Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases
    • Lim H.C. & Couchman J.R. (2014) Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases. Biochim. Biophys. Acta 1840, 2482-2490.
    • (2014) Biochim. Biophys. Acta , vol.1840 , pp. 2482-2490
    • Lim, H.C.1    Couchman, J.R.2
  • 45
    • 0034663225 scopus 로고    scopus 로고
    • Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice
    • Lin X., Wei G., Shi Z. et al. (2000) Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice. Dev. Biol. 224, 299-311.
    • (2000) Dev. Biol. , vol.224 , pp. 299-311
    • Lin, X.1    Wei, G.2    Shi, Z.3
  • 46
    • 77956646126 scopus 로고    scopus 로고
    • Proteoglycans in health and disease: the multiple roles of syndecan shedding
    • Manon-Jensen T., Itoh Y. & Couchman J.R. (2010) Proteoglycans in health and disease: the multiple roles of syndecan shedding. FEBS J. 277, 3876-3889.
    • (2010) FEBS J. , vol.277 , pp. 3876-3889
    • Manon-Jensen, T.1    Itoh, Y.2    Couchman, J.R.3
  • 47
    • 84877721994 scopus 로고    scopus 로고
    • Mapping of matrix metalloproteinase cleavage sites on syndecan-1 and syndecan-4 ectodomains
    • Manon-Jensen T., Multhaupt H.A. & Couchman J.R. (2013) Mapping of matrix metalloproteinase cleavage sites on syndecan-1 and syndecan-4 ectodomains. FEBS J. 280, 2320-2331.
    • (2013) FEBS J. , vol.280 , pp. 2320-2331
    • Manon-Jensen, T.1    Multhaupt, H.A.2    Couchman, J.R.3
  • 50
    • 0037090422 scopus 로고    scopus 로고
    • The role of syndecan-2 in regulation of actin-cytoskeletal organization of Lewis lung carcinoma-derived metastatic clones
    • Munesue S., Kusano Y., Oguri K. et al. (2002) The role of syndecan-2 in regulation of actin-cytoskeletal organization of Lewis lung carcinoma-derived metastatic clones. Biochem. J. 363, 201-209.
    • (2002) Biochem. J. , vol.363 , pp. 201-209
    • Munesue, S.1    Kusano, Y.2    Oguri, K.3
  • 51
    • 34948867377 scopus 로고    scopus 로고
    • A novel function of syndecan-2, suppression of matrix metalloproteinase-2 activation, which causes suppression of metastasis
    • Munesue S., Yoshitomi Y., Kusano Y. et al. (2007) A novel function of syndecan-2, suppression of matrix metalloproteinase-2 activation, which causes suppression of metastasis. J. Biol. Chem. 282, 28164-28174.
    • (2007) J. Biol. Chem. , vol.282 , pp. 28164-28174
    • Munesue, S.1    Yoshitomi, Y.2    Kusano, Y.3
  • 52
    • 0037036450 scopus 로고    scopus 로고
    • Protein kinase C (PKC) delta regulates PKCalpha activity in a Syndecan-4-dependent manner
    • Murakami M., Horowitz A., Tang S., Ware J.A. & Simons M. (2002) Protein kinase C (PKC) delta regulates PKCalpha activity in a Syndecan-4-dependent manner. J. Biol. Chem. 277, 20367-20371.
    • (2002) J. Biol. Chem. , vol.277 , pp. 20367-20371
    • Murakami, M.1    Horowitz, A.2    Tang, S.3    Ware, J.A.4    Simons, M.5
  • 53
    • 0033594123 scopus 로고    scopus 로고
    • Rho GTPases control polarity, protrusion, and adhesion during cell movement
    • Nobes C.D. & Hall A. (1999) Rho GTPases control polarity, protrusion, and adhesion during cell movement. J. Cell Biol. 144, 1235-1244.
    • (1999) J. Cell Biol. , vol.144 , pp. 1235-1244
    • Nobes, C.D.1    Hall, A.2
  • 54
    • 0030889054 scopus 로고    scopus 로고
    • Syndecan-4 proteoglycan regulates the distribution and activity of protein kinase C
    • Oh E.S., Woods A. & Couchman J.R. (1997) Syndecan-4 proteoglycan regulates the distribution and activity of protein kinase C. J. Biol. Chem. 272, 8133-8136.
    • (1997) J. Biol. Chem. , vol.272 , pp. 8133-8136
    • Oh, E.S.1    Woods, A.2    Couchman, J.R.3
  • 55
    • 0032562706 scopus 로고    scopus 로고
    • Syndecan-4 proteoglycan cytoplasmic domain and phosphatidylinositol 4,5-bisphosphate coordinately regulate protein kinase C activity
    • Oh E.S., Woods A., Lim S.T., Theibert A.W. & Couchman J.R. (1998) Syndecan-4 proteoglycan cytoplasmic domain and phosphatidylinositol 4, 5-bisphosphate coordinately regulate protein kinase C activity. J. Biol. Chem. 273, 10624-10629.
    • (1998) J. Biol. Chem. , vol.273 , pp. 10624-10629
    • Oh, E.S.1    Woods, A.2    Lim, S.T.3    Theibert, A.W.4    Couchman, J.R.5
  • 56
    • 84866522773 scopus 로고    scopus 로고
    • Alpha-actinin interactions with syndecan-4 are integral to fibroblast-matrix adhesion and regulate cytoskeletal architecture
    • Okina E., Grossi A., Gopal S., Multhaupt H.A. & Couchman J.R. (2012) Alpha-actinin interactions with syndecan-4 are integral to fibroblast-matrix adhesion and regulate cytoskeletal architecture. Int. J. Biochem. Cell Biol. 44, 2161-2174.
    • (2012) Int. J. Biochem. Cell Biol. , vol.44 , pp. 2161-2174
    • Okina, E.1    Grossi, A.2    Gopal, S.3    Multhaupt, H.A.4    Couchman, J.R.5
  • 57
    • 54249090199 scopus 로고    scopus 로고
    • BALB/c and C57BL6 mouse strains vary in their ability to heal corneal epithelial debridement wounds
    • Pal-Ghosh S., Tadvalkar G., Jurjus R.A., Zieske J.D. & Stepp M.A. (2008) BALB/c and C57BL6 mouse strains vary in their ability to heal corneal epithelial debridement wounds. Exp. Eye Res. 87, 478-486.
    • (2008) Exp. Eye Res. , vol.87 , pp. 478-486
    • Pal-Ghosh, S.1    Tadvalkar, G.2    Jurjus, R.A.3    Zieske, J.D.4    Stepp, M.A.5
  • 58
    • 84879605819 scopus 로고    scopus 로고
    • Multi-faceted substrate specificity of heparanase
    • Peterson S.B. & Liu J. (2013) Multi-faceted substrate specificity of heparanase. Matrix Biol. 32, 223-227.
    • (2013) Matrix Biol. , vol.32 , pp. 223-227
    • Peterson, S.B.1    Liu, J.2
  • 59
    • 13344261391 scopus 로고    scopus 로고
    • Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome
    • Pilia G., Highes-Benzie R.M., MacKenzie A. et al. (1996) Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome. Nat. Genet. 12, 241-247.
    • (1996) Nat. Genet. , vol.12 , pp. 241-247
    • Pilia, G.1    Highes-Benzie, R.M.2    MacKenzie, A.3
  • 62
    • 0024556678 scopus 로고
    • Molecular cloning of syndecan, an integral membrane proteoglycan
    • Saunders S., Jalkanen M., O'Farrell S, Bernfield M. (1989) Molecular cloning of syndecan, an integral membrane proteoglycan. J. Cell Biol. 108, 1547-1556.
    • (1989) J. Cell Biol. , vol.108 , pp. 1547-1556
    • Saunders, S.1    Jalkanen, M.2    O'Farrell, S.3    Bernfield, M.4
  • 63
    • 1542677095 scopus 로고    scopus 로고
    • Syndecan 3 intramembrane proteolysis is presenilin/gamma-secretase-dependent and modulates cytosolic signaling
    • Schulz J.G., Annaert W., Vandekerckhove J., Zimmermann P., De Strooper B. & David G. (2003) Syndecan 3 intramembrane proteolysis is presenilin/gamma-secretase-dependent and modulates cytosolic signaling. J. Biol. Chem. 278, 48651-48657.
    • (2003) J. Biol. Chem. , vol.278 , pp. 48651-48657
    • Schulz, J.G.1    Annaert, W.2    Vandekerckhove, J.3    Zimmermann, P.4    De Strooper, B.5    David, G.6
  • 64
    • 80053571864 scopus 로고    scopus 로고
    • Drosophila syndecan regulates tracheal cell migration by stabilizing Robo levels
    • Schulz J.G., Ceulemans H., Caussinus E. et al. (2011) Drosophila syndecan regulates tracheal cell migration by stabilizing Robo levels. EMBO Rep. 12, 1039-1046.
    • (2011) EMBO Rep. , vol.12 , pp. 1039-1046
    • Schulz, J.G.1    Ceulemans, H.2    Caussinus, E.3
  • 65
    • 70249109672 scopus 로고    scopus 로고
    • SDN-1/syndecan regulates growth factor signaling in distal tip cell migrations in C. elegans
    • Schwabiuk M., Coudiere L. & Merz D.C. (2009) SDN-1/syndecan regulates growth factor signaling in distal tip cell migrations in C. elegans. Dev. Biol. 334, 235-342.
    • (2009) Dev. Biol. , vol.334 , pp. 235-342
    • Schwabiuk, M.1    Coudiere, L.2    Merz, D.C.3
  • 66
    • 1242265735 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycan syndecan promotes axonal and myotube guidance by slit/robo signaling
    • Steigemann P., Molitor A., Fellert S., Jäckle H. & Vorbrüggen G. (2004) Heparan sulfate proteoglycan syndecan promotes axonal and myotube guidance by slit/robo signaling. Curr. Biol. 14, 225-230.
    • (2004) Curr. Biol. , vol.14 , pp. 225-230
    • Steigemann, P.1    Molitor, A.2    Fellert, S.3    Jäckle, H.4    Vorbrüggen, G.5
  • 67
    • 12244305625 scopus 로고    scopus 로고
    • Defects in keratinocyte activation during wound healing in the syndecan-1-deficient mouse
    • Stepp M.A., Gibson H.E., Gala P.H. et al. (2002) Defects in keratinocyte activation during wound healing in the syndecan-1-deficient mouse. J. Cell Sci. 115, 4517-4531.
    • (2002) J. Cell Sci. , vol.115 , pp. 4517-4531
    • Stepp, M.A.1    Gibson, H.E.2    Gala, P.H.3
  • 68
    • 84901411217 scopus 로고    scopus 로고
    • Heparan sulfate in the nucleus and its control of cellular functions
    • Stewart M.D. & Sanderson R.D. (2014) Heparan sulfate in the nucleus and its control of cellular functions. Matrix Biol. 35, 56-59.
    • (2014) Matrix Biol. , vol.35 , pp. 56-59
    • Stewart, M.D.1    Sanderson, R.D.2
  • 69
    • 28844450108 scopus 로고    scopus 로고
    • Mice deficient in Ext2 lack heparan sulfate and develop exostoses
    • Stickens D., Zak B.M., Rougier N., Esko J.D. & Werb Z. (2005) Mice deficient in Ext2 lack heparan sulfate and develop exostoses. Development 132, 5055-5068.
    • (2005) Development , vol.132 , pp. 5055-5068
    • Stickens, D.1    Zak, B.M.2    Rougier, N.3    Esko, J.D.4    Werb, Z.5
  • 70
    • 84877711612 scopus 로고    scopus 로고
    • Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart
    • Strand M.E., Herum K.M., Rana Z.A. et al. (2013) Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart. FEBS J. 280, 2228-2247.
    • (2013) FEBS J. , vol.280 , pp. 2228-2247
    • Strand, M.E.1    Herum, K.M.2    Rana, Z.A.3
  • 71
    • 0031876027 scopus 로고    scopus 로고
    • Simultaneous loss of expression of syndecan-1 and E-cadherin in the embryonic palate during epithelial-mesenchymal transformation
    • Sun D., Mcalmon K.R., Davies J.A., Bernfield M. & Hay E.D. (1998) Simultaneous loss of expression of syndecan-1 and E-cadherin in the embryonic palate during epithelial-mesenchymal transformation. Int. J. Dev. Biol. 42, 733-736.
    • (1998) Int. J. Dev. Biol. , vol.42 , pp. 733-736
    • Sun, D.1    Mcalmon, K.R.2    Davies, J.A.3    Bernfield, M.4    Hay, E.D.5
  • 72
    • 0022448122 scopus 로고
    • Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin
    • Tamkun J.W., DeSimone D.W., Fonda D. et al. (1986) Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin. Cell 46, 271-282.
    • (1986) Cell , vol.46 , pp. 271-282
    • Tamkun, J.W.1    DeSimone, D.W.2    Fonda, D.3
  • 73
    • 84864554763 scopus 로고    scopus 로고
    • Syndecan-4 regulates early neutrophil migration and pulmonary inflammation in response to lipopolysaccharide
    • Tanino Y., Chang M.Y., Wang X. et al. (2012) Syndecan-4 regulates early neutrophil migration and pulmonary inflammation in response to lipopolysaccharide. Am. J. Respir. Cell Mol. Biol. 47, 196-202.
    • (2012) Am. J. Respir. Cell Mol. Biol. , vol.47 , pp. 196-202
    • Tanino, Y.1    Chang, M.Y.2    Wang, X.3
  • 74
    • 84855578074 scopus 로고    scopus 로고
    • Molecular functions of syndecan-1 in disease
    • Teng Y.H., Aquino R.S. & Park P.W. (2012) Molecular functions of syndecan-1 in disease. Matrix Biol. 31, 3-16.
    • (2012) Matrix Biol. , vol.31 , pp. 3-16
    • Teng, Y.H.1    Aquino, R.S.2    Park, P.W.3
  • 75
    • 84875994843 scopus 로고    scopus 로고
    • Heparanase regulates secretion, composition, and function of tumor cell-derived exosomes
    • Thompson C.A., Purushothaman A., Ramani V.C., Vlodavsky I. & Sanderson R.D. (2013) Heparanase regulates secretion, composition, and function of tumor cell-derived exosomes. J. Biol. Chem. 288, 10093-10099.
    • (2013) J. Biol. Chem. , vol.288 , pp. 10093-10099
    • Thompson, C.A.1    Purushothaman, A.2    Ramani, V.C.3    Vlodavsky, I.4    Sanderson, R.D.5
  • 76
    • 84898073682 scopus 로고    scopus 로고
    • Loss of syndecan-1 induces a pro-inflammatory phenotype in endothelial cells with a dysregulated response to atheroprotective flow
    • Voyvodic P.L., Min D., Liu R. et al. (2014) Loss of syndecan-1 induces a pro-inflammatory phenotype in endothelial cells with a dysregulated response to atheroprotective flow. J. Biol. Chem. 289, 9547-9559.
    • (2014) J. Biol. Chem. , vol.289 , pp. 9547-9559
    • Voyvodic, P.L.1    Min, D.2    Liu, R.3
  • 77
    • 57649155063 scopus 로고    scopus 로고
    • Structural and cell adhesion properties of zebrafish syndecan-4 are shared with higher vertebrates
    • Whiteford J.R., Ko S., Lee W. & Couchman J.R. (2008) Structural and cell adhesion properties of zebrafish syndecan-4 are shared with higher vertebrates. J. Biol. Chem. 283, 29322-29330.
    • (2008) J. Biol. Chem. , vol.283 , pp. 29322-29330
    • Whiteford, J.R.1    Ko, S.2    Lee, W.3    Couchman, J.R.4
  • 78
    • 0022212764 scopus 로고
    • Heparan sulfate proteoglycans of rat embryo fibroblasts. A hydrophobic form may link cytoskeleton and matrix components
    • Woods A., Couchman J.R. & Höök M. (1985) Heparan sulfate proteoglycans of rat embryo fibroblasts. A hydrophobic form may link cytoskeleton and matrix components. J. Biol. Chem. 260, 10872-10879.
    • (1985) J. Biol. Chem. , vol.260 , pp. 10872-10879
    • Woods, A.1    Couchman, J.R.2    Höök, M.3
  • 79
    • 84856234082 scopus 로고    scopus 로고
    • Syndecan-1 displays a protective role in aortic aneurysm formation by modulating T cell-mediated responses
    • Xiao J., Angsana J., Wen J. et al. (2012) Syndecan-1 displays a protective role in aortic aneurysm formation by modulating T cell-mediated responses. Arterioscler. Thromb. Vasc. Biol. 32, 386-396.
    • (2012) Arterioscler. Thromb. Vasc. Biol. , vol.32 , pp. 386-396
    • Xiao, J.1    Angsana, J.2    Wen, J.3
  • 80
    • 84862874555 scopus 로고    scopus 로고
    • Syndecan-4 over-expression preserves cardiac function in a rat model of myocardial infarction
    • Xie J., Wang J., Li R. et al. (2012) Syndecan-4 over-expression preserves cardiac function in a rat model of myocardial infarction. J. Mol. Cell. Cardiol. 53, 250-258.
    • (2012) J. Mol. Cell. Cardiol. , vol.53 , pp. 250-258
    • Xie, J.1    Wang, J.2    Li, R.3
  • 81
    • 0037100282 scopus 로고    scopus 로고
    • Soluble syndecan-1 promotes growth of myeloma tumors in vivo
    • Yang Y., Yaccoby S., Liu W. et al. (2002) Soluble syndecan-1 promotes growth of myeloma tumors in vivo. Blood 100, 610-617.
    • (2002) Blood , vol.100 , pp. 610-617
    • Yang, Y.1    Yaccoby, S.2    Liu, W.3
  • 82
    • 84886063101 scopus 로고    scopus 로고
    • Syndecan-1, a cell surface proteoglycan, negatively regulates initial leukocyte recruitment to the brain across the choroid plexus in murine experimental autoimmune encephalomyelitis
    • Zhang X., Wu C., Song J., Götte M. & Sorokin L. (2013) Syndecan-1, a cell surface proteoglycan, negatively regulates initial leukocyte recruitment to the brain across the choroid plexus in murine experimental autoimmune encephalomyelitis. J. Immunol. 191, 4551-4561.
    • (2013) J. Immunol. , vol.191 , pp. 4551-4561
    • Zhang, X.1    Wu, C.2    Song, J.3    Götte, M.4    Sorokin, L.5
  • 83
    • 24144482654 scopus 로고    scopus 로고
    • Syndecan recycling is controlled by syntenin-PIP2 interaction and Arf6
    • Zimmermann P., Zhang Z., Degeest G. et al. (2005) Syndecan recycling is controlled by syntenin-PIP2 interaction and Arf6. Dev. Cell 9, 377-388.
    • (2005) Dev. Cell , vol.9 , pp. 377-388
    • Zimmermann, P.1    Zhang, Z.2    Degeest, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.