Glypican-3: A marker and a therapeutic target in hepatocellular carcinoma

FEBS Journal

Volumn 280, Issue 10, 2013, Pages 2471-2476

  Filmus, Jorge ^a,b   Capurro, Mariana ^a,b  

^a Sunnybrook Health Sciences Centre   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

glypican 3; hepatocellular carcinoma; immunotherapy; tumor marker; Wnt signaling

Indexed keywords

ALPHA FETOPROTEIN; FRIZZLED PROTEIN; GLYPICAN 3; GLYPICAN 3 PEPTIDE VACCINE; MESSENGER RNA; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY GC33; PEPTIDE VACCINE; UNCLASSIFIED DRUG; WNT PROTEIN;

ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; CANCER GROWTH; CANCER IMMUNIZATION; CANCER INHIBITION; CELL SURFACE; CYTOTOXIC T LYMPHOCYTE; DRUG TOLERABILITY; GENE EXPRESSION; HUMAN; IMMUNOHISTOCHEMISTRY; LIVER BIOPSY; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER TUMOR; NONHUMAN; OVERALL SURVIVAL; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INTERACTION; RECEPTOR BINDING; REVIEW; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT;

ANTIBODIES, MONOCLONAL, HUMANIZED; CARCINOMA, HEPATOCELLULAR; CLINICAL TRIALS AS TOPIC; DISEASE PROGRESSION; FRIZZLED RECEPTORS; GLYPICANS; HUMANS; LIVER; MULTIPROTEIN COMPLEXES; PROTEIN BINDING; T-LYMPHOCYTES, CYTOTOXIC; TUMOR MARKERS, BIOLOGICAL; WNT SIGNALING PATHWAY;

EID: 84877686831     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12126     Document Type: Review

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