BALB/c and C57BL6 mouse strains vary in their ability to heal corneal epithelial debridement wounds

Experimental Eye Research

Volumn 87, Issue 5, 2008, Pages 478-486

  Pal Ghosh, Sonali ^a   Tadvalkar, Gauri ^a   Jurjus, Rosalyn A ^a   Zieske, James D ^b   Stepp, Mary Ann ^a  

^a GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

^b SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

corneal epithelium; mouse strains; recurrent erosions; stem cell deficiency; syndecan 1; wound healing

Indexed keywords

BROXURIDINE; CYTOKERATIN 8 ANTIBODY; CYTOKERATIN ANTIBODY; MUCIN 5AC ANTIBODY; PROPIDIUM IODIDE; PROTEIN ANTIBODY; SYNDECAN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; CELL COUNT; CELL MIGRATION; CELL PROLIFERATION; CONJUNCTIVA; CONTROLLED STUDY; CORNEA ENDOTHELIUM; CORNEA EROSION; ENUCLEATION; EPITHELIZATION; GENOTYPE; GOBLET CELL; IN VITRO STUDY; IN VIVO STUDY; KERATINOCYTE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; RECURRENT DISEASE; SPECIES COMPARISON; STAINING; STEM CELL; WOUND HEALING;

ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CORNEAL ULCER; DEBRIDEMENT; EPITHELIUM, CORNEAL; GENOTYPE; KERATINOCYTES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; RECURRENCE; SPECIES SPECIFICITY; STEM CELLS; TIME FACTORS; WOUND HEALING;

EID: 54249090199     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2008.08.013     Document Type: Article

References (38)

1. Adriouch S., Dox C., Welge V., Seman M., Koch-Nolte F., and Haag F. Cutting edge: a natural P451L mutation in the cytoplasmic domain impairs the function of the mouse P2X7 receptor. J. Immunol. 169 (2002) 4108-4112
2. Angel J.M., and DiGiovanni J. Genetics of skin tumor promotion. Prog. Exp. Tumor Res. 35 (1999) 143-157
3. Avunduk A.M., and Tekelioglu Y. Therapeutic use of limbal stem cells. Curr. Stem Cell Res. Ther. 1 (2006) 231-238
4. Beckwith J., Cong Y., Sundberg J.P., Elson C.O., and Leiter E.H. Cdcs1, a major colitogenic locus in mice, regulates innate and adaptive immune response to enteric bacterial antigens. Gastroenterology 129 (2005) 1473-1484
5. Cardoso J.F., Souza B.R., Amadeu T.P., Valença S.S., Porto L.C., and Costa A.M. Effects of cigarette smoke in mice wound healing is strain dependent. Toxicol. Pathol. 35 (2007) 890-896
6. Chikama T., Wakuta M., Liu Y., and Nishida T. Deviated mechanism of wound healing in diabetic corneas. Cornea 26 (2007) S75-S81
7. Dlugosz A.A., Glick A.B., Tennenbaum T., Weinberg W.C., and Yuspa S.H. Isolation and utilization of epidermal keratinocytes for oncogene research. Methods Enzymol. 254 (1995) 3-20
8. Erway L.C., Shiau Y.W., Davis R.R., and Krieg E.F. Genetics of age-related hearing loss in mice. III. Susceptibility of inbred and F1 hybrid strains to noise-induced hearing loss. Hear Res. 93 (1996) 181-187
9. Gu B.J., Zhang W., Worthington A., Sluyter R., Dao-Ung P., Petrou S., Barden J.A., and Wiley J.S. A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor. J. Biol. Chem. 276 (2001) 11135-11142
10. Grueterich M., Espana E.M., and Tseng S.C. Ex vivo expansion of limbal epithelial stem cells: amniotic membrane serving as a stem cell niche. Surv. Ophthalmol. 48 (2003) 631-646
11. Hahn W.C., and Weinberg R.A. Rules for making human tumor cells. N. Engl. J. Med. 347 (2002) 1593-1603
12. Hayashi R., Yamato M., Sugiyama H., Sumide T., Yang J., Okano T., Tano Y., and Nishida K. N-Cadherin is expressed by putative stem/progenitor cells and melanocytes in the human limbal epithelial stem cell niche. Stem Cells 25 (2007) 289-296
13. Jurjus R.A., Liu Y., Pal-Ghosh S., Tadvalkar G., and Stepp M.A. Primary dermal fibroblasts derived from sdc-1 deficient mice migrate faster and have altered integrin function. Wound Repair Regen. 16 (2008) 650-661
14. Kazmierczak P., Sakaguchi H., Tokita J., Wilson-Kubalek E.M., Milligan R.A., Müller U., and Kachar B. Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells. Nature 449 (2007) 87-91
15. Kenyon K.R. Amniotic membrane: mother's own remedy for ocular surface disease. Cornea 24 (2005) 639-642
16. Mayo C., Ren R., Rich C., Stepp M.A., and Trinkaus-Randall V. Regulation by P2X7: epithelial migration and stromal organization in the cornea. Invest. Ophthalmol. Vis. Sci. (2008) (e pub ahead of print, May 23)
17. Mock B.A., Lowry D.T., Rehman I., Padlan C., Yuspa S.H., and Hennings H. Multigenic control of skin tumor susceptibility in SENCARA/Pt mice. Carcinogenesis 19 (1998) 1109-1115
18. Pajoohesh-Ganji A., Pal-Ghosh S., Simmens S.J., and Stepp M.A. Integrins in slow-cycling corneal epithelial cells at the limbus in the mouse. Stem Cells 24 (2006) 1075-1086
19. Pajoohesh-Ganji A., and Stepp M.A. In search of markers for the stem cells of the corneal epithelium. Biol. Cell 97 (2005) 265-276
20. Pal-Ghosh S., Pajoohesh-Ganji A., Brown M., and Stepp M.A. A mouse model for the study of recurrent corneal epithelial erosions: α9β1 integrin implicated in progression of the disease. Invest. Ophthalmol. Vis. Sci. 45 (2004) 1775-1788
21. Ramamurthi S., Rahman M.Q., Dutton G.N., and Ramaesh K. Pathogenesis, clinical features and management of recurrent corneal erosions. Eye 20 (2006) 635-644
22. Sangwan V.S., Burman S., Tejwani S., Mahesh S.P., and Murthy R. Amniotic membrane transplantation: a review of current indications in the management of ophthalmic disorders. Indian J. Ophthalmol. 55 (2007) 251-260
23. Schultz R.O., Van Horn D.L., Peters M.A., Klewin K.M., and Schutten W.H. Diabetic keratopathy. Trans. Am. Ophthalmol. Soc. 79 (1981) 180-199
24. Schwartz G.S., and Holland E.J. Iatrogenic limbal stem cell deficiency: when glaucoma management contributes to corneal disease. J. Glaucoma 10 (2001) 443-445
25. Singh, P., Chen, C., Pal-Ghosh, S., Stepp, M.A., Sheppard, D, Van De Water, L. (2008). Loss of α9β1 integrin causes cell proliferation and reepithelialization defects during wound healing. J. Invest. Derm. (epub online July 17).
26. Stepp M.A., Gibson H.E., Gala P.H., Iglesia D.D., Pajoohesh-Ganji A., Pal-Ghosh S., Brown M., Aquino C., Schwartz A.M., Goldberger O., Hinkes M.T., and Bernfield M. Defects in keratinocyte activation during wound healing in the syndecan-1-deficient mouse. J. Cell Sci. 115 (2002) 4517-4531
27. Stepp M.A., Liu Y., Pal-Ghosh S., Jurjus R.A., Tadvalkar G., Sekaran A., Losicco K., Jiang L., Larsen M., Li L., and Yuspa S.H. Reduced migration, altered matrix and enhanced TGFβ1 signaling are signatures of mouse keratinocytes lacking Sdc1. J. Cell Sci. 120 (2007) 2851-2863
28. Stepp M.A., Spurr-Michaud S., Tisdale A., Elwell J., and Gipson I.K. α6β4 integrin heterodimer is a component of hemidesmosomes. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 8970-8974
29. Stepp M.A., and Zieske J.D. The corneal epithelial stem cell niche. Ocul. Surf. 3 (2005) 15-26
30. Stramer B.M., Zieske J.D., Jung J.C., Austin J.S., and Fini M.E. Molecular mechanisms controlling the fibrotic repair phenotype in cornea: implications for surgical outcomes. Invest. Ophthalmol. Vis. Sci. 44 (2003) 4237-4246
31. Tylzanowski P., Mebis L., and Luyten F.P. The Noggin null mouse phenotype is strain dependent and haploinsufficiency leads to skeletal defects. Dev. Dyn. 235 (2006) 1599-1607
32. Waterston R.H., et al., Mouse genome sequencing consortium. Initial sequencing and comparative analysis of the mouse genome. Nature 420 (2002) 520-562
33. Whitcher J.P., Srinivasan M., and Upadhyay M.P. Corneal blindness: a global perspective. Bull. World Health Organ. 79 (2001) 214-221
34. Wiley J.S., Dao-Ung L.P., Gu B.J., Sluyter R., Shemon A.N., Li C., Taper J., Gallo J., and Manoharan A. A loss-of-function polymorphic mutation in the cytolytic P2X7 receptor gene and chronic lymphocytic leukaemia: a molecular study. Lancet 359 (2002) 1114-1119
35. Woodworth C.D., Michael E., Smith L., Vijayachandra K., Glick A., Hennings H., and Yuspa S.H. Strain-dependent differences in malignant conversion of mouse skin tumors is an inherent property of the epidermal keratinocyte. Carcinogenesis 25 (2004) 1771-1778
36. Zhang J., Niu C., Ye L., Huang H., He X., Tong W.G., Ross J., Haug J., Johnson T., Feng J.Q., Harris S., Wiedemann L.M., Mishina Y., and Li L. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425 (2003) 836-841
37. Zhang Y. Animal models of inflammatory spinal and sacroiliac joint diseases. Rheum. Dis. Clin. North Am. 29 (2003) 631-645
38. Zieske J.D., Hutcheon A.E., Guo X., Chung E.H., and Joyce N.C. TGF-β receptor types I and II are differentially expressed during corneal epithelial wound repair. Invest. Ophthalmol. Vis. Sci. 42 (2001) 1465-1471