Hybrid [FeFe]-hydrogenases with modified active sites show remarkable residual enzymatic activity

Biochemistry

Volumn 54, Issue 7, 2015, Pages 1474-1483

  Siebel, Judith F ^a   Adamska Venkatesh, Agnieszka ^a   Weber, Katharina ^a   Rumpel, Sigrun ^a   Reijerse, Edward ^a   Lubitz, Wolfgang ^a  

^a MAX PLANCK INSTITUTE FOR CHEMICAL ENERGY CONVERSION   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST ACTIVITY; ENZYMES; FOURIER TRANSFORM INFRARED SPECTROSCOPY; HYDROGEN; HYDROGEN BONDS; LIGANDS;

AMINE MOIETIES; CONFORMATIONAL FLEXIBILITY; ENZYMATIC ACTIVITIES; HYDROGEN OXIDATION; NATIVE ENZYMES; PROTON REDUCTION; RESIDUAL ACTIVITY; [FEFE]HYDROGENASES;

ENZYME ACTIVITY;

CARBON DIOXIDE; CARBONYL DERIVATIVE; CYANIDE; DITHIOL DERIVATIVE; HYDROGEN; HYDROGENASE; IRON DERIVATIVE; LIGAND; PROTON; HETEROCYCLIC COMPOUND; PROPANE; PROPANEDITHIOLATE; THIOL DERIVATIVE;

ARTICLE; BIOCATALYSIS; CALCULATION; CHEMICAL BINDING; CHEMICAL PARAMETERS; CONFORMATION; CRYSTAL STRUCTURE; DENSITY FUNCTIONAL THEORY; ENZYME ACTIVITY; GENE INSERTION; HYDROGEN BOND; INFRARED SPECTROSCOPY; LIMIT OF DETECTION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; REDUCTION; STATIC ELECTRICITY; SURFACE PROPERTY; ANALOGS AND DERIVATIVES; CHEMICAL STRUCTURE; CHEMISTRY; CHLAMYDOMONAS REINHARDTII; ENZYME ACTIVE SITE; ENZYMOLOGY; METABOLISM; METHYLATION; OXIDATION REDUCTION REACTION;

AZA COMPOUNDS; CATALYTIC DOMAIN; CHLAMYDOMONAS REINHARDTII; HYDROGEN; HYDROGENASE; IRON COMPOUNDS; LIGANDS; METHYLATION; MODELS, MOLECULAR; OXIDATION-REDUCTION; PROPANE; SULFHYDRYL COMPOUNDS;

EID: 84923369381     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi501391d     Document Type: Article

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