Inhibition of LINGO-1 promotes functional recovery after experimental spinal cord demyelination

Experimental Neurology

Volumn 266, Issue , 2015, Pages 68-73

  Zhang, Yongjie ^a   Zhang, Yi Ping ^b   Pepinsky, Blake ^c   Huang, Guanrong ^c   Shields, Lisa B E ^b   Shields, Christopher B ^b   Mi, Sha ^c  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Norton Healthcare   (United States)

^c BIOGEN   (United States)

Author keywords

Demyelination; Electrophysiology; LINGO 1; Lysolecithin model; Morphometry; Multiple sclerosis; TcMMEP

Indexed keywords

GLYCOPROTEIN; IMMUNOGLOBULIN G; LEUCINE RICH REPEAT AND IMMUNOGLOBULIN DOMAIN CONTAINING NOGO RECEPTOR INTERACTING PROTEIN 1; LYSOPHOSPHATIDYLCHOLINE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 3B5; TOLUIDINE DERIVATIVE; UNCLASSIFIED DRUG; LINGO1 PROTEIN, MOUSE; MEMBRANE PROTEIN; NERVE PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DEMYELINATION; FEMALE; IN VIVO STUDY; LATENT PERIOD; MAGNETIC STIMULATION; MORPHOMETRICS; MOUSE; MULTIPLE SCLEROSIS; NERVE FUNCTION; NERVE REGENERATION; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REMYELINIZATION; SPINAL CORD DEMYELINATION; SPINAL CORD POTENTIAL; SPINAL NERVE; TRANSCRANIAL MAGNETIC MOTOR EVOKED POTENTIAL; VENTROLATERAL FUNICULUS; WILD TYPE; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CHEMICALLY INDUCED; CONVALESCENCE; DEMYELINATING AUTOIMMUNE DISEASES, CNS; DRUG EFFECTS; EVOKED MUSCLE RESPONSE; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MYELIN SHEATH; PATHOLOGY; SPINAL ROOT;

ANIMALS; ANTIBODIES, MONOCLONAL; DEMYELINATING AUTOIMMUNE DISEASES, CNS; EVOKED POTENTIALS, MOTOR; FEMALE; IMMUNOGLOBULIN G; LYSOPHOSPHATIDYLCHOLINES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELIN SHEATH; NERVE TISSUE PROTEINS; RECOVERY OF FUNCTION; SPINAL NERVE ROOTS;

EID: 84923364387     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2015.02.006     Document Type: Article

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