메뉴 건너뛰기




Volumn 24, Issue 32, 2004, Pages 7140-7149

Signaling from integrins to Fyn to Rho family GTPases regulates morphologic differentiation of oligodendrocytes

Author keywords

Fyn; Integrins; Kinase; Myelination; Oligodendrocyte; RhoA; Signaling

Indexed keywords

INTEGRIN; MYELIN BASIC PROTEIN; PROTEIN CDC42; PROTEIN KINASE FYN; RAC1 PROTEIN; RHO FACTOR; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 4143050338     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5319-03.2004     Document Type: Article
Times cited : (219)

References (48)
  • 1
    • 0035158377 scopus 로고    scopus 로고
    • RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity
    • Arthur WT, Burridge K (2001) RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity. Mol Biol Cell 12:2711-2720.
    • (2001) Mol Biol Cell , vol.12 , pp. 2711-2720
    • Arthur, W.T.1    Burridge, K.2
  • 2
    • 0028872351 scopus 로고
    • The effect of oncogenes on the growth and differentiation of oligodendrocyte type 2 astrocyte progenitor cells
    • Barnett SC, Crouch DH (1995) The effect of oncogenes on the growth and differentiation of oligodendrocyte type 2 astrocyte progenitor cells. Cell Growth Differ 6:69-80.
    • (1995) Cell Growth Differ , vol.6 , pp. 69-80
    • Barnett, S.C.1    Crouch, D.H.2
  • 3
    • 0037113091 scopus 로고    scopus 로고
    • The integrin beta tail is required and sufficient to regulate adhesion signaling to Rac1
    • Berrier AL, Martinez R, Bokoch GM, LaFlamme SE (2002) The integrin beta tail is required and sufficient to regulate adhesion signaling to Rac1. J Cell Sci 115:4285-4291.
    • (2002) J Cell Sci , vol.115 , pp. 4285-4291
    • Berrier, A.L.1    Martinez, R.2    Bokoch, G.M.3    LaFlamme, S.E.4
  • 4
    • 0034070935 scopus 로고    scopus 로고
    • The regulation of proliferation and differentiation in oligodendrocyte progenitor cells by alphaV integrins
    • Blaschuk KL, Frost EE, ffrench-Constant C (2000) The regulation of proliferation and differentiation in oligodendrocyte progenitor cells by alphaV integrins. Development 127:1961-1969.
    • (2000) Development , vol.127 , pp. 1961-1969
    • Blaschuk, K.L.1    Frost, E.E.2    Ffrench-Constant, C.3
  • 6
    • 0035071323 scopus 로고    scopus 로고
    • p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation
    • Brouns MR, Matheson SF, Settleman J (2001) p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation. Nat Cell Biol 3:361-367.
    • (2001) Nat Cell Biol , vol.3 , pp. 361-367
    • Brouns, M.R.1    Matheson, S.F.2    Settleman, J.3
  • 7
    • 0032861273 scopus 로고    scopus 로고
    • Laminin-2/integrin interactions enhance myelin membrane formation by oligodendrocytes
    • Buttery PC, ffrench-Constant C (1999) Laminin-2/integrin interactions enhance myelin membrane formation by oligodendrocytes. Mol Cell Neurosci 14:199-212.
    • (1999) Mol Cell Neurosci , vol.14 , pp. 199-212
    • Buttery, P.C.1    Ffrench-Constant, C.2
  • 8
    • 0032825266 scopus 로고    scopus 로고
    • Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells
    • Cheresh DA, Leng J, Klemke RL (1999) Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells. J Cell Biol 146:1107-1116.
    • (1999) J Cell Biol , vol.146 , pp. 1107-1116
    • Cheresh, D.A.1    Leng, J.2    Klemke, R.L.3
  • 9
    • 0034685772 scopus 로고    scopus 로고
    • Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding
    • Das B, Shu X, Day GJ, Han J, Krishna UM, Falck JR, Broek D (2000) Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding. J Biol Chem 275:15074-15081.
    • (2000) J Biol Chem , vol.275 , pp. 15074-15081
    • Das, B.1    Shu, X.2    Day, G.J.3    Han, J.4    Krishna, U.M.5    Falck, J.R.6    Broek, D.7
  • 10
    • 0034595381 scopus 로고    scopus 로고
    • Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK
    • del Pozo MA, Price LS, Alderson NB, Ren XD, Schwartz MA (2000) Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK. EMBO J 19:2008-2014.
    • (2000) EMBO J , vol.19 , pp. 2008-2014
    • Del Pozo, M.A.1    Price, L.S.2    Alderson, N.B.3    Ren, X.D.4    Schwartz, M.A.5
  • 11
    • 0033175564 scopus 로고    scopus 로고
    • Selective regulation of integrin-cytoskeleton interactions by the tyrosine kinase Src
    • Felsenfeld DP, Schwartzberg PL, Venegas A, Tse R, Sheetz MP (1999) Selective regulation of integrin-cytoskeleton interactions by the tyrosine kinase Src. Nat Cell Biol 1:200-206.
    • (1999) Nat Cell Biol , vol.1 , pp. 200-206
    • Felsenfeld, D.P.1    Schwartzberg, P.L.2    Venegas, A.3    Tse, R.4    Sheetz, M.P.5
  • 13
    • 0032576771 scopus 로고    scopus 로고
    • Axon guidance: GTPases help axons reach their targets
    • Gallo G, Letourneau PC (1998) Axon guidance: GTPases help axons reach their targets. Curr Biol 8:R80-R82.
    • (1998) Curr Biol , vol.8
    • Gallo, G.1    Letourneau, P.C.2
  • 14
    • 0028021308 scopus 로고
    • Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho
    • Jalink K, van Corven EJ, Hengeveld T, Morii N, Narumiya S, Moolenaar WH (1994) Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. J Cell Biol 126:801-810.
    • (1994) J Cell Biol , vol.126 , pp. 801-810
    • Jalink, K.1    Van Corven, E.J.2    Hengeveld, T.3    Morii, N.4    Narumiya, S.5    Moolenaar, W.H.6
  • 16
    • 0036469248 scopus 로고    scopus 로고
    • Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau
    • Klein C, Kramer EM, Cardine AM, Schraven B, Brandt R, Trotter J (2002) Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau. J Neurosci 22:698-707.
    • (2002) J Neurosci , vol.22 , pp. 698-707
    • Klein, C.1    Kramer, E.M.2    Cardine, A.M.3    Schraven, B.4    Brandt, R.5    Trotter, J.6
  • 18
    • 0028986034 scopus 로고
    • The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts
    • Kozma R, Ahmed S, Best A, Lim L (1995) The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts. Mol Cell Biol 15:1942-1952.
    • (1995) Mol Cell Biol , vol.15 , pp. 1942-1952
    • Kozma, R.1    Ahmed, S.2    Best, A.3    Lim, L.4
  • 19
    • 0031027205 scopus 로고    scopus 로고
    • Rho family GTPases and neuronal growth cone remodelling: Relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid
    • Kozma R, Sarner S, Ahmed S, Lim L (1997) Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid. Mol Cell Biol 17:1201-1211.
    • (1997) Mol Cell Biol , vol.17 , pp. 1201-1211
    • Kozma, R.1    Sarner, S.2    Ahmed, S.3    Lim, L.4
  • 20
    • 0038933866 scopus 로고    scopus 로고
    • Compartmentation of Fyn kinase with glycosylphosphatidylinositol-anchored molecules in oligodendrocytes facilitates kinase activation during myelination
    • Kramer EM, Klein C, Koch T, Boytinck M, Trotter J (1999) Compartmentation of Fyn kinase with glycosylphosphatidylinositol-anchored molecules in oligodendrocytes facilitates kinase activation during myelination. J Biol Chem 274:29042-29049.
    • (1999) J Biol Chem , vol.274 , pp. 29042-29049
    • Kramer, E.M.1    Klein, C.2    Koch, T.3    Boytinck, M.4    Trotter, J.5
  • 21
    • 0035903208 scopus 로고    scopus 로고
    • Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction
    • Liang X, Nazarian A, Erdjument-Bromage H, Bornmann W, Tempst P, Resh MD (2001) Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction. J Biol Chem 276:30987-30994.
    • (2001) J Biol Chem , vol.276 , pp. 30987-30994
    • Liang, X.1    Nazarian, A.2    Erdjument-Bromage, H.3    Bornmann, W.4    Tempst, P.5    Resh, M.D.6
  • 22
    • 0037186083 scopus 로고    scopus 로고
    • Regulation of rho GTPases by cross talk and neuronal activity in vivo
    • Li Z, Aizenman CD, Cline HT (2002) Regulation of rho GTPases by cross talk and neuronal activity in vivo. Neuron 33:741-750.
    • (2002) Neuron , vol.33 , pp. 741-750
    • Li, Z.1    Aizenman, C.D.2    Cline, H.T.3
  • 23
    • 1242272132 scopus 로고    scopus 로고
    • Phospholipids can switch the GTPase substrate preference of a GTPase activating protein
    • Ligeti E, Dagher M-C, Hernande SE, Koleske AJ, Settleman J (2004) Phospholipids can switch the GTPase substrate preference of a GTPase activating protein. J Biol Chem 279:5055-5058.
    • (2004) J Biol Chem , vol.279 , pp. 5055-5058
    • Ligeti, E.1    Dagher, M.-C.2    Hernande, S.E.3    Koleske, A.J.4    Settleman, J.5
  • 24
    • 0028176151 scopus 로고
    • Expression of a beta 1-related integrin by oligodendroglia in primary culture: Evidence for a functional role in myelination
    • Malek-Hedayat S, Rome LH (1994) Expression of a beta 1-related integrin by oligodendroglia in primary culture: evidence for a functional role in myelination. J Cell Biol 124:1039-1046.
    • (1994) J Cell Biol , vol.124 , pp. 1039-1046
    • Malek-Hedayat, S.1    Rome, L.H.2
  • 25
    • 0028078824 scopus 로고
    • A brain serine/threonine protein kinase activated by Cdc42 and Rac1
    • Manser E, Leung T, Salihuddin H, Zhao ZS, Lim L (1994) A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature 367:40-46.
    • (1994) Nature , vol.367 , pp. 40-46
    • Manser, E.1    Leung, T.2    Salihuddin, H.3    Zhao, Z.S.4    Lim, L.5
  • 26
    • 0027986830 scopus 로고
    • A Developmental analysis of oligodendroglial integrins in primary cells: Changes in αv-associated β subunits during differentiation
    • Milner R, Ffrench-Constant C (1994) A Developmental analysis of oligodendroglial integrins in primary cells: changes in αv-associated β subunits during differentiation. Development 120:3497-3506.
    • (1994) Development , vol.120 , pp. 3497-3506
    • Milner, R.1    Ffrench-Constant, C.2
  • 28
    • 0028961293 scopus 로고
    • Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
    • Nobes CD, Hall A (1995) Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81:53-62.
    • (1995) Cell , vol.81 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 29
    • 0033553885 scopus 로고    scopus 로고
    • Morphological differentiation of oligodendrocytes requires activation of Fyn tyrosine kinase
    • Osterhout DJ, Wolven A, Wolf RM, Resh MD, Chao MV (1999) Morphological differentiation of oligodendrocytes requires activation of Fyn tyrosine kinase. J Cell Biol 145:1209-1218.
    • (1999) J Cell Biol , vol.145 , pp. 1209-1218
    • Osterhout, D.J.1    Wolven, A.2    Wolf, R.M.3    Resh, M.D.4    Chao, M.V.5
  • 30
    • 0031844821 scopus 로고    scopus 로고
    • Activation of Rac and Cdc42 by integrins mediates cell spreading
    • Price LS, Leng J, Schwartz MA, Bokoch GM (1998) Activation of Rac and Cdc42 by integrins mediates cell spreading. Mol Biol Cell 9:1863-1871.
    • (1998) Mol Biol Cell , vol.9 , pp. 1863-1871
    • Price, L.S.1    Leng, J.2    Schwartz, M.A.3    Bokoch, G.M.4
  • 31
    • 0035838420 scopus 로고    scopus 로고
    • Expression of dominant-negative and chimeric subunits reveals an essential role for beta 1 integrin during myelination
    • Relvas JB, Setzu A, Baron W, Buttery PC, LaFlamme SE, Franklin RJ, ffrench-Constant C (2001) Expression of dominant-negative and chimeric subunits reveals an essential role for beta 1 integrin during myelination. Curr Biol 11:1039-1043.
    • (2001) Curr Biol , vol.11 , pp. 1039-1043
    • Relvas, J.B.1    Setzu, A.2    Baron, W.3    Buttery, P.C.4    LaFlamme, S.E.5    Franklin, R.J.6    Ffrench-Constant, C.7
  • 32
    • 0033081753 scopus 로고    scopus 로고
    • Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
    • Ren XD, Kiosses WB, Schwartz MA (1999) Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J 18:578-585.
    • (1999) EMBO J , vol.18 , pp. 578-585
    • Ren, X.D.1    Kiosses, W.B.2    Schwartz, M.A.3
  • 33
    • 0026654125 scopus 로고
    • The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
    • Ridley AJ, Paterson HF, Johnston CL, Diekmann D, Hall A (1992) The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70:401-410.
    • (1992) Cell , vol.70 , pp. 401-410
    • Ridley, A.J.1    Paterson, H.F.2    Johnston, C.L.3    Diekmann, D.4    Hall, A.5
  • 34
    • 0027441940 scopus 로고
    • Rho family GTPase activating proteins p190, bcr and rhoGAP show distinct specificities in vitro and in vivo
    • Ridley AJ, Self AJ, Kasmi F, Paterson HF, Hall A, Marshall CJ, Ellis C (1993) rho family GTPase activating proteins p190, bcr and rhoGAP show distinct specificities in vitro and in vivo. EMBO J 12:5151-5160.
    • (1993) EMBO J , vol.12 , pp. 5151-5160
    • Ridley, A.J.1    Self, A.J.2    Kasmi, F.3    Paterson, H.F.4    Hall, A.5    Marshall, C.J.6    Ellis, C.7
  • 35
    • 0033615966 scopus 로고    scopus 로고
    • Rac downregulates Rho activity: Reciprocal balance between both GTPases determines cellular morphology and migratory behavior
    • Sander EE, ten Klooster JP, van Delft S, van der Kammen RA, Collard JG (1999) Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J Cell Biol 147:1009-1022.
    • (1999) J Cell Biol , vol.147 , pp. 1009-1022
    • Sander, E.E.1    Ten Klooster, J.P.2    Van Delft, S.3    Van Der Kammen, R.A.4    Collard, J.G.5
  • 36
    • 0032859988 scopus 로고    scopus 로고
    • Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases
    • Schaller MD, Hildebrand JD, Parsons JT (1999) Complex formation with focal adhesion kinase: a mechanism to regulate activity and subcellular localization of Src kinases. Mol Biol Cell 10:3489-3505.
    • (1999) Mol Biol Cell , vol.10 , pp. 3489-3505
    • Schaller, M.D.1    Hildebrand, J.D.2    Parsons, J.T.3
  • 37
    • 0031032777 scopus 로고    scopus 로고
    • Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: Involvement of the Grb2, p130cas, and Nck adaptor proteins
    • Schlaepfer DD, Broome MA, Hunter T (1997) Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins. Mol Cell Biol 17:1702-1713.
    • (1997) Mol Cell Biol , vol.17 , pp. 1702-1713
    • Schlaepfer, D.D.1    Broome, M.A.2    Hunter, T.3
  • 38
    • 0035575458 scopus 로고    scopus 로고
    • Integrin signaling revisited
    • Schwartz MA (2001) Integrin signaling revisited. Trends Cell Biol 11:466-470.
    • (2001) Trends Cell Biol , vol.11 , pp. 466-470
    • Schwartz, M.A.1
  • 39
    • 0026668762 scopus 로고
    • Association between GTPase activators for Rho and Ras families
    • Settleman J, Albright CF, Foster LC, Weinberg RA (1992) Association between GTPase activators for Rho and Ras families. Nature 359:153-154.
    • (1992) Nature , vol.359 , pp. 153-154
    • Settleman, J.1    Albright, C.F.2    Foster, L.C.3    Weinberg, R.A.4
  • 40
    • 0035866046 scopus 로고    scopus 로고
    • Fyn tyrosine kinase regulates oligodendroglial cell development but is not required for morphological differentiation of oligodendrocytes
    • Sperber BR, McMorris FA (2001) Fyn tyrosine kinase regulates oligodendroglial cell development but is not required for morphological differentiation of oligodendrocytes. J Neurosci Res 63:303-312.
    • (2001) J Neurosci Res , vol.63 , pp. 303-312
    • Sperber, B.R.1    McMorris, F.A.2
  • 43
    • 0033807686 scopus 로고    scopus 로고
    • Regulation of dendritic spine morphology by the rho family of small GTPases: Antagonistic roles of Rac and Rho
    • Tashiro A, Minden A, Yuste R (2000) Regulation of dendritic spine morphology by the rho family of small GTPases: antagonistic roles of Rac and Rho. Cereb Cortex 10:927-938.
    • (2000) Cereb Cortex , vol.10 , pp. 927-938
    • Tashiro, A.1    Minden, A.2    Yuste, R.3
  • 45
    • 84866476582 scopus 로고    scopus 로고
    • Rapid plasma membrane anchoring of newly synthesized p59fyn: Selective requirement for NH2-terminal myristoylation and palmitoylation at cysteine-3
    • van't Hof W, Resh MD (1997) Rapid plasma membrane anchoring of newly synthesized p59fyn: selective requirement for NH2-terminal myristoylation and palmitoylation at cysteine-3. J Cell Biol 136:1023-1035.
    • (1997) J Cell Biol , vol.136 , pp. 1023-1035
    • Van't Hof, W.1    Resh, M.D.2
  • 46
    • 0032483575 scopus 로고    scopus 로고
    • A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth
    • Wary KK, Mariotti A, Zurzolo C, Giancotti FG (1998) A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth. Cell 94:625-634.
    • (1998) Cell , vol.94 , pp. 625-634
    • Wary, K.K.1    Mariotti, A.2    Zurzolo, C.3    Giancotti, F.G.4
  • 47
    • 0034858207 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of p190 RhoGAP by Fyn regulates oligodendrocyte differentiation
    • Wolf RM, Wilkes JJ, Chao MV, Resh MD (2001) Tyrosine phosphorylation of p190 RhoGAP by Fyn regulates oligodendrocyte differentiation. J Neurobiol 49:62-78.
    • (2001) J Neurobiol , vol.49 , pp. 62-78
    • Wolf, R.M.1    Wilkes, J.J.2    Chao, M.V.3    Resh, M.D.4
  • 48
    • 0034235662 scopus 로고    scopus 로고
    • Rapid dendritic remodeling in the developing retina: Dependence on neurotransmission and reciprocal regulation by Rac and Rho
    • Wong WT, Faulkner-Jones BE, Sanes JR, Wong RO (2000) Rapid dendritic remodeling in the developing retina: dependence on neurotransmission and reciprocal regulation by Rac and Rho. J Neurosci 20:5024-5036.
    • (2000) J Neurosci , vol.20 , pp. 5024-5036
    • Wong, W.T.1    Faulkner-Jones, B.E.2    Sanes, J.R.3    Wong, R.O.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.