Acceleration in the rate of CNS remyelination in lysolecithin-induced demyelination

Journal of Neuroscience

Volumn 18, Issue 7, 1998, Pages 2498-2505

  Pavelko, Kevin D ^a   Van Engelen, Baziel G M ^a,b   Rodriguez, Moses ^a  

^a MAYO CLINIC   (United States)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Autoantibodies; CNS; Corticoste roids; Demyelination; Immunoglobulin; Injury; Lysolecithin; Remyelination

Indexed keywords

IMMUNOGLOBULIN; METHYLPREDNISOLONE; METHYLPREDNISOLONE ACETATE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY SCH94 03; STEROID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEMYELINATION; DRUG EFFECT; HISTOPATHOLOGY; IMMUNOREGULATION; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATION; INTRAPERITONEAL DRUG ADMINISTRATION; MACROPHAGE; MOUSE; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; REMYELINIZATION; SCAVENGING SYSTEM; TRANSCRIPTION REGULATION;

EID: 0032053402     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-07-02498.1998     Document Type: Article

References (47)

1. Armstrong R, Friedrich Jr VL, Holmes KV, Dubois-Dalcq M (1990) In vitro analysis of the oligodendrocyte lineage in mice during demyelination and remyelination. J Cell Biol 111:1183-1195.
2. Arya SK, Wong-Staal F, Gallo RC (1984) Dexamethasone-mediated inhibition of human T-cell growth factor and gamma-interferon messenger RNA. J Immunol 133:273-276.
3. Asakura K, Miller DJ, Murray K, Bansal R, Pfeiffer SE, Rodriguez M (1996a) Monoclonal autoantibody SCH94.03 which promotes CNS remyelination recognizes an antigen on the surface of oligodendrocytes. J Neurosci Res 43:273-281.
4. Asakura K, Pogulis RJ, Pease LR, Rodriguez M (1996b) A monoclonal autoantibody which promotes central nervous system remyelination is highly polyreactive to multiple known and novel antigens. J Neuroimmunol 65:11-19.
5. Bansal R, Gard AL, Pfeiffer SE (1988) Stimulation of oligodendrocyte differentiation in culture by growth in the presence of a monoclonal antibody to sulfated glycolipid. J Neurosci Res 21:260-267.
6. Bartholdi D, Schwab ME (1995) Methylprednisolone inhibits early inflammatory processes but not ischemic cell death after experimental spinal cord lesion in rat. Brain Res 672:177-186.
7. Benveniste EN, Merrill JE (1986) Stimulation of oligodendroglial proliferation and maturation by interleukin-2. Nature 321:610-613.
8. Blakemore WF (1973) Demyelination in the superior cerebellar peduncle in the mouse induced by Cuprizone. J Neurol Sci 20:63-72.
9. Blakemore WF (1976) Invasion of Schwann cells into the spinal card of the rat following local injections of lysolecithin. Neuropath Appl Neurobiol 2:21-39.
10. Boumpas DT, Anastassiou ED, Older SA, Tsokos GC, Nelson DL, Balow JE (1991) Dexamethasone inhibits human interleukin 2 but not interleukin 2 receptor gene expression in vitro at the level of nuclear transcription. J Clin Invest 87:1739-1747.
11. Bracken MB, Shepard MJ, Collins WF, Holford TR, Young W, Baskin DS, Eisenberg HM, Flamm E, Leo-Summers L, Maroon J, Marshall LF, Perot Jr PL, Piepmeir J, Sonntag VKH, Wagner FC, Wilberger JE, Winn HR. (1990) A randomized controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. N Engl J Med 322:1405-1411.
12. +)-ATPase, lipid peroxidation, and alpha motor neuron function. J Neurosurg 56:838-844.
13. Carrol WM, Jennings AR (1994) Early recruitment of oligodendrocyte precursors in CNS demyelination. Brain 117:563-578.
14. Cohen JA, Williams WV, Geller HM, Greene MI (1991) Anti-reovirus receptor antibody accelerates expression of the optic nerve oligodendrocyte developmental program. Proc Natl Acad Sci USA 88:1266-1270.
15. Crompton MR, Moss SE, Crumpton MJ (1988) Diversity in the lipocortin/calpactin family. Cell 55:1-3.
16. Cupps TR, Fauci AS (1982) Corticosteroid mediated immunoregulation in man. Immunol Rev 65:133-155.
17. Fazekas F, Deisenhammer F, Strasser-Fuchs S, Nahler G, Mamoli B (1997) Randomised placebo-controlled trial of monthly intravenous immunoglobulin therapy in relapsing-remitting multiple sclerosis. Lancet 349:589-593.
18. Ghatak NR, Hirano A, Doron Y, Zimmerman HM (1973) Remyelination in multiple sclerosis with peripheral type myelin. Arch Neurol 29:262-267.
19. Gilson J, Blakemore WF (1993) Failure of remyelination in areas of demyelination produced in the spinal cord of old rats. Neuropathol Appl Neurobiol 19:173-181.
20. Gledhill RF, Harrison BM, McDonald WI (1973) Demyelination and remyelination after acute spinal cord compression. Exp Neurol 38:472-487.
21. Gronemeyer H (1992) Control of transcription activation by steroid hormone receptors. FASEB J 6:2524-2529.
22. Hall SM (1972) The effect of injections of lysophosphatidyl choline into white matter of the adult mouse spinal cord. J Cell Sci 13:257-277.
23. Herndon RM, Price DP, Weiner LP (1977) Regeneration of oligodendroglia during recovery from demyelinating disease. Science 195:693-694.
24. Hunter SF, Miller DJ, Rodriguez M (1997) Monoclonal remyelination-promoting natural autoantibody sch 94.03 -pharmacokinetics and in vivo targets within demyelinated spinal cord in a mouse model of multiple sclerosis. J Neurol Sci 150:103-113.
25. Jeffery ND, Blakemore WF (1995) Remyelination of mouse spinal cord axons demyelinated by local injection of lysolecithin. J Neurocytol 24:775-781.
26. Jung-Testas I, Hu ZY, Baulieu EE, Robel P (1989) Neurosteroids: biosynthesis of pregnenolone and progesterone in primary cultures of rat glial cells. Endocrinology 125:2083-2091.
27. Knobler RL, Saneto RP, Altman A, Johnson MM, de Vellis J (1988) Imerleukin-2 blocks oligodendrocyte progenitor proliferation. Ann NY Acad Sci 540:324-426.
28. Kumar S, Cole R, Chiappelli F, De Velus J (1989) Differential regulation oligodendrocyte markers by glucocorticoids: post transcriptional regulation of both proteolipid protein and myelin basic protein and transcriptional regulation of glycerol phosphate dehydrogenase. Proc Natl Acad Sci USA 86:6807-6811.
29. Lew W, Oppenheim JJ, Matsushima K (1988) Analysis of the suppression of IL-1 alpha and IL-1 beta production in human peripheral blood mononuclear adherent cells by a glucocorticoid hormone. J Immunol 140:1895-1902.
30. Ludwin SK (1979) An autoradiographic study of cellular proliferation in remyelination of the central nervous system. Am J Pathol 95:683-696.
31. Miller DJ, Rodriguez M (1995) A monoclonal antibody that promotes central nervous system remyelination in a model of multiple sclerosis is a natural autoantibody encoded by germline immunoglobulin genes. J Immunol 154:2640-2649.
32. Miller DJ, Sanborn KS, Katzmann JA, Rodriguez M (1994) Monoclonal autoantibodies promote central nervous system repair in an animal model of multiple sclerosis. J Neurosci 14:6230-6238.
33. Miller DJ, Njenga MK, Murray PD, Leibowitz J, Rodriguez M (1996) A monoclonal natural autoantibody that promotes remyelination suppresses central nervous system inflammation and increases virus expression after Theiler's virus-induced demyelination. Int Immunol 8:131-141.
34. Miller DJ, Bright JJ, Sriram S, Rodriguez M (1997) Successful treatment of established relapsing experimental autoimmune encephalomyelitis in mice with a monoclonal natural autoantibody. J Neuroimmunol 75:204-209.
35. Neuberger TJ, Kalimi O, Regelson W, Kalimi M, De Vries GH (1994) Glucocorticoids enhance the potency of Schwann cell mitogens. J Neurosci Res 38:300-313.
36. Prayoonwiwat N, Rodriguez M (1993) The potential for oligodendrocyte proliferation during demyelinating disease. J Neuropath Exp Neurol 52:55-63.
37. Prineas JW, Connell F (1979) Remyelination in multiple sclerosis. Ann Neurol 5:22-31.
38. Raine CS, Traugott U (1985) Remyelination in chronic relapsing experimental allergic encephalomyelitis and multiple sclerosis. In: The pathology of myelinated axon (Adachi M, Hirano A, Aronson SM eds), pp 229-275. New York: Igaku-Shoin.
39. Rodriguez M, Lennon VA (1990) Immunoglobulins promote remyelination in the central nervous system. Ann Neurol 27:12-17.
40. Rodriguez M, Lindsley MD (1992) Immunosuppression promotes CNS remyelination in chronic virus-induced demyelinating disease. Neurology 42:348-357.
41. Rodriguez M, Sheithauer B (1994) Ultrastructure of multiple sclerosis. Ultrastruct Pathol 18:3-13.
42. Rodriguez M, Lennon VA, Benveniste EN, Merrill JE (1987) Remyelination by oligodendrocytes stimulated by antiserum to spinal cord. J Neuropathol Exp Neurol 46:84-95.
43. Triarhou LC, Herndon RM (1986) The effect of dexamethasone on L-alphalysolphosphatidyl choline (lysolecithin)-induced demyelination. Arch Neurol 43:121-125.
44. Trotter J, Smith ME (1986) The role of phospholipases from inflammatory macrophages in demyelination. Neurochem Res 11:349-361.
45. Van Engelen BGM, Miller DJ, Pavelko KD, Hommes OR, Rodriguez M (1995) Promotion of remyelination by polyclonal immunoglobulin in Theiler's virus-induced demyelination and in multiple sclerosis. J Neurol Neurosurg Psychiatry 57:65-68.
46. Weltzien HU (1979) Cytolytic and membrane-perturbing properties of lysophosphatidylcholine. Biochim Biophys Acta 559:259-287.
47. Yajima K, Suzuki K (1979) Demyelination and remyelination in the rat central nervous system following ethidium bromide injection. Lab Invest 41:385-392.