Solution structure and intramolecular exchange of methyl-cytosine binding domain protein 4 (MBD4) on DNA suggests a mechanism to scan for mCpG/TpG mismatches

Nucleic Acids Research

Volumn 42, Issue 17, 2014, Pages 11218-11232

  Walavalkar, Ninad M ^a   Cramer, Jason M ^b   Buchwald, William A ^a   Scarsdale, J Neel ^c   Williams, David C ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DNA GLYCOSYLTRANSFERASE; DOUBLE STRANDED DNA; METHYL CYTOSINE BINDING DOMAIN PROTEIN 4; UNCLASSIFIED DRUG; DEOXYRIBONUCLEASE; DNA; MBD4 PROTEIN, HUMAN; SODIUM CHLORIDE;

AMINO TERMINAL SEQUENCE; ARTICLE; BASE MISPAIRING; BINDING AFFINITY; BINDING SITE; CATALYSIS; CONTROLLED STUDY; CPG ISLAND; DEAMINATION; DNA PURIFICATION; ENZYME ACTIVITY; GENE SILENCING; HUMAN; MISMATCH REPAIR; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN TARGETING; TUMOR SUPPRESSOR GENE; CHEMICAL STRUCTURE; CHEMISTRY; DNA METHYLATION; METABOLISM; PROTEIN TERTIARY STRUCTURE;

BASE PAIR MISMATCH; BINDING SITES; CPG ISLANDS; DNA; DNA METHYLATION; ENDODEOXYRIBONUCLEASES; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; SODIUM CHLORIDE;

EID: 84923327323     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku782     Document Type: Article

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