Active accumulation of very diluted biomolecules by nano-dispensing for easy detection below the femtomolar range

Nature Communications

Volumn 5, Issue , 2014, Pages

  Grilli, S ^a   Miccio, L ^a   Gennari, O ^a   Coppola, S ^a   Vespini, V ^a   Battista, L ^a   Orlando, P ^a,b   Ferraro, P ^a  

^a ISTITUTO NAZIONALE DI OTTICA   (Italy)

^b CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GLIADIN; NANOCRYSTAL; NANOPARTICLE; OLIGONUCLEOTIDE; TIN;

ACCUMULATION; CONCENTRATION (COMPOSITION); DETECTION METHOD; DROPLET; NANOTECHNOLOGY; NUCLEIC ACID; PROTEIN; SOLUTION;

ARTICLE; BINDING SITE; BIOACCUMULATION; BIOSENSOR; CHEMICAL INTERACTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DENSITY; ELECTRIC FIELD; ELECTRIC POTENTIAL; ENZYME LINKED IMMUNOSORBENT ASSAY; EVAPORATION; HUMAN; HYDROPHOBICITY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; METAL BINDING; MOLECULAR DYNAMICS; MOLECULAR WEIGHT; NANOFLUIDICS; NANOPIPETTE; NANOTECHNOLOGY; OSMOLARITY; PROTEIN ANALYSIS; PROTEIN ELECTROPHORESIS; SIGNAL NOISE RATIO; SURFACE CHARGE; THERMAL STIMULATION; REPRODUCIBILITY;

ENZYME-LINKED IMMUNOSORBENT ASSAY; GLIADIN; LIMIT OF DETECTION; NANOTECHNOLOGY; OLIGONUCLEOTIDES; REPRODUCIBILITY OF RESULTS;

EID: 84923313987     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6314     Document Type: Article

References (40)

1. Diamond, D. Principles of Chemical and Biological Sensors (ed. Diamond, D.) 1-18 (John Wiley & Sons, 1998).
2. Ng, A. H. C., Uddayasankar, U. & Wheeler, A. R. Immunoassays in microfluidic systems. Anal. Bioanal. Chem. 397, 991-1007 (2010).
3. Arrabito, G. & Pignataro, B. Solution processed micro- and nano-bioarrays for multiplexed biosensing. Anal. Chem. 84, 5450-5462 (2012).
4. Arrabito, G., Galati, C., Castellano, S. & Pignataro, B. Luminometric subnanoliter droplet-to-droplet array (LUMDA) and its application to drug screening by phase I metabolism enzymes. Lab. Chip 13, 68-72 (2013).
5. Cuendet, M., Mesecar, A. D., DeWitt, D. L. & Pezzuto, J. M. An ELISA method to measure inhibition of the COX enzymes. Nat. Protoc. 1, 1915-1921 (2006).
6. Arlett, J. L., Myers, E. B. & Roukes, M. L. Comparative advantages of mechanical biosensors. Nat. Nanotechnol. 6, 203-215 (2011).
7. Kurita, R., Yokota, Y., Sato, Y., Mizutani, F. & Niwa, O. On-Chip enzyme immunoassay of a cardiac marker using a microfluidic device combined with a portable surface plasmon resonance system. Anal. Chem. 78, 5525-5531 (2006).
8. Yao, X. et al. Sub-attomole oligonucleotide and p53 cDNA determinations via a high-resolution surface plasmon resonance combined with oligonucleotidecapped gold nanoparticle signal amplification. Anal. Biochem. 354, 220-228 (2006).
9. Anker, J. N. et al. Biosensing with plasmonic nanosensors. Nat. Mater. 7, 442-453 (2008).
10. de Angelis, F. et al. Hybrid plasmonic-photonic nanodevice for label-free detection of a few molecules. Nano Lett. 8, 2321-2327 (2008).
11. De Angelis, F. et al. Breaking the diffusion limit with super-hydrophobic delivery of molecules to plasmonic nanofocusing SERS structures. Nat. Photon. 5, 682-687 (2011).
12. Wu, G. et al. Bioassay of prostate-specific antigen (PSA) using microcantilevers. Nat. Biotechnol. 19, 856-860 (2001).
13. Armani, A. M., Kulkarni, R. P., Fraser, S. E., Flagan, R. C. & Vahala, K. J. Label-Free, single-molecule detection with optical microcavities. Science 317, 783-787 (2007).
14. Waggoner, P. S., Varshney, M. & Craighead, H. G. Detection of prostate specific antigen with nanomechanical resonators. Lab. Chip 9, 3095-3099 (2009).
15. Lu, Y., Peng, S., Luo, D. & Lal, A. Low-concentration mechanical biosensor based on a photonic crystal nanowire array. Nat. Commun. 2, 578-583 (2011).
16. Krivitsky, V. et al. Si nanowires forest-based on-chip biomolecular filtering, separation and preconcentration devices: nanowires do it all. Nano Lett. 12, 4748-4756 (2012).
17. Zheng, G., Patolsky, F., Cui, Y., Wang, W. U. & Lieber, C. M. Multiplexed electrical detection of cancer markers with nanowire sensor arrays. Nat. Biotechnol. 23, 1294-1301 (2005).
18. Escobedo, C., Brolo, A. G., Gordon, R. & Sinton, D. Optofluidic concentration: plasmonic nanostructure as concentrator and sensor. Nano Lett. 12, 1592-1596 (2012).
19. Wang, Y. & Han, J. Pre-binding dynamic range and sensitivity enhancement for immuno-sensors using nanofluidic preconcentrator. Lab. Chip 8, 392-394 (2008).
20. Lin, C.-C., Hsu, J.-L. & Lee, G.-B. Sample preconcentration in microfluidic devices. Microfluid. Nanofluid. 10, 481-511 (2010).
21. Kim, S. J., Song, Y.-A. & Han, J. Nanofluidic concentration devices for biomolecules utilizing ion concentration polarization: theory, fabrication, and applications. Chem. Soc. Rev. 39, 912-922 (2010).
22. Elghanian, R., Storhoff, J. J., Mucic, R. C., Letsinger, R. L. & Mirkin, C. A. Selective colorimetric detection of polynucleotides based on the distancedependent optical properties of gold nanoparticles. Science 277, 1078-1081 (1997).
23. Nam, J.-M., Thaxton, C. S. & Mirkin, C. A. Nanoparticle-based bio-bar codes for the ultrasensitive detection of proteins. Science 301, 1884-1886 (2003).
24. De, M., Ghosh, P. S. & Rotello, V. M. Applications of nanoparticles in biology. Adv. Mater. 20, 4225-4241 (2008).
25. Weizmann, Y., Patolsky, F. & Willner, I. Amplified detection of DNA and analysis of single-base mismatches by the catalyzed deposition of gold on Aunanoparticles. Analyst 126, 1502-1504 (2001).
26. Goluch, E. D. et al. A bio-barcode assay for on-chip attomolar-sensitivity protein detection. Lab Chip 6, 1293-1299 (2006).
27. Rica, R. D. e. & Stevens, M. M. Plasmonic ELISA for the detection of analytes at ultralow concentrations with the naked eye. Nat. Protoc. 8, 1759-1764 (2013).
28. Crystal, P. et al. Ultrasensitive on-chip immunoassays with a nanoparticleassembled photonic crystal. ACS Nano 6, 8570-8582 (2012).
29. Varriale, A. et al. Fluorescence correlation spectroscopy assay for gliadin in food. Anal. Chem. 79, 4687-4689 (2007).
30. Trantum, J. R., Baglia, M. L., Eagleton, Z. E., Mernaugh, R. L. & Haselton, F. R. Biosensor design based on Marangoni flow in an evaporating drop. Lab. Chip 14, 315-324 (2014).
31. Kumar, S., Wittenberg, N. J. & Oh, S. Nanopore-induced spontaneous concentration for optofluidic sensing and particle assembly. Anal. Chem. 85, 971-977 (2013).
32. Wang, P., Liang, O., Zhang, W., Schroeder, T. & Xie, Y.-H. Ultra-sensitive graphene-plasmonic hybrid platform for label-free detection. Adv. Mater. 25, 4918-4924 (2013).
33. Taylor, G. I. & McEwan, A. D. The stability of a horizontal fluid interface in a vertical electric field. J. Fluid Mech. 22, 1-15 (1965).
34. Ferraro, P., Coppola, S., Grilli, S., Paturzo, M. & Vespini, V. Dispensing nano-pico droplets and liquid patterning by pyroelectrodynamic shooting. Nat. Nanotechnol. 5, 429-435 (2010).
35. Coppola, S., Vespini, V., Grilli, S. & Ferraro, P. Self-assembling of multi-jets by pyro-electrohydrodynamic effect for high throughput liquid nanodrops transfer. Lab Chip 11, 3294-3298 (2011).
36. Shena, M. (ed. Biotechniques Books: Microarray Biochip Technology, 1st edn (Eaton Publishing Company, 2000).
37. Lee, J.-G. et al. Electrohydrodynamic (EHD) dispensing of nanoliter DNA droplets for microarrays. Biosens. Bioelectron. 21, 2240-2247 (2006).
38. Park, J.-U., Lee, J. H., Paik, U., Lu, Y. & Rogers, J. A. Nanoscale patterns of oligonucleotides formed by electrohydrodynamic jet printing with applications in biosensing and nanomaterials assembly. Nano Lett. 8, 4210-4216 (2008).
39. Bhandari, D. Rapid Wheat Varietal Identification using the Agilent 2100 Bioanalyzer and Automated Pattern-matching. Application Note: 5989-7735EN (Agilent Technologies, 2008).
40. Wieser, H., Modl, A., Seilmeier, W. & Belitz, H.-D. Extractability of glutenins with water/alcohol mixtures under reducing conditions. Z. Lbensm. Forsch. 185, 371-378 (1987).