Targeting TopBP1 at a convergent point of multiple oncogenic pathways for cancer therapy

Nature Communications

Volumn 5, Issue , 2014, Pages

  Chowdhury, Pinki ^a   Lin, Gregory E ^a,b   Liu, Kang ^a   Song, Yongcheng ^a   Lin, Fang Tsyr ^a   Lin, Weei Chin ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b Rice University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCEIN; ONCOPROTEIN; PROTEIN P53; TOPBP 1; UNCLASSIFIED DRUG; CARRIER PROTEIN; DNA BINDING PROTEIN; E2F1 PROTEIN, HUMAN; FLUORESCEIN DERIVATIVE; NUCLEAR PROTEIN; TOPBP1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR E2F1;

APOPTOSIS; CANCER; DISEASE CONTROL; GENE EXPRESSION; MOLECULAR ANALYSIS; MUTATION; NUMERICAL MODEL; PERMEABILITY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER THERAPY; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG TARGETING; FEMALE; GAIN OF FUNCTION MUTATION; HUMAN; HUMAN CELL; MOLECULAR DOCKING; MOUSE; NEOPLASM; NONHUMAN; OLIGOMERIZATION; PROTEIN BINDING; ANIMAL; BREAST NEOPLASMS; CANCER TRANSPLANTATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; NEOPLASMS; PATHOPHYSIOLOGY; PHYSIOLOGY; TUMOR CELL CULTURE; XENOGRAFT;

ANIMALS; APOPTOSIS; BREAST NEOPLASMS; CARRIER PROTEINS; DNA-BINDING PROTEINS; E2F1 TRANSCRIPTION FACTOR; FEMALE; FLUORESCEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HETEROGRAFTS; HUMANS; MICE; NEOPLASM TRANSPLANTATION; NEOPLASMS; NUCLEAR PROTEINS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84923295067     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6476     Document Type: Article

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