-
1
-
-
0030201099
-
Excessive urokinase-type plasminogen activator activity in the euglobulin fraction of patients with Alzheimer-type dementia
-
D.F. Alonso, E.F. Farias, A.L. Famulari, R.O. Dominguez, S. Kohan, and E.S. de Lustig Excessive urokinase-type plasminogen activator activity in the euglobulin fraction of patients with Alzheimer-type dementia J. Neurol Sci. 139 1996 83 88
-
(1996)
J. Neurol Sci.
, vol.139
, pp. 83-88
-
-
Alonso, D.F.1
Farias, E.F.2
Famulari, A.L.3
Dominguez, R.O.4
Kohan, S.5
De Lustig, E.S.6
-
2
-
-
84878278056
-
Tissue-type plasminogen activator binds to Abeta and AIAPP amyloid fibrils with multiple domains
-
D.X. Beringer, M.J. Fischer, J.D. Meeldijk, E.G. van Donselaar, N.J. de Mol, and L.M. Kroon-Batenburg Tissue-type plasminogen activator binds to Abeta and AIAPP amyloid fibrils with multiple domains Amyloid 20 2013 113 121
-
(2013)
Amyloid
, vol.20
, pp. 113-121
-
-
Beringer, D.X.1
Fischer, M.J.2
Meeldijk, J.D.3
Van Donselaar, E.G.4
De Mol, N.J.5
Kroon-Batenburg, L.M.6
-
3
-
-
34547131583
-
Ageing and amyloid-beta peptide deposition contribute to an impaired brain tissue plasminogen activator activity by different mechanisms
-
M. Cacquevel, S. Launay, H. Castel, K. Benchenane, S. Cheenne, L. Buee, L. Moons, A. Delacourte, P. Carmeliet, and D. Vivien Ageing and amyloid-beta peptide deposition contribute to an impaired brain tissue plasminogen activator activity by different mechanisms Neurobiol. Dis. 27 2007 164 173
-
(2007)
Neurobiol. Dis.
, vol.27
, pp. 164-173
-
-
Cacquevel, M.1
Launay, S.2
Castel, H.3
Benchenane, K.4
Cheenne, S.5
Buee, L.6
Moons, L.7
Delacourte, A.8
Carmeliet, P.9
Vivien, D.10
-
4
-
-
84862805757
-
Neuroprotection by urokinase plasminogen activator in the hippocampus
-
E. Cho, K.J. Lee, J.W. Seo, C.J. Byun, S.J. Chung, D.C. Suh, P. Carmeliet, J.Y. Koh, J.S. Kim, and J.Y. Lee Neuroprotection by urokinase plasminogen activator in the hippocampus Neurobiol. Dis. 46 2012 215 224
-
(2012)
Neurobiol. Dis.
, vol.46
, pp. 215-224
-
-
Cho, E.1
Lee, K.J.2
Seo, J.W.3
Byun, C.J.4
Chung, S.J.5
Suh, D.C.6
Carmeliet, P.7
Koh, J.Y.8
Kim, J.S.9
Lee, J.Y.10
-
5
-
-
0037928427
-
Amyloid beta-protein stimulates the expression of urokinase-type plasminogen activator (uPA) and its receptor (uPAR) in human cerebrovascular smooth muscle cells
-
J. Davis, M.R. Wagner, W. Zhang, F. Xu, and W.E. Van Nostrand Amyloid beta-protein stimulates the expression of urokinase-type plasminogen activator (uPA) and its receptor (uPAR) in human cerebrovascular smooth muscle cells J. Biol. Chem. 278 2003 19054 19061
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 19054-19061
-
-
Davis, J.1
Wagner, M.R.2
Zhang, W.3
Xu, F.4
Van Nostrand, W.E.5
-
6
-
-
13544273507
-
Elevated amyloid beta protein (Abeta42) and late onset Alzheimers disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene
-
N. Ertekin-Taner, J. Ronald, L. Feuk, J. Prince, M. Tucker, L. Younkin, M. Hella, S. Jain, A. Hackett, L. Scanlin, J. Kelly, M. Kihiko-Ehman, M. Neltner, L. Hersh, M. Kindy, W. Markesbery, M. Hutton, M. de Andrade, R.C. Petersen, N. Graff-Radford, S. Estus, A.J. Brookes, and S.G. Younkin Elevated amyloid beta protein (Abeta42) and late onset Alzheimers disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene Hum. Mol. Genet. 14 2005 447 460
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 447-460
-
-
Ertekin-Taner, N.1
Ronald, J.2
Feuk, L.3
Prince, J.4
Tucker, M.5
Younkin, L.6
Hella, M.7
Jain, S.8
Hackett, A.9
Scanlin, L.10
Kelly, J.11
Kihiko-Ehman, M.12
Neltner, M.13
Hersh, L.14
Kindy, M.15
Markesbery, W.16
Hutton, M.17
De Andrade, M.18
Petersen, R.C.19
Graff-Radford, N.20
Estus, S.21
Brookes, A.J.22
Younkin, S.G.23
more..
-
7
-
-
0035903270
-
Plasmin cleaves Abeta42 in vitro and prevents its aggregation into beta-pleated sheet structures
-
C. Exley, and O.V. Korchazhkina Plasmin cleaves Abeta42 in vitro and prevents its aggregation into beta-pleated sheet structures Neuroreport 12 2001 2967 2970
-
(2001)
Neuroreport
, vol.12
, pp. 2967-2970
-
-
Exley, C.1
Korchazhkina, O.V.2
-
8
-
-
0141568946
-
Association of late-onset Alzheimer disease with a genotype of PLAU, the gene encoding urokinase-type plasminogen activator on chromosome 10q22.2
-
U. Finckh, K. van Hadeln, T. Muller-Thomsen, A. Alberici, G. Binetti, C. Hock, R.M. Nitsch, G. Stoppe, J. Reiss, and A. Gal Association of late-onset Alzheimer disease with a genotype of PLAU, the gene encoding urokinase-type plasminogen activator on chromosome 10q22.2 Neurogenetics 4 2003 213 217
-
(2003)
Neurogenetics
, vol.4
, pp. 213-217
-
-
Finckh, U.1
Van Hadeln, K.2
Muller-Thomsen, T.3
Alberici, A.4
Binetti, G.5
Hock, C.6
Nitsch, R.M.7
Stoppe, G.8
Reiss, J.9
Gal, A.10
-
9
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
K. Hsiao, P. Chapman, S. Nilsen, C. Eckman, Y. Harigaya, S. Younkin, F. Yang, and G. Cole Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice Science 274 1996 99 102
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
10
-
-
0028928084
-
In vitro stimulation of tissue-type plasminogen activator by Alzheimer amyloid beta-peptide analogues
-
I.B. Kingston, M.J. Castro, and S. Anderson In vitro stimulation of tissue-type plasminogen activator by Alzheimer amyloid beta-peptide analogues Nat. Med 1 1995 138 142
-
(1995)
Nat. Med
, vol.1
, pp. 138-142
-
-
Kingston, I.B.1
Castro, M.J.2
Anderson, S.3
-
11
-
-
0037195269
-
Tissue-type plasminogen activator is a multiligand cross-beta structure receptor
-
O. Kranenburg, B. Bouma, L.M. Kroon-Batenburg, A. Reijerkerk, Y.P. Wu, E.E. Voest, and M.F. Gebbink Tissue-type plasminogen activator is a multiligand cross-beta structure receptor Curr. Biol. 12 2002 1833 1839
-
(2002)
Curr. Biol.
, vol.12
, pp. 1833-1839
-
-
Kranenburg, O.1
Bouma, B.2
Kroon-Batenburg, L.M.3
Reijerkerk, A.4
Wu, Y.P.5
Voest, E.E.6
Gebbink, M.F.7
-
12
-
-
0039589444
-
Plasminogen activator secretion by granule neurons in cultures of developing cerebellum
-
A. Krystosek, and N.W. Seeds Plasminogen activator secretion by granule neurons in cultures of developing cerebellum P. Natl. Acad. Sci. USA. 78 1981 7810 7814
-
(1981)
P. Natl. Acad. Sci. USA.
, vol.78
, pp. 7810-7814
-
-
Krystosek, A.1
Seeds, N.W.2
-
13
-
-
0034573026
-
Brain plasmin enhances APP alpha-cleavage and Abeta degradation and is reduced in Alzheimers disease brains
-
M.D. Ledesma, J.S. Da Silva, K. Crassaerts, A. Delacourte, B. De Strooper, and C.G. Dotti Brain plasmin enhances APP alpha-cleavage and Abeta degradation and is reduced in Alzheimers disease brains EMBO Rep. 1 2000 530 535
-
(2000)
EMBO Rep.
, vol.1
, pp. 530-535
-
-
Ledesma, M.D.1
Da Silva, J.S.2
Crassaerts, K.3
Delacourte, A.4
De Strooper, B.5
Dotti, C.G.6
-
14
-
-
34547451637
-
Upregulation of tPA/plasminogen proteolytic system in the periphery of amyloid deposits in the Tg2576 mouse model of Alzheimers disease
-
J.Y. Lee, H.S. Kweon, E. Cho, H.R. Byun, D.H. Kim, Y.H. Kim, P.L. Han, and J.Y. Koh Upregulation of tPA/plasminogen proteolytic system in the periphery of amyloid deposits in the Tg2576 mouse model of Alzheimers disease Neurosci. Lett. 423 2007 82 87
-
(2007)
Neurosci. Lett.
, vol.423
, pp. 82-87
-
-
Lee, J.Y.1
Kweon, H.S.2
Cho, E.3
Byun, H.R.4
Kim, D.H.5
Kim, Y.H.6
Han, P.L.7
Koh, J.Y.8
-
15
-
-
84863233084
-
Alteration of the cerebral zinc pool in a mouse model of Alzheimer disease
-
J.Y. Lee, E. Cho, J.W. Seo, J.J. Hwang, and J.Y. Koh Alteration of the cerebral zinc pool in a mouse model of Alzheimer disease J. Neuropath. Exp. Neur. 71 2012 211 222
-
(2012)
J. Neuropath. Exp. Neur.
, vol.71
, pp. 211-222
-
-
Lee, J.Y.1
Cho, E.2
Seo, J.W.3
Hwang, J.J.4
Koh, J.Y.5
-
16
-
-
79955954909
-
Knockout of plasminogen activator inhibitor 1 gene reduces amyloid beta peptide burden in a mouse model of Alzheimers disease
-
R.M. Liu, T.K.A. van Groen, D. Cao, I. Kadisha, C. Ballinger, L. Wang, S.L. Carroll, and L. Li Knockout of plasminogen activator inhibitor 1 gene reduces amyloid beta peptide burden in a mouse model of Alzheimers disease Neurobiol. Aging 32 2011 1079 1089
-
(2011)
Neurobiol. Aging
, vol.32
, pp. 1079-1089
-
-
Liu, R.M.1
Van Groen, T.K.A.2
Cao, D.3
Kadisha, I.4
Ballinger, C.5
Wang, L.6
Carroll, S.L.7
Li, L.8
-
17
-
-
54249150387
-
Identification of fibronectin type i domains as amyloid-binding modules on tissue-type plasminogen activator and three homologs
-
C. Maas, B. Schiks, R.D. Strangi, T.M. Hackeng, B.N. Bouma, M.F. Gebbink, and B. Bouma Identification of fibronectin type I domains as amyloid-binding modules on tissue-type plasminogen activator and three homologs Amyloid 15 2008 166 180
-
(2008)
Amyloid
, vol.15
, pp. 166-180
-
-
Maas, C.1
Schiks, B.2
Strangi, R.D.3
Hackeng, T.M.4
Bouma, B.N.5
Gebbink, M.F.6
Bouma, B.7
-
18
-
-
0141641077
-
The tissue plasminogen activator-plasminogen proteolytic cascade accelerates amyloid-beta (Abeta) degradation and inhibits Abeta-induced neurodegeneration
-
J.P. Melchor, R. Pawlak, and S. Strickland The tissue plasminogen activator-plasminogen proteolytic cascade accelerates amyloid-beta (Abeta) degradation and inhibits Abeta-induced neurodegeneration J. Neurosci. 23 2003 8867 8871
-
(2003)
J. Neurosci.
, vol.23
, pp. 8867-8871
-
-
Melchor, J.P.1
Pawlak, R.2
Strickland, S.3
-
19
-
-
0027184611
-
Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimers disease
-
D.L. Miller, I.A. Papayannopoulos, J. Styles, S.A. Bobin, Y.Y. Lin, K. Biemann, and K. Iqbal Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimers disease Arch. Biochem. Biophys. 301 1993 41 52
-
(1993)
Arch. Biochem. Biophys.
, vol.301
, pp. 41-52
-
-
Miller, D.L.1
Papayannopoulos, I.A.2
Styles, J.3
Bobin, S.A.4
Lin, Y.Y.5
Biemann, K.6
Iqbal, K.7
-
20
-
-
42149164312
-
Processing of amyloid precursor protein and amyloid peptide neurotoxicity
-
P. Nathalie, and O. Jean-Noel Processing of amyloid precursor protein and amyloid peptide neurotoxicity Curr. Alz. Res. 5 2008 92 99
-
(2008)
Curr. Alz. Res.
, vol.5
, pp. 92-99
-
-
Nathalie, P.1
Jean-Noel, O.2
-
21
-
-
84889605586
-
Tissue plasminogen activator arrests Alzheimers disease pathogenesis
-
S.B. Oh, C.J. Byun, J.H. Yun, D.G. Jo, P. Carmeliet, J.Y. Koh, and J.Y. Lee Tissue plasminogen activator arrests Alzheimers disease pathogenesis Neurobiol. Aging 35 2014 511 519
-
(2014)
Neurobiol. Aging
, vol.35
, pp. 511-519
-
-
Oh, S.B.1
Byun, C.J.2
Yun, J.H.3
Jo, D.G.4
Carmeliet, P.5
Koh, J.Y.6
Lee, J.Y.7
-
22
-
-
0027535364
-
Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation
-
Z. Qian, M.E. Gilbert, M.A. Colicos, E.R. Kandel, and D. Kuhl Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation Nature 361 1993 453 457
-
(1993)
Nature
, vol.361
, pp. 453-457
-
-
Qian, Z.1
Gilbert, M.E.2
Colicos, M.A.3
Kandel, E.R.4
Kuhl, D.5
-
23
-
-
33747884644
-
A functional polymorphism within plasminogen activator urokinase (PLAU) is associated with Alzheimers disease
-
M. Riemenschneider, L. Konta, P. Friedrich, S. Schwarz, K. Taddei, F. Neff, A. Padovani, H. Kolsch, S.M. Laws, N. Klopp, H. Bickeboller, S. Wagenpfeil, J.C. Mueller, A. Rosenberger, J. Diehl-Schmid, S. Archetti, N. Lautenschlager, B. Borroni, U. Muller, T. Illig, R. Heun, R. Egensperger, J. Schlegel, H. Forstl, R.N. Martins, and A. Kurz A functional polymorphism within plasminogen activator urokinase (PLAU) is associated with Alzheimers disease Hum. Mol. Genet. 15 2006 2446 2456
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 2446-2456
-
-
Riemenschneider, M.1
Konta, L.2
Friedrich, P.3
Schwarz, S.4
Taddei, K.5
Neff, F.6
Padovani, A.7
Kolsch, H.8
Laws, S.M.9
Klopp, N.10
Bickeboller, H.11
Wagenpfeil, S.12
Mueller, J.C.13
Rosenberger, A.14
Diehl-Schmid, J.15
Archetti, S.16
Lautenschlager, N.17
Borroni, B.18
Muller, U.19
Illig, T.20
Heun, R.21
Egensperger, R.22
Schlegel, J.23
Forstl, H.24
Martins, R.N.25
Kurz, A.26
more..
-
24
-
-
67749147230
-
Age and albumin D site-binding protein control tissue plasminogen activator levels: Neurotoxic impact
-
B.D. Roussel, R. Macrez, A. Jullienne, V Agin, E. Maubert, L. Dauphinot, M.C. Potier, L. Plawinski, H. Castel, Y. Hommet, J. Munuera, J. Montaner, M. Yepes, C. Ali, and D. Vivien Age and albumin D site-binding protein control tissue plasminogen activator levels: neurotoxic impact Brain 132 2009 2219 2230
-
(2009)
Brain
, vol.132
, pp. 2219-2230
-
-
Roussel, B.D.1
Macrez, R.2
Jullienne, A.3
Agin, V.4
Maubert, E.5
Dauphinot, L.6
Potier, M.C.7
Plawinski, L.8
Castel, H.9
Hommet, Y.10
Munuera, J.11
Montaner, J.12
Yepes, M.13
Ali, C.14
Vivien, D.15
-
25
-
-
0038334811
-
Cell type-specific roles for tissue plasminogen activator released by neurons or microglia after excitotoxic injury
-
C.J. Siao, S.R. Fernandez, and S.E. Tsirka Cell type-specific roles for tissue plasminogen activator released by neurons or microglia after excitotoxic injury J. Neurosci. 23 2003 3234 3242
-
(2003)
J. Neurosci.
, vol.23
, pp. 3234-3242
-
-
Siao, C.J.1
Fernandez, S.R.2
Tsirka, S.E.3
-
26
-
-
4444379260
-
Tissue plasminogen activator and neuroserpin are widely expressed in the human central nervous system
-
T. Teesalu, A. Kulla, A. Simisker, V. Siren, D.A. Lawrence, T. Asser, and A. Vaheri Tissue plasminogen activator and neuroserpin are widely expressed in the human central nervous system Thromb. Haemostasis 92 2004 358 368
-
(2004)
Thromb. Haemostasis
, vol.92
, pp. 358-368
-
-
Teesalu, T.1
Kulla, A.2
Simisker, A.3
Siren, V.4
Lawrence, D.A.5
Asser, T.6
Vaheri, A.7
-
27
-
-
18544410708
-
The plasmin system is induced by and degrades amyloid-beta aggregates
-
H.M. Tucker, M. Kihiko, J.N. Caldwell, S. Wright, T. Kawarabayashi, D. Price, D. Walker, S. Scheff, J.P. McGillis, R.E. Rydel, and S. Estus The plasmin system is induced by and degrades amyloid-beta aggregates J. Neurosci. 20 2000 3937 3946
-
(2000)
J. Neurosci.
, vol.20
, pp. 3937-3946
-
-
Tucker, H.M.1
Kihiko, M.2
Caldwell, J.N.3
Wright, S.4
Kawarabayashi, T.5
Price, D.6
Walker, D.7
Scheff, S.8
McGillis, J.P.9
Rydel, R.E.10
Estus, S.11
-
28
-
-
0037107974
-
Urokinase-type plasminogen activator inhibits amyloid-beta neurotoxicity and fibrillogenesis via plasminogen
-
H.M. Tucker, M. Kihiko-Ehmann, and S. Estus Urokinase-type plasminogen activator inhibits amyloid-beta neurotoxicity and fibrillogenesis via plasminogen J. Neurosci. Res. 70 2002 249 255
-
(2002)
J. Neurosci. Res.
, vol.70
, pp. 249-255
-
-
Tucker, H.M.1
Kihiko-Ehmann, M.2
Estus, S.3
-
29
-
-
0033621048
-
Plasmin cleavage of the amyloid beta-protein: Alteration of secondary structure and stimulation of tissue plasminogen activator activity
-
W.E. Van Nostrand, and M. Porter Plasmin cleavage of the amyloid beta-protein: alteration of secondary structure and stimulation of tissue plasminogen activator activity Biochemistry 38 1999 11570 11576
-
(1999)
Biochemistry
, vol.38
, pp. 11570-11576
-
-
Van Nostrand, W.E.1
Porter, M.2
-
30
-
-
0031079734
-
Amyloid beta peptides stimulate tissue-type plasminogen activator but not recombinant prourokinase
-
S. Wnendt, I. Wetzels, and W.A. Gunzler Amyloid beta peptides stimulate tissue-type plasminogen activator but not recombinant prourokinase Thromb. Res. 85 1997 217 224
-
(1997)
Thromb. Res.
, vol.85
, pp. 217-224
-
-
Wnendt, S.1
Wetzels, I.2
Gunzler, W.A.3
|