Alginate core-shell beads for simplified three-dimensional tumor spheroid culture and drug screening

Biomedical Microdevices

Volumn 17, Issue 2, 2015, Pages

  Yu, Linfen ^a   Ni, Cynthia ^a   Grist, Samantha M ^a   Bayly, Carmen ^a   Cheung, Karen C ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

3 D cell culture; Cell laden hydrogel beads; Drug screening; Microfluidics

Indexed keywords

AGGREGATES; ALGINATE; BOTTLES; CELL CULTURE; CELL PROLIFERATION; CELLS; DIAGNOSIS; HYDROGELS; MICROFLUIDICS; MONOLAYERS; TUMORS;

3-D CELL CULTURE; CELL-BASED DRUG SCREENING; DRUG SCREENING; HYDROGEL BEADS; MCF-7 BREAST CANCER CELLS; MULTICELLULAR AGGREGATES; THREE-DIMENSIONAL CULTURE; THREEDIMENSIONAL (3-D);

SHELLS (STRUCTURES);

ALGINIC ACID; DOCETAXEL; TAMOXIFEN; GLUCURONIC ACID; HEXURONIC ACID; HYDROGEL; MICROSPHERE; TAXOID;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG SCREENING; ENCAPSULATION; HUMAN; HUMAN CELL; HYDROGEL; MCF 7 CELL LINE; MONOLAYER CULTURE; PRIORITY JOURNAL; TUMOR SPHEROID; CELL CULTURE TECHNIQUE; CHEMISTRY; DEVICES; DRUG EFFECTS; EQUIPMENT DESIGN; LAB ON A CHIP; PROCEDURES;

ALGINATES; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; EQUIPMENT DESIGN; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; HYDROGELS; LAB-ON-A-CHIP DEVICES; MCF-7 CELLS; MICROSPHERES; TAMOXIFEN; TAXOIDS;

EID: 84923197275     PISSN: 13872176     EISSN: 15728781     Source Type: Journal    
DOI: 10.1007/s10544-014-9918-5     Document Type: Article

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