Compressive and shear properties of alginate gel: Effects of sodium ions and alginate concentration

Journal of Biomedical Materials Research

Volumn 47, Issue 1, 1999, Pages 46-53

  LeRoux, Michelle A ^a   Guilak, Farshid ^a,b   Setton, Lori A ^a  

^a Duke University   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

3 dimensional matrix; Cell culture; Hydrogel; Mechanical properties; Tissue engineering

Indexed keywords

BIOPOLYMERS; CALCIUM COMPOUNDS; COMPOSITION EFFECTS; COMPRESSION TESTING; ELASTIC MODULI; HYDROGELS; PHYSIOLOGY; SODIUM CHLORIDE; STIFFNESS; STRESS ANALYSIS; STRESS RELAXATION; TISSUE CULTURE;

ALGINATE; SHEAR TESTS;

BIOMATERIALS;

ALGINIC ACID; CALCIUM ION; SODIUM CHLORIDE; SODIUM ION;

ARTICLE; CHEMICAL ANALYSIS; COMPRESSIVE STRENGTH; CONCENTRATION (PARAMETERS); CROSS LINKING; MECHANICS; SHEAR STRESS; STRESS STRAIN RELATIONSHIP; VISCOELASTICITY;

ALGINATES; BIOCOMPATIBLE MATERIALS; BIOMECHANICS; CALCIUM; CROSS-LINKING REAGENTS; ELASTICITY; GELS; ISOTONIC SOLUTIONS; MATERIALS TESTING; SODIUM; SODIUM CHLORIDE; VISCOSITY;

EID: 0032788329     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4636(199910)47:1<46::AID-JBM6>3.0.CO;2-N     Document Type: Article

References (33)

1. Grant GT, Morris ER, Rees DA, Smith PJC, Thom D. Biological interactions between polysaccharides and divalent cations: the egg-box model. FEES Lett 1973;32:195-198.
2. Guo J, Jourdian GW, MacCallum DK. Culture and growth characteristics of chondrocytes encapsulated in alginate beads. Connect Tissue Res 1989;19:277-297.
3. Smidsrød, O, Skjak-Bræk G. Alginate as immobilization matrix for cells. Trends Biotechnol 1990;8:71-78.
4. Clayton HA, James RF, Long NJ. Islet microencapsulation: a review. Acta Diabetol 1993;30:181-189.
5. Colton CK. Implantable biohybrid artificial organs. Cell Transplant 1995;4:415-436.
6. Duff RG. Microencapsulation technology: a novel method for monoclonal antibody production. Trends Biotechnol 1985;3: 167-170.
7. Paige KT, Cima LG, Yaremchuk MJ, Schloo BL, Vacanti JP, Vacanti CA. De novo cartilage generation using calcium alginate-chondrocyte constructs. Plast Reconstruct Surg 1996;97: 168-180.
8. Buschmann MD, Gluzband YA, Grodzinsky AJ, Hunziker EB. Mechanical compression modulates matrix biosynthesis in chondrocyte/agarose culture. J Cell Sci 1995;108:1497-1508.
9. Matsumoto T, Mashiko K. Viscoelastic properties of alginate aqueous solutions in the presence of salts. Biopolymers 1990; 29:1707-1713.
10. Smidsrød O, Haug A. The effect of divalent metals on the properties of alginate solutions. I. Calcium ions. Acta Chem Scand 1965;19:329-340.
11. Zheng H. Interaction mechanism in sol-gel transition of alginate solutions by addition of divalent cations. Carbohydr Res 1997;302:97-101.
12. Nussinovitch A, Peleg M. Strength-time relationships of agar and alginate gels. J Texture Studies 1990;21:51-60.
13. Thu B, Bruheim P, Espevik T, Smidsrød O, Soon-Shiong P, Skjak-Bræk G. Alginate polycation microcapsules. Biomaterials 1996;17:1069-1079.
14. Velings NM, Mestdagh MM. Physico-chemical properties of alginate gel beads. Polym Gels Networks 1995;3:311-329.
15. Haug A, Smidsrød O. The effect of divalent metals on the properties of alginate solutions. II. Comparison of different metal ions. Acta Chem Scand 1965;19:341-351.
16. Smidsrød O. Molecular basis for some physical properties of alginates in the gel state. Faraday Discuss Chem Soc 1974;57: 263-274.
17. Smidsrød O, Haug A. Properties of poly(1,4-hexuronates) in the gel state. II. Comparison of gels of different chemical composition. Acta Chem Scand 1972;26:79-88.
18. Yamagiwa K, Kozawa T, Ohkawa A. Effects of alginate composition and gelling conditions on diffusional and mechanical properties of calcium-alginate gel beads. J Chem Eng Jpn 1995; 28:462-267.
19. Martinsen A, Skjak-Bræk G, Smidsrød O. Alginate as immobilization material: I. Correlation between chemical and physical properties of alginate bel beads. Biotechnol Bioeng 1989;33:79-89.
20. Mitchell JR, Blanshard JM. Rheological properties of alginate gels. J Texture Studies 1976;7:219-234.
21. Smidsrød O, Huag A, Lian B. Properties of poly(1,4-hexuronates) in the gel state. I. Evaluation of a method for the determination of stiffness. Acta Chem Scand 1972;26:71-78.
22. Nussinovitch A, Peleg M, Normand MD. A modified Maxwell and a nonexponential model for characterization of the stress relaxation of agar and alginate gels. J Food Sci 1989;54:1013-1016.
23. Mitchell JR, Blanshard J. Viscoelastic behaviour of alginate gels. Rheol Acta 1974;13:180-184.
24. Segeren AJM, Boskamp JV, van den Tempel M. Rheological and swelling properties of alginate gels. Faraday Discuss Chem Soc 1974;57:255-274.
25. Freshney RI. The culture environment: substrate, gas phase, medium, and temperature. In: Culture of animal cells. New York: Alan R. Liss, Inc.; 1987. p 82.
26. Fung YC. Bioviscoelastic solids. In: Biomechanics: mechanical properties of living tissues. New York: Springer-Verlag; 1993. p 283-287.
27. Guilak F, Mow VC. Determination of the mechanical response of the chondrocyte in situ using finite element modeling and confocal microscopy. Adv Bioeng 1992;BED-22:21-23.
28. Vacanti JP, Vacanti C. The challenge of tissue engineering. In: Lanza RP, Langer R, Chick WL, editors. Principles of tissue engineering. Austin, TX: R. G. Langes Co.; 1997. p 1-5.
29. Maruyama K, Kaibara M, Fukada E. Rheology of F-actin. Biochim Biophys Acta 1974;371:20-29.
30. Zhu W, Iatridis JC, Hlibczuk V, Ratcliffe A, Mow VC. Determination of collagen-proteoglycan interactions in vitro. J Biomech 1996;29:773-783.
31. Zhu W, Mow VC, Rosenberg LC, Tang LH. Determination of kinetic changes of aggrecan-hyaluronan interactions in solution from its rheological properties. J Biomech 1994;27:571-579.
32. Roberts WW, Kramer O, Risser RW, Nestler FHM, Ferry JD. Rheology of fibrin clots. I. Dynamic viscoelastic properties and fluid permeation. Biophys Chem 1974;1:152-160.
33. Clark AH, Richardson RK, Ross-Murphy SB, Stubbs JM. Structural and mechanical properties of agar/gelatin co-gels. Small deformation studies. Macromolecules 1983;16:1367-1374.