Gonadal maldevelopment as risk factor for germ cell cancer: Towards a clinical decision model

European Urology

Volumn 67, Issue 4, 2015, Pages 692-701

  Van Der Zwan, Yvonne G ^a   Biermann, Katharina ^a   Wolffenbuttel, Katja P ^b   Cools, Martine ^c   Looijenga, Leendert H J ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^c GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Clinical decision guideline; DSDs; Epigenetics; GCC; Microenvironment

Indexed keywords

OCTAMER TRANSCRIPTION FACTOR 4; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR; TESTIS DETERMINING FACTOR; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX17; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTION FACTOR SOX9; OCTAMER TRANSCRIPTION FACTOR; TUMOR MARKER;

CANCER DIAGNOSIS; CANCER RISK; CARCINOMA IN SITU; CLINICAL DECISION MAKING; DIAGNOSTIC ERROR; DISEASE MODEL; DISORDER OF SEX DEVELOPMENT; EMBRYO DEVELOPMENT; ENVIRONMENTAL FACTOR; GERM CELL TUMOR; GONAD DEVELOPMENT; GONAD FUNCTION; GONADOBLASTOMA; HUMAN; MALIGNANT TRANSFORMATION; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; RISK ASSESSMENT; SEX DETERMINATION; SEX DIFFERENTIATION; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR MICROENVIRONMENT; BLOOD; COMPLICATION; CONGENITAL MALFORMATION; EARLY DIAGNOSIS; FEMALE; GONAD; MALE; NEOPLASMS, GERM CELL AND EMBRYONAL; PROCEDURES; RISK FACTOR;

BIOMARKERS, TUMOR; DISORDERS OF SEX DEVELOPMENT; EARLY DETECTION OF CANCER; FEMALE; GONADS; HUMANS; MALE; NEOPLASMS, GERM CELL AND EMBRYONAL; OCTAMER TRANSCRIPTION FACTORS; RISK FACTORS; SEX-DETERMINING REGION Y PROTEIN;

EID: 84923102603     PISSN: 03022838     EISSN: 18737560     Source Type: Journal    
DOI: 10.1016/j.eururo.2014.07.011     Document Type: Review

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