Ovarian gonadoblastoma with mixed germ cell tumor in a woman with 46,XX karyotype and successful pregnancies

Pathology International

Volumn 50, Issue 4, 2000, Pages 332-335

  Zhao, Shumei ^a   Kato, Noriko ^a   Endoh, Yasushi ^a   Jin, Zhe ^a   Ajioka, Youichi ^b   Motoyama, Teiichi ^a  

^a YAMAGATA UNIVERSITY   (Japan)

^b NIIGATA UNIVERSITY   (Japan)

Author keywords

Fertile woman; Gonadoblastoma; Mixed germ cell tumor

Indexed keywords

ALPHA FETOPROTEIN; CHORIONIC GONADOTROPIN; CISPLATIN; CONJUGATED ESTROGEN; DACTINOMYCIN; ETOPOSIDE; MEDROXYPROGESTERONE ACETATE; METHOTREXATE;

ADULT; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CASE REPORT; CHORIOCARCINOMA; CONTROLLED STUDY; DYSGERMINOMA; EMBRYONAL CARCINOMA; FEMALE; FEMALE FERTILITY; GERM CELL TUMOR; GONADOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; KARYOTYPE 46,XX; LAPAROTOMY; LYMPHADENECTOMY; MIXED TUMOR; OVARY TUMOR; PREGNANCY; PRIORITY JOURNAL; SALPINGOOOPHORECTOMY; TERATOMA; YOLK SAC TUMOR;

ADULT; FEMALE; GERMINOMA; GONADOBLASTOMA; HUMANS; KARYOTYPING; OVARIAN NEOPLASMS; PREGNANCY;

EID: 0033921841     PISSN: 13205463     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1827.2000.01041.x     Document Type: Article

References (15)

1. 1 Scully RE. Gonadoblastoma. A review of 74 cases. Cancer 1970; 25: 1340-1356.
2. 2 Schellhas HF. Malignant potential of the dysgenetic gonad. Part 1. Obstet. Gynecol. 1974; 44: 298-309.
3. 3 Hart WR, Burkons DM. Germ cell neoplasms arising in gonadoblastomas. Cancer 1979; 43: 669-678.
4. 4 De Bacalao EB, Dominguez I. Unilateral gonadoblastoma in a pregnant woman. Am. J. Obstet. Gynecol. 1969; 105: 1279-1281.
5. 5 Pratt-Thomas HR, Cooper JM. Gonadoblastoma with tubal pregnancy. Am. J. Clin. Pathol. 1976; 65: 121-125.
6. 6 Chellam VG, Mathew A, Varghese S. Unilateral gonadoblastoma with dysgerminoma in a normal fertile woman: Review and a report of a case. Ind. J. Cancer 1981; 18: 163-166.
7. 7 Nakashima N, Nagasaka T, Fukata S et al. Ovarian gonadoblastoma with dysgerminoma in a woman with two normal children. Hum. Pathol. 1989; 20: 814-816.
8. 8 Talerman A, Verp MS, Senekjian E, Gilewski T, Vogelzang N. True hermaphrodite with bilateral ovotestes, bilateral gonadoblastomas and dysgerminomas, 46,XX/46,XY karyotype, and a successful pregnancy. Cancer 1990; 66: 2668-2672.
9. 9 Erhan Y, Toprak AS, Özdemir N, Tiras B. Gonadoblastoma and fertility. J. Clin. Pathol. 1992; 45: 828-829.
10. 10 Verp MS, Simpson JL. Abnormal sexual differentiation and neoplasia. Cancer Genet. Cytogenet. 1987; 25: 191-218.
11. 11 Ulbright TM, Roth LM, Brodhecker CA. Yolk sac differentiation in germ cell tumors. A morphologic study of 50 cases with emphasis on hepatic, enteric, and parietal yolk sac features. Am. J. Surg. Pathol. 1986; 10: 151-164.
12. 12 Kawai M, Kano T, Furuhashi Y et al. Prognostic factors in yolk sac tumors of the ovary. A clinicopathologic analysis of 29 cases. Cancer 1991; 67: 184-192.
13. 13 Talerman A. Gonadoblastoma. In: Kurman RJ, eds. Blaustein's Pathology of the Female Genital Tract. Springer-Verlag, Berlin, 1994; 896-901.
14. 14 Talerman A. Gonadoblastoma associated with embryonal carcinoma. Obstet. Gynecol. 1974; 43: 138-142.
15. 15 Baranzlli MC, Patte C, Bouffet E et al. Malignant non-seminomatous germinal tumors of the ovary. Experience of the French Society of Pediatric Oncology. Contracept. Fertil. Sex. 1999; 27: 133-139.