Copper isotope effect in serum of cancer patients. A pilot study

Metallomics

Volumn 7, Issue 2, 2015, Pages 299-308

  Télouk, Philippe ^a   Puisieux, Alain ^b   Fujii, Toshiyuki ^c   Balter, Vincent ^a   Bondanese, Victor P ^a   Morel, Anne Pierre ^b   Clapisson, Gilles ^b   Lamboux, Aline ^a   Albarede, Francis ^a,d  

^a UNIVERSITÉ DE LYON   (France)

^b UNIVERSITÉ LYON 1   (France)

^c KYOTO UNIVERSITY   (Japan)

^d NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMARKERS; BLOOD; CHELATION; COPPER; DIAGNOSIS; INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY; ISOTOPES;

CANCER PATIENTS; COLORECTAL CANCER; DIAGNOSTIC TOOLS; ISOTOPE COMPOSITIONS; MOLECULAR BIOMARKER; MULTIPLE COLLECTOR INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY; NATURAL ISOTOPES; THRESHOLD-VALUE;

DISEASES;

COPPER; ISOTOPE; TUMOR MARKER; ZINC;

ADULT; AGED; ARTICLE; BLOOD DONOR; BREAST CANCER; CANCER CELL; CANCER MORTALITY; CANCER PATIENT; CHELATION; CHEMICAL COMPOSITION; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; COPPER BLOOD LEVEL; FEMALE; HUMAN; HUMAN TISSUE; LONGITUDINAL STUDY; MALE; MASS SPECTROMETRY; MIDDLE AGED; PILOT STUDY; PRIORITY JOURNAL; PROBABILITY; RECEIVER OPERATING CHARACTERISTIC; YOUNG ADULT; ADOLESCENT; BLOOD; BREAST TUMOR; COLORECTAL TUMOR; METABOLISM; PHENOTYPE; VERY ELDERLY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; COLORECTAL NEOPLASMS; COPPER; FEMALE; HUMANS; ISOTOPES; MALE; MIDDLE AGED; PHENOTYPE; PILOT PROJECTS; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT; ZINC;

EID: 84923096481     PISSN: 17565901     EISSN: 1756591X     Source Type: Journal    
DOI: 10.1039/c4mt00269e     Document Type: Article

References (51)

1. M. C. Linder and C. A. Goode, Biochemistry of copper, Plenum Press, 1991.
2. G. J. Brewer, Copper in medicine, Curr. Opin. Chem. Biol., 2003, 7, 207-212.
3. S. Lutsenko, Human copper homeostasis: a network of interconnected pathways, Curr. Opin. Chem. Biol., 2010, 14, 211-217, DOI: 10.1016/j.cbpa.2010.01.003.
4. P. Carmeliet and R. K. Jain, Angiogenesis in cancer and other diseases, Nature, 2000, 407, 249-257.
5. A. Nasulewicz, A. Mazur and A. Opolski, Role of copper in tumour angiogenesis - clinical implications, J. Trace Elem. Med. Biol., 2004, 18, 1-8.
6. G.-f. Hu, Copper stimulates proliferation of human endothelial cells under culture, J. Cell. Biochem., 1998, 69, 326-335.
7. W. R. Wilson and M. P. Hay, Targeting hypoxia in cancer therapy, Nat. Rev. Cancer, 2011, 11, 393-410.
8. G. L. Semenza, Evaluation of HIF-1 inhibitors as anticancer agents, Drug Discovery Today, 2007, 12, 853-859.
9. R. P. Hill, D. T. Marie-Egyptienne and D. W. Hedley, Cancer Stem Cells, Hypoxia and Metastasis, Semin. Radiat. Oncol., 2009, 19, 106-111.
10. F. Martin, T. Linden, D. M. Katschinski, F. Oehme, I. Flamme, C. K. Mukhopadhyay, K. Eckhardt, J. Tröger, S. Barth and G. Camenisch, Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation, Blood, 2005, 105, 4613-4619.
11. D. B. Milne, Copper intake and assessment of copper status, Am. J. Clin. Nutr., 1998, 67, 1041S-1045S.
12. I. Yücel, F. Arpaci, A. Özet, B. Döner, T. Karayilanoĝlu, A. Sayar and Ö. Berk, Serum copper and zinc levels and copper/zinc ratio in patients with breast cancer, Biol. Trace Elem. Res., 1994, 40, 31-38.
13. Y. Cui, S. Vogt, N. Olson, A. G. Glass and T. E. Rohan, Levels of zinc, selenium, calcium, and iron in benign breast tissue and risk of subsequent breast cancer, Cancer Epidemiol., Biomarkers Prev., 2007, 16, 1682-1685.
14. A. Senra Varela, J. Lopez Saez and D. Quintela Senra, Serum ceruloplasmin as a diagnostic marker of cancer, Cancer Lett., 1997, 121, 139-145.
15. S. Ishida, P. Andreux, C. Poitry-Yamate, J. Auwerx and D. Hanahan, Bioavailable copper modulates oxidative phosphorylation and growth of tumors, Proc. Natl. Acad. Sci. U. S. A., 2013, 110, 19507-19512.
16. G. J. Brewer, Anticopper therapy against cancer and diseases of inflammation and fibrosis, Drug Discovery Today, 2005, 10, 1103-1109.
17. S. A. Lowndes, A. Adams, A. Timms, N. Fisher, J. Smythe, S. M. Watt, S. Joel, F. Donate, C. Hayward and S. Reich, Phase I study of copper-binding agent ATN-224 in patients with advanced solid tumors, Clin. Cancer Res., 2008, 14, 7526-7534.
18. S. Brem, S. A. Grossman, K. A. Carson, P. New, S. Phuphanich, J. B. Alavi, T. Mikkelsen and J. D. Fisher, Phase 2 trial of copper depletion and penicillamine as antiangiogenesis therapy of glioblastoma, Neuro-Oncology, 2005, 7, 246-253.
19. T. Fujii, F. Moynier, J. Blichert-Toft and A. F. Albarede, Density functional theory estimation of isotope fractionation of Fe, Ni, Cu, and Zn among species relevant to geochemical and biological environments, Geochim. Cosmochim. Acta, 2014, 140, 553-576.
20. J. Bigeleisen and M. G. Mayer, Calculation of equilibrium constants for isotopic exchange reactions, J. Chem. Phys., 1947, 15, 261-267.
21. M. Wolfsberg, W. A. VanHook and P. Paneth, Isotope effects: in the chemical, geological, and bio sciences, Springer, New York, 2010, p. 466.
22. F. Albarede, P. Telouk, A. Lamboux, K. Jaouen and V. Balter, Isotopic evidence of unaccounted for Fe and Cu erythropoietic pathways, Metallomics, 2011, 3, 926-933.
23. C. Maréchal, P. Télouk and F. Albarède, Precise analysis of copper and zinc isotopic compositions by plasma-source mass spectrometry, Chem. Geol., 1999, 156, 251-273.
24. S. Hammarström, Semin. Cancer Biol., Elsevier, 1999, vol. 9, pp. 67-81.
25. H.-J. Kim, M.-H. Yu, H. Kim, J. Byun and C. Lee, Noninvasive molecular biomarkers for the detection of colorectal cancer, BMB Rep., 2008, 41, 685-692.
26. K. Y. Fung, E. Nice, I. Priebe, D. Belobrajdic, A. Phatak, L. Purins, B. Tabor, C. Pompeia, T. Lockett and T. E. Adams, Colorectal cancer biomarkers: To be or not to be? Cautionary tales from a road well travelled, World J. Gastroenterol., 2014, 20, 888-898.
27. K. Yonemori, N. Katsumata, A. Noda, H. Uno, M. Yunokawa, E. Nakano, T. Kouno, C. Shimizu, M. Ando and K. Tamura, Development and verification of a prediction model using serum tumor markers to predict the response to chemotherapy of patients with metastatic or recurrent breast cancer, J. Cancer Res. Clin. Oncol., 2008, 134, 1199-1206.
28. K. Jaouen, M. Gibert, A. Lamboux, P. Telouk, F. Fourel, F. Albarède, A. N. Alekseev, E. Crubézy and V. Balter, Is aging recorded in blood Cu and Zn isotope compositions?, Metallomics, 2013, 5, 1016-1024.
29. L. Van Heghe, O. Deltombe, J. Delanghe, H. Depypere and F. Vanhaecke, The influence of menstrual blood loss and age on the isotopic composition of Cu, Fe and Zn in human whole blood, J. Anal. At. Spectrom., 2014, 29, 478-482, DOI: 10.1039/C3JA50269D.
30. K. V. Patel, Semin. Hematol., Elsevier, 2008, vol. 45, pp. 210-217.
31. W. J. Krzanowski and D. J. Hand, ROC curves for continuous data, CRC Press, 2009.
32. I. Zaitseva, V. Zaitsev, G. Card, K. Moshkov, B. Bax, A. Ralph and P. Lindley, The X-ray structure of human serum ceruloplasmin at 3.1 angstrom: Nature of the copper centres, J. Biol. Inorg. Chem., 1996, 1, 15-23.
33. A. K. Boal and A. C. Rosenzweig, Structural biology of copper trafficking, Chem. Rev., 2009, 109, 4760-4779.
34. 44Ca) in inorganic aragonite and cultured planktonic foraminifera, Geochim. Cosmochim. Acta, 2003, 67, 1375-1382.
35. D. J. DePaolo, Calcium isotopic variations produced by biological, kinetic, radiogenic and nucleosynthetic processes, Rev. Mineral. Geochem., 2004, 55, 255-288.
36. O. N. Okorie and P. Dellinger, Lactate: biomarker and potential therapeutic target, Crit. Care Clin., 2011, 27, 299-326.
37. V. Sapin, L. Nicolet, B. Aublet-Cuvelier, F. Sangline, L. Roszyk, B. Dastugue, N. Gazuy, P. Deteix and B. Souweine, Rapid decrease in plasma D-lactate as an early potential predictor of diminished 28-day mortality in critically ill septic shock patients, Clin. Chem. Lab. Med., 2006, 44, 492-496.
38. A. Le, C. R. Cooper, A. M. Gouw, R. Dinavahi, A. Maitra, L. M. Deck, R. E. Royer, D. L. Vander Jagt, G. L. Semenza and C. V. Dang, Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression, Proc. Natl. Acad. Sci. U. S. A., 2010, 107, 2037-2042.
39. S. Walenta, M. Wetterling, M. Lehrke, G. Schwickert, K. Sundfør, E. K. Rofstad and W. Mueller-Klieser, High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers, Cancer Res., 2000, 60, 916-921.
40. M. E. Morris and M. A. Felmlee, Overview of the proton-coupled MCT (SLC16A) family of transporters: characterization, function and role in the transport of the drug of abuse γ-hydroxybutyric acid, AAPS J., 2008, 10, 311-321.
41. J. Piispanen and L. H. Lajunen, Complex Formation Equilibria of Some Aliphatic a-Hydroxycarboxylic Acids. 2. The Study of Copper(II) Complexes, Acta Chem. Scand., 1995, 995, 241-247.
42. R. Portanova, L. H. Lajunen, M. Tolazzi and J. Piispanen, Critical evaluation of stability constants for alpha-hydroxycarboxylic acid complexes with protons and metal ions and the accompanying enthalpy changes. Part II. Aliphatic 2-hydroxycarboxylic acids (IUPAC Technical Report), Pure Appl. Chem., 2003, 75, 495-540.
43. H. Sakamoto, T. Mashima, A. Kizaki, S. Dan, Y. Hashimoto, M. Naito and T. Tsuruo, Glyoxalase I is involved in resistance of human leukemia cells to antitumor agent-induced apoptosis, Blood, 2000, 95, 3214-3218.
44. T. Santel, G. Pflug, N. Y. Hemdan, A. Schäfer, M. Hollenbach, M. Buchold, A. Hintersdorf, I. Lindner, A. Otto and M. Bigl, Curcumin inhibits glyoxalase 1 - a possible link to its antiinflammatory and anti-tumor activity, PLoS One, 2008, 3, e3508.
45. T. Santarius, G. R. Bignell, C. D. Greenman, S. Widaa, L. Chen, C. L. Mahoney, A. Butler, S. Edkins, S. Waris and P. J. Thornalley, GLO1 - a novel amplified gene in human cancer, Genes, Chromosomes Cancer, 2010, 49, 711-725.
46. M. Aramendia, L. Rello, M. Resano and F. Vanhaecke, Isotopic analysis of Cu in serum samples for diagnosis of Wilson's disease: a pilot study, J. Anal. At. Spectrom., 2013, 28, 675-681.
47. P. J. Thornalley and N. Rabbani, Semin. Cell Dev. Biol., Elsevier, 2011, vol. 22, pp. 318-325.
48. K. Bartyik, S. Turi, F. Orosz and E. Karg, Methotrexate inhibits the glyoxalase system in vivo in children with acute lymphoid leukaemia, Eur. J. Cancer, 2004, 40, 2287-2292.
49. A. E. Martell and R. M. Smith, Critical stability constants. Volume 5. First supplement, Plenum, 1982.
50. R. L. Lundblad and F. Macdonald, Handbook of biochemistry and molecular biology, CRC Press, 2010.
51. J. P. van Rossum and D. H. J. Schamhart, Oxidation-reduction (redox) potentiometry in blood in geriatric conditions: A pilot study, Exp. Gerontol., 1991, 26, 37-43.