Glyoxalase I is involved in resistance of human leukemia cells to antitumor agent-induced apoptosis

Blood

Volumn 95, Issue 10, 2000, Pages 3214-3218

  Sakamoto, Hiroshi ^b   Mashima, Tetsuo ^b   Kizaki, Atsuo ^b   Dan, Shingo ^b   Hashimoto, Yuichi ^b   Naito, Mikihiko ^b   Tsuruo, Takashi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

4 BROMOBENZYLGLUTATHIONE CYCLOPENTYL DIESTER; CASPASE; DOXORUBICIN; ETOPOSIDE; GLYOXALASE; GLYOXALASE INHIBITOR; LACTOYLGLUTATHIONE LYASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ANALYSIS; ENZYME INHIBITION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PHENOTYPE; PRIORITY JOURNAL;

EID: 0034657445     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v95.10.3214     Document Type: Article

References (25)

1. Hamada H, Tsuruo T. Functional role for the 170-to 180-kDa glycoprotein specific to drug-resistant tumor cell as revealed by monoclonal antibodies. Proc Natl Acad Sci U S A. 1986;83:7785.
2. Cole SP, Bhardwaj G, Gerlach JH, et al. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science. 1992;258:1650.
3. Sugimoto Y, Tsukahara S, Oh-hara T, Isoe T, Tsuruo T. Decreased expression of DNA topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody. Cancer Res. 1990;50:6925.
4. Takano H, Kohno K, Ono M, Uchida Y, Kuwano M. Increased phosphorylation of DNA topoisomerase II in etoposide-resistant mutants of human cancer KB cells. Cancer Res. 1991;51:3951.
5. Kataoka S, Naito M, Tomida A, Tsuruo T. Resistance to antitumor agent-induced apoptosis in a mutant of human myeloid leukemia U937 cells. Exp Cell Res. 1994;215:199.
6. Gorczyca W, Gong J, Ardelt B, Traganos F, Darzynkiewicz Z. The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents. Cancer Res. 1993; 53:3186.
7. Naito M, Nagashima K, Mashima T, Tsuruo T. Phosphatidylserine externalization is a downstream event of interleukin-1β converting enzyme family protease activation during apoptosis. Blood. 1997;89:2060.
8. Seimiya H, Mashima T, Toho M, Tsuruo T. c-Jun NH2-terminal kinase-mediated activation of interleukin-1β converting enzyme/CED-3-like protease during anticancer drug-induced apoptosis. J Biol Chem. 1997;272:4631.
9. Dan S, Naito M, Seimiya H, Kizaki A, Mashima T, Tsuruo T. Activation of C-Abl tyrosine kinase requires caspase activation and is not involved in JNK/SAPK activation during apoptosis of human monocytic leukemia U937 cells. Oncogens. 1999; 18:1277.
10. Vince R, Daluge S, Wadd WB. Studies of the inhibition of Glyoxalase I by S-substituted glutathiones. J Med Chem. 1971;14:402.
11. Thornalley PJ. Esterification of reduced glutathione. Biochem J. 1991;275:535.
12. Thornalley PJ, Edward LG, Kang Y, et al. Antitumor activity of S-p-bromobenzylglutathione cyclopentyl diester in vitro and in vivo. Biochem Pharmacol. 1996;51:1365.
13. Noguchi K, Naito M, Kataoka S, Yonehara S, Tsuruo T. A recessive mutant of the U937 cell line acquired resistance to anti-Fas and anti-p55 tumor necrosis factor receptor antibody-induced apoptosis. Cell Growth Differ. 1995;6:1271.
14. Seimiya H, Tsuruo T. Differential expression of protein tyrosine phosphatase genes during phorbol ester-induced differentiation of human leukemia U937 cells. Cell Growth Differ, 1993;4:1033.
15. Shinohara M, Thornalley PJ, Giardino I, et al. Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increase in macromolecular endocytosis. J Clin Invest. 1998;101:1142.
16. Tsuruo T, Iida-Saito H, Kawabata H, Oh-hara T, Hamada H, Utakoji T. Characteristics of resistance to adriamycin in human myelogenous leukemia K562 resistant to adriamycin and in isolated clones. Jpn J Cancer Res. 1986;77:682.
17. Riss TL, Moravec RA. Comparison of MTT, XTT and a novel tetrazolium compound MTS for in vitro proliferation and chemosensitivtty assays. Mol Biol Cell. 1992;3:184.
18. Ichijo H, Nishida E, Irie K, et al. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science. 1997;275:90.
19. Lo TW, Westwood ME, McLellan AC, Selwood T, Thornalley PJ. Binding and modification of proteins by methylglyoxal under physiological conditions: a kinetic and mechanistic study with N-alpha-acetylarginine, N-alpha-acetylcysteine, and N-alpha-acetyllysine, and bovine serum albumin. J Biol Chem. 1994;269:32,299.
20. Thornalley PJ. The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life. Biochem J. 1990;269:1.
21. Ranganathan S, Tew KD. Analysis of glyoxalase-I from normal and tumor tissue from human colon. Biochim Biophys Acta. 1993;1182:311.
22. Di Ilio C, Angelucci S, Pennelli A, Zezza A, Tenaglia R, Sacchetta P. Glyoxalase activities in tumor and non-tumor human urogenital tissues. Cancer Lett. 1995;96:189.
23. Ranganathan S, Walsh ES, Tew KD. Glyoxalase I in detoxification: studies using a glyoxalase I transfectant cell line. Biochem J. 1995;309:127.
24. Davidson SD, Cherry JP, Choudhury MS, Tazaki H, Mallouh C, Konno S. Glyoxalase I activity in human prostate cancer: a potential marker and importance in chemotherapy. J Urol. 1999;161: 690.
25. Kavarana MJ, Kovaleva EG, Creighton DJ, Wollman MB, Eiseman JL. Mechanism-based competitive inhibitors of glyoxalase I: intracellular delivery, in vitro antitumor activities, and stabilities in human serum and mouse serum. J Med Chem. 1999;42:221.