Atoh1 gene therapy in the cochlea for hair cell regeneration

Expert Opinion on Biological Therapy

Volumn 15, Issue 3, 2015, Pages 417-430

  Richardson, Rachael T ^a   Atkinson, Patrick J ^b  

^a Bionics Institute   (Australia)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenovirus; Atoh1; Cochlea; Gene therapy; Hair cell; Hearing loss; Regeneration; Supporting cell

Indexed keywords

ACOUSTIC NERVE FIBER; ATOH1 GENE; CELL MATURATION; CELL REGENERATION; CELL TRANSDIFFERENTIATION; COCHLEA; COCHLEA DUCT; DOWN REGULATION; EFFERENT NERVE; ENDOLYMPH; GENE; GENE DELETION; GENE EXPRESSION; GENE THERAPY; HAIR CELL; HEARING IMPAIRMENT; HUMAN; NEUROEPITHELIUM; NONHUMAN; OUTER HAIR CELL; REVIEW; SPIRAL GANGLION; TIGHT JUNCTION; ANIMAL; GENETICS; PHYSIOLOGY; PROCEDURES; REGENERATION;

ADENOVIRIDAE; MAMMALIA;

ATOH1 PROTEIN, HUMAN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; COCHLEA; GENETIC THERAPY; HAIR CELLS, AUDITORY; HUMANS; REGENERATION;

EID: 84923088575     PISSN: 14712598     EISSN: 17447682     Source Type: Journal    
DOI: 10.1517/14712598.2015.1009889     Document Type: Review

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