Hair cell regeneration after ATOH1 gene therapy in the cochlea of profoundly deaf adult guinea pigs

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Atkinson, Patrick J ^a,b   Wise, Andrew K ^a,b   Flynn, Brianna O ^a   Nayagam, Bryony A ^a,b   Richardson, Rachael T ^a,b  

^a Bionics Institute   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROGENIN 1; NEUROTROPHIN 3; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ATOH1; UNCLASSIFIED DRUG; ATOH1 PROTEIN, MOUSE; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR;

ACOUSTIC NERVE FIBER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOH1 GENE; AUDITORY THRESHOLD; CELL COUNT; CELL DENSITY; CELL REGENERATION; CELL TRANSDIFFERENTIATION; DRUG EFFICACY; DRUG RESPONSE; FEMALE; GENE; GENE EXPRESSION; HAIR CELL; HUMAN ADENOVIRUS 5; INNER EAR HEARING LOSS; MALE; NONHUMAN; PHENOTYPE; SENSORY NERVE CELL; SYNAPSE; TREATMENT DURATION; VIRAL GENE DELIVERY SYSTEM; VIRUS TITRATION; ANIMAL; DEAFNESS; GENE THERAPY; GENETICS; GUINEA PIG; HEARING; MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REGENERATION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; DEAFNESS; FEMALE; GENETIC THERAPY; GUINEA PIGS; HAIR CELLS, AUDITORY; HEARING; MALE; MICE; REGENERATION; SYNAPSES;

EID: 84904488877     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102077     Document Type: Article

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