Evaluation of Antiobesity Effect of Mangiferin in Adipogenesis-Induced Human Mesenchymal Stem Cells by Assessing Adipogenic Genes

Journal of Food Biochemistry

Volumn 39, Issue 1, 2015, Pages 28-38

  Subash Babu, P ^a   Alshatwi, Ali A ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL DEATH; FATTY ACIDS; MOLECULAR WEIGHT; POLYMERASE CHAIN REACTION; TRANSCRIPTION;

ADIPOCYTE DIFFERENTIATION; FATTY ACID-BINDING PROTEINS; HUMAN MESENCHYMAL STEM CELLS; HUMAN MESENCHYMAL STEM CELLS (HMSCS); PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PREADIPOCYTE DIFFERENTIATION; QUANTITATIVE REVERSE TRANSCRIPTION-POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR ALPHA;

STEM CELLS;

EID: 84923080040     PISSN: 01458884     EISSN: 17454514     Source Type: Journal    
DOI: 10.1111/jfbc.12101     Document Type: Article

References (46)

1. Arner, P. 2005. Insulin resistance in type 2 diabetes - role of the adipokines. Curr. Mol. Med. 5, 333-339.
2. Boone, C., Mourot, J., Gregiore, F. and Remacle, C. 2000. The adipose conversion process: Regulation by extracellular and intracellular factors. Reprod. Nutr. Dev. 40, 325-358.
3. Bradford, M.M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72, 248-254.
4. Burris, T.P., Pelton, P.D., Zhou, L., Osborne, M.C., Cryan, E. and Demarest, K.T. 1999. A novel method for analysis of nuclear receptor function at natural promoters: Peroxisome proliferator-activated receptor gamma agonist actions on aP2 gene expression detected using branched DNA messenger RNA quantitation. Mol. Endocrinol. 13, 410-417.
5. Cai, Y.Z., Sun, M., Xing, J., Luo, Q. and Corke, H. 2006. Structure-radical scavenging activity relationships of phenolic compounds from traditional Chinese medicinal plants. Life Sci. 78, 2872-2888.
6. Caplan, A.I. 2005. Review: Mesenchymal stem cells: Cell-based reconstructive therapy in orthopedics. Tissue Eng. 11(7-8), 1198-1211.
7. Caplan, A.I. 2007. Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. J. Cell. Physiol. 213, 341-347.
8. Choi, E.J. 2007. Hesperetin induced G1-phase cell cycle arrest in human breast cancer MCF-7 cells: Involvement of CDK4 and p21. Nutr. Cancer 59, 115-119.
9. David, G.P., Li, L. and Zhang, W. 2010. Bitter melon (Momordica charantia) triterpenoid extract reduces preadipocyte viability, lipid accumulation and adiponectin expression in 3T3-L1 cells. Food Chem. Toxicol. 48, 1619-1626.
10. Ding, S.T., McNeel, R.L. and Mersmann, H.J. 1999. Expression of porcine adipocyte transcripts: Tissue distribution and differentiation in vitro and in vivo. Comp. Biochem. Physiol. 123, 307-318.
11. Duncan, B.D. 1957. Multiple range test for correlated and heteroscedastic means. Biometrics 13, 359-364.
12. Eckel, R.H., Grundy, S.M. and Zimmet, P.Z. 2005. The metabolism syndrome. Lancet 365, 1415-1428.
13. Garg, A., Garg, S., Zaneveld, L.J. and Singla, A.K. 2001. Chemistry and pharmacology of the citrus bioflavonoid hesperidin. Phytother. Res. 15, 655-669.
14. Gil-Campos, M., Canete, R.R. and Gil, A. 2004. Adiponectin, the missing link in insulin resistance and obesity. Clin. Nutr. 23, 963-974.
15. Glascott, P., Gilford, J.E. and Farber, J. 1992. Effects of vitamin E on the killing of cultured hepatocytes by tert-butyl hydroperoxides. Mol. Pharmacol. 41, 1155-1162.
16. Goldstein, D.J. 1992. Beneficial health effects of modest weight loss. Int. J. Obes. Relat. Metab. Disord. 16, 397-415.
17. Green, H. and Kehinde, O. 1976. Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells. Cell 7, 105-113.
18. Greenberg, A.S. and McDaniel, M.L. 2002. Identifying the links between obesity, insulin resistance and beta cell function: Potential role of adipocyte-derived cytokines in the pathogenesis of type 2 diabetes. Eur. J. Clin. Invest. 32, 24-34.
19. Gregoire, F.M., Smas, C.M. and Sul, H.S. 1998. Understanding adipocyte differentiation. Physiol. Rev. 78, 783-809.
20. Halleux, C.M., Takahashi, M., Delporte, M.L., Detry, R., Funahashi, T., Matsuzawa, Y. and Brichard, S.M. 2001. Secretion of adiponectin and regulation of apM1 gene expression in human visceral adipose tissue. Biochem. Biophys. Res. Commun. 288, 1102-1107.
21. Hotamisligil, G. and Spiegelman, B. 1994. Tumor necrosis factor-a: A key component of the obesity-diabetes link. Diabetes 43, 1271-1278.
22. Hotamisligil, G.S., Shargill, N.S. and Spiegelman, B.M. 1993. Adipose expression of tumor necrosis factor-alpha: Direct role in obesity linked insulin resistance. Science 259, 87-91.
23. Hung, S.C., Chen, N.J., Hsieh, S.L., Li, H., Ma, H.L. and Lo, W.H. 2002. Isolation and characterization of size-sieved stem cells from human bone marrow. Stem Cells 20, 249-258.
24. Ivanka, S., Leopold, J., Albena, S., Albert, K., Stoyanka, G. and Lien, H. 2008. Antioxidant activity of the polyphenol mangiferin. EJEAFChe. 7(13), 2706-2716.
25. Jong, W.Y. 2010. Possible anti-obesity therapeutics from nature - A review. Phytochemistry 71, 1625-1641.
26. Kim, H.J., Jeon, S.M., Lee, M.K., Cho, Y.Y., Kwon, E.Y., Lee, J.H. and Choi, M.S. 2010. Comparison of hesperetin and its metabolites for cholesterol-lowering and antioxidative efficacy in hypercholesterolemic hamsters. J. Med. Food 13, 808-814.
27. Kim, M.S., Kim, J.K., Kwon, D.Y. and Park, R. 2004. Anti-adipogenic effects of Garcinia extract on the lipid droplet accumulation and the expression of transcription factor. Biofactors 22, 193-196.
28. Lin, Y., Vermeer, M.A., Bos, W., Van, B.L., Schuurbiers, E., Miret-Catalan, S. and Trautwein, E.A. 2011. Molecular structures of citrus flavonoids determine their effects on lipid metabolism in HepG2 cells by primarily suppressing apoB secretion. J. Agric. Food Chem. 59, 4496-4503.
29. Lowell, B.B. 1999. PPARg: An essential regulator of adipogenesis and modulator of fat cell function. Cell 99, 239-242.
30. Moller, D.E. 2000. Potential role of TNF-a in the pathogenesis of insulin resistance and type 2 diabetes. Trends Endocrinol. Metab. 11, 212-217.
31. Mosmann, T. 1983. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Methods 65, 55-63.
32. Nichols, L.A., Jackson, D.E., Manthey, J.A., Shukla, S.D. and Holland, L.J. 2011. Citrus flavonoids repress the mRNA for stearoyl-CoA desaturase, a key enzyme in lipid synthesis and obesity control, in rat primary hepatocytes. Lipids Health Dis. 10, 36.
33. Phillips, J.E., Timothy, A.P., Francis, P.C. and García, A.J. 2010. Human mesenchymal stem cell differentiation on self-assembled monolayers presenting different surface chemistries. Acta Biomater. 6, 12-20.
34. Pittenger, M.F., Mackay, A.M., Beck, S.C., Jaiswal, R.K., Douglas, R., Mosca, J.D., Moorman, M.A., Simonetti, D.W., Craig, S. and Marshak, D.R. 1999. Multilineage potential of adult human mesenchymal stem cells. Science 284, 143-147.
35. Rajala, M.W., Qi, Y., Patel, H.R., Takahashi, N., Banerjee, R., Pajvani, U.B., Sinha, M.K., Gingerich, R.L., Scherer, P.E. and Ahima, R.S. 2004. Regulation of resistin expression and circulating levels in obesity, diabetes and fasting. Diabetes 53, 1671-1679.
36. Shan, T.Z., Wang, Y.Z. and Li, M. 2006. Cloning of lipoprotein lipase (LPL) gene of swine and the difference of LPL gene expression at different avoirdupois stages. J. Agric. Biotechnol. 14, 151-155.
37. Srujana, R., Della-Fera, M.A. and Baile, C.A. 2008. Phytochemicals and regulation of the adipocyte life cycle. J. Nutr. Biochem. 19, 717-726.
38. Steppan, C.M., Bailey, S.T., Brown, E.R., Banerjee, J.B., Wright, C.M., Patel, H.R., Ahina, R.S. and Lazar, M.A. 2001. The hormone resistin links obesity to diabetes. Nature 409, 307-312.
39. Stern, J.S., Hirsch, J., Blair, S.N., Foreyt, J.P., Frank, A., Kumanyika, S.K., Madans, J.H., Marlatt, G.A., Stjeor, S.T. and Stunkard, A.J. 1995. Weighing the options: Criteria for evaluating weight-management programs. The committee to develop criteria for evaluating the outcomes of approaches to prevent and treat obesity. Obes. Res. 3, 591-604.
40. Subash-Babu, P. and Alshatwi, A.A. 2012. Aloe-emodin inhibits adipocyte differentiation and maturation during in vitro human mesenchymal stem cell adipogenesis. J. Biochem. Mol. Toxicol. 26, 291-300.
41. Taylor, S.M. and Jones, P.A. 1979. Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine. Cell 17, 771-779.
42. Visscher, T.L. and Seidell, J.C. 2001. The public health impact of obesity. Annu. Rev. Public Health 22, 355-375.
43. Wadden, T.A. 1993. Treatment of obesity by moderate and severe caloric restriction. Results of clinical research trials. Ann. Intern. Med. 119, 688-693.
44. Weinstock, P.H., Levak-Frank, S., Hudgins, L.C., Radner, H., Friedman, J.M., Zechner, R. and Breslow, J.L. 1997. Lipoprotein lipase controls fatty acid entry into adipose tissue but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase. Proc. Natl. Acad. Sci. USA 94, 10261-10266.
45. Wise, L. and Green, H. 1979. Participation of one isozyme of cytosolic glycerophosphate in adipose conversation to 3T3 cells. J. Biol. Chem. 254, 273-275.
46. Zhao, L., Jung-Heun, H., Okla, M. and Chung, S. 2014. Activation of autophagy and AMPK by gamma-tocotrienol suppresses the adipogenesis in human adipose derived stem cells. Mol. Nutr. Food Res. 58, 569-579.