-
1
-
-
0033594989
-
Thermal versus guanidine-induced unfolding of ubiquitin. An analysis in terms of the contributions from charge-charge interactions to protein stability
-
Ibarra-Molero, B., Loladze, V. V., Makhatadze, G. I. & Sanchez-Ruiz, J. M. Thermal versus guanidine-induced unfolding of ubiquitin. An analysis in terms of the contributions from charge-charge interactions to protein stability. Biochemistry 38, 8138-8149 (1999).
-
(1999)
Biochemistry
, vol.38
, pp. 8138-8149
-
-
Ibarra-Molero, B.1
Loladze, V.V.2
Makhatadze, G.I.3
Sanchez-Ruiz, J.M.4
-
2
-
-
12744263121
-
Simultaneous determination of protein structure and dynamics
-
Lindorff-Larsen, K., Best, R. B., Depristo, M. A., Dobson, C. M. & Vendruscolo, M. Simultaneous determination of protein structure and dynamics. Nature 433, 128-132 (2005).
-
(2005)
Nature
, vol.433
, pp. 128-132
-
-
Lindorff-Larsen, K.1
Best, R.B.2
Depristo, M.A.3
Dobson, C.M.4
Vendruscolo, M.5
-
4
-
-
0035292759
-
Themes and variations on ubiquitylation
-
Weissman, A. M. Themes and variations on ubiquitylation. Nat. Rev. Mol. Cell Biol. 2, 169-178 (2001).
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 169-178
-
-
Weissman, A.M.1
-
5
-
-
70349441058
-
Ubiquitin-binding domains-from structures to functions
-
Dikic, I., Wakatsuki, S. & Walters, K. J. Ubiquitin-binding domains-from structures to functions. Nat. Rev. Mol. Cell Biol. 10, 659-671 (2009).
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 659-671
-
-
Dikic, I.1
Wakatsuki, S.2
Walters, K.J.3
-
6
-
-
0024976878
-
Brain diseases. Ubiquitous variations in nerves
-
Gallo, J. M. & Anderton, B. H. Brain diseases. Ubiquitous variations in nerves. Nature 337, 687-688 (1989).
-
(1989)
Nature
, vol.337
, pp. 687-688
-
-
Gallo, J.M.1
Anderton, B.H.2
-
7
-
-
0023140474
-
Ubiquitin is a component of paired helical filaments in Alzheimer's disease
-
Mori, H., Kondo, J. & Ihara, Y. Ubiquitin is a component of paired helical filaments in Alzheimer's disease. Science 235, 1641-1644 (1987).
-
(1987)
Science
, vol.235
, pp. 1641-1644
-
-
Mori, H.1
Kondo, J.2
Ihara, Y.3
-
8
-
-
3142514201
-
Protein aggregation and neurodegenerative disease
-
Ross, C. A. & Poirier, M. A. Protein aggregation and neurodegenerative disease. Nat. Med. 10(Suppl): S10-S17 (2004).
-
(2004)
Nat. Med.
, vol.10
, pp. S10-S17
-
-
Ross, C.A.1
Poirier, M.A.2
-
9
-
-
65549142204
-
A role for ubiquitin in selective autophagy
-
Kirkin, V., McEwan, D. G., Novak, I. & Dikic, I. A role for ubiquitin in selective autophagy. Mol. Cell 34, 259-269 (2009).
-
(2009)
Mol. Cell
, vol.34
, pp. 259-269
-
-
Kirkin, V.1
McEwan, D.G.2
Novak, I.3
Dikic, I.4
-
10
-
-
0028230147
-
Thermodynamics of ubiquitin unfolding
-
Wintrode, P. L., Makhatadze, G. I. & Privalov, P. L. Thermodynamics of ubiquitin unfolding. Proteins 18, 246-253 (1994).
-
(1994)
Proteins
, vol.18
, pp. 246-253
-
-
Wintrode, P.L.1
Makhatadze, G.I.2
Privalov, P.L.3
-
11
-
-
78650963274
-
Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions
-
Olzscha, H. et al. Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions. Cell 144, 67-78 (2011).
-
(2011)
Cell
, vol.144
, pp. 67-78
-
-
Olzscha, H.1
-
12
-
-
0042467550
-
Rationalization of the effects of mutations on peptide and protein aggregation rates
-
Chiti, F., Stefani, M., Taddei, N., Ramponi, G. & Dobson, C. M. Rationalization of the effects of mutations on peptide and protein aggregation rates. Nature 424, 805-808 (2003).
-
(2003)
Nature
, vol.424
, pp. 805-808
-
-
Chiti, F.1
Stefani, M.2
Taddei, N.3
Ramponi, G.4
Dobson, C.M.5
-
13
-
-
79952308169
-
Decreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS
-
Vassall, K. A. et al. Decreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS. Proc. Natl Acad. Sci. USA 108, 2210-2215 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 2210-2215
-
-
Vassall, K.A.1
-
14
-
-
80052263787
-
The effects of shear flow on protein structure and function
-
Bekard, I. B., Asimakis, P., Bertolini, J. & Dunstan, D. E. The effects of shear flow on protein structure and function. Biopolymers 95, 733-745 (2011).
-
(2011)
Biopolymers
, vol.95
, pp. 733-745
-
-
Bekard, I.B.1
Asimakis, P.2
Bertolini, J.3
Dunstan, D.E.4
-
15
-
-
0032528012
-
Modulation of calmodulin function by ubiquitin-calmodulin ligase and identification of the responsible ubiquitylation site in vertebrate calmodulin
-
Laub, M. et al. Modulation of calmodulin function by ubiquitin-calmodulin ligase and identification of the responsible ubiquitylation site in vertebrate calmodulin. Eur. J. Biochem. 255, 422-431 (1998).
-
(1998)
Eur. J. Biochem.
, vol.255
, pp. 422-431
-
-
Laub, M.1
-
16
-
-
80054033461
-
A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles
-
Wagner, S. A. et al. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. Mol. Cell. Proteomics 10, M111.013284 (2011).
-
(2011)
Mol. Cell. Proteomics
, vol.10
, pp. M111013284
-
-
Wagner, S.A.1
-
17
-
-
84864482745
-
Probing exchange kinetics and atomic resolution dynamics in high-molecular-weight complexes using dark-state exchange saturation transfer NMR spectroscopy
-
Fawzi, N. L., Ying, J., Torchia, D. A. & Clore, G. M. Probing exchange kinetics and atomic resolution dynamics in high-molecular-weight complexes using dark-state exchange saturation transfer NMR spectroscopy. Nat. Protoc. 7, 1523-1533 (2012).
-
(2012)
Nat. Protoc.
, vol.7
, pp. 1523-1533
-
-
Fawzi, N.L.1
Ying, J.2
Torchia, D.A.3
Clore, G.M.4
-
18
-
-
83055176454
-
Atomic-resolution dynamics on the surface of amyloid-b protofibrils probed by solution NMR
-
Fawzi, N. L., Ying, J., Ghirlando, R., Torchia, D. A. & Clore, G. M. Atomic-resolution dynamics on the surface of amyloid-b protofibrils probed by solution NMR. Nature 480, 268-272 (2011).
-
(2011)
Nature
, vol.480
, pp. 268-272
-
-
Fawzi, N.L.1
Ying, J.2
Ghirlando, R.3
Torchia, D.A.4
Clore, G.M.5
-
19
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya, Y. et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J. 19, 5720-5728 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
-
20
-
-
84883830467
-
Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy
-
Ichimura, Y. et al. Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Mol. Cell 51, 618-631 (2013).
-
(2013)
Mol. Cell
, vol.51
, pp. 618-631
-
-
Ichimura, Y.1
-
21
-
-
0032898636
-
Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy
-
Tanida, I. et al. Apg7p/Cvt2p: a novel protein-activating enzyme essential for autophagy. Mol. Biol. Cell 10, 1367-1379 (1999).
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 1367-1379
-
-
Tanida, I.1
-
22
-
-
33750219981
-
A ubiquitin ligase complex assembles linear polyubiquitin chains
-
Kirisako, T. et al. A ubiquitin ligase complex assembles linear polyubiquitin chains. EMBO J. 25, 4877-4887 (2006).
-
(2006)
EMBO J.
, vol.25
, pp. 4877-4887
-
-
Kirisako, T.1
-
23
-
-
84906972203
-
Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway
-
Kageyama, S. et al. Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway. J. Biol. Chem. 289, 24944-24955 (2014).
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 24944-24955
-
-
Kageyama, S.1
-
24
-
-
84879602122
-
The parallel reaction monitoring method contributes to a highly sensitive polyubiquitin chain quantification
-
Tsuchiya, H., Tanaka, K. & Saeki, Y. The parallel reaction monitoring method contributes to a highly sensitive polyubiquitin chain quantification. Biochem. Biophys. Res. Commun. 436, 223-229 (2013).
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.436
, pp. 223-229
-
-
Tsuchiya, H.1
Tanaka, K.2
Saeki, Y.3
-
25
-
-
78049495046
-
Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: A potential role for protein aggregation in autophagic substrate selection
-
Riley, B. E. et al. Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection. J. Cell Biol. 191, 537-552 (2010).
-
(2010)
J. Cell Biol.
, vol.191
, pp. 537-552
-
-
Riley, B.E.1
-
26
-
-
79251582498
-
Calorimetric study of a series of designed repeat proteins: Modular structure and modular folding
-
Cortajarena, A. L. & Regan, L. Calorimetric study of a series of designed repeat proteins: modular structure and modular folding. Protein Sci. 20, 336-340 (2011).
-
(2011)
Protein Sci.
, vol.20
, pp. 336-340
-
-
Cortajarena, A.L.1
Regan, L.2
-
27
-
-
33646375442
-
Deposition diseases and 3D domain swapping
-
Bennett, M. J., Sawaya, M. R. & Eisenberg, D. Deposition diseases and 3D domain swapping. Structure 14, 811-824 (2006).
-
(2006)
Structure
, vol.14
, pp. 811-824
-
-
Bennett, M.J.1
Sawaya, M.R.2
Eisenberg, D.3
-
28
-
-
79959830883
-
Single-molecule fluorescence reveals sequence-specific misfolding in multidomain proteins
-
Borgia, M. B. et al. Single-molecule fluorescence reveals sequence-specific misfolding in multidomain proteins. Nature 474, 662-665 (2011).
-
(2011)
Nature
, vol.474
, pp. 662-665
-
-
Borgia, M.B.1
-
29
-
-
28644437048
-
The importance of sequence diversity in the aggregation and evolution of proteins
-
Wright, C. F., Teichmann, S. A., Clarke, J. & Dobson, C. M. The importance of sequence diversity in the aggregation and evolution of proteins. Nature 438, 878-881 (2005).
-
(2005)
Nature
, vol.438
, pp. 878-881
-
-
Wright, C.F.1
Teichmann, S.A.2
Clarke, J.3
Dobson, C.M.4
-
30
-
-
79955565416
-
Minimum energy compact structures in force-quench polyubiquitin folding are domain swapped
-
Xia, F., Thirumalai, D. & Gräter, F. Minimum energy compact structures in force-quench polyubiquitin folding are domain swapped. Proc. Natl Acad. Sci. USA 108, 6963-6968 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 6963-6968
-
-
Xia, F.1
Thirumalai, D.2
Gräter, F.3
-
31
-
-
0346734137
-
Myoglobin forms amyloid fibrils by association of unfolded polypeptide segments
-
Fändrich, M. et al. Myoglobin forms amyloid fibrils by association of unfolded polypeptide segments. Proc. Natl Acad. Sci. USA 100, 15463-15468 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 15463-15468
-
-
Fändrich, M.1
-
32
-
-
0344394335
-
Multiple steps during the formation of beta-lactoglobulin fibrils
-
Arnaudov, L. N., de Vries, R., Ippel, H. & van Mierlo, C. P. Multiple steps during the formation of beta-lactoglobulin fibrils. Biomacromolecules 4, 1614-1622 (2003).
-
(2003)
Biomacromolecules
, vol.4
, pp. 1614-1622
-
-
Arnaudov, L.N.1
De Vries, R.2
Ippel, H.3
Van Mierlo, C.P.4
-
33
-
-
50649116818
-
Misfolded proteins partition between two distinct quality control compartments
-
Kaganovich, D., Kopito, R. & Frydman, J. Misfolded proteins partition between two distinct quality control compartments. Nature 454, 1088-1095 (2008).
-
(2008)
Nature
, vol.454
, pp. 1088-1095
-
-
Kaganovich, D.1
Kopito, R.2
Frydman, J.3
-
34
-
-
84879625944
-
Ubiquitin conjugation triggers misfolded protein sequestration into quality control foci when Hsp70 chaperone levels are limiting
-
Shiber, A., Breuer, W., Brandeis, M. & Ravid, T. Ubiquitin conjugation triggers misfolded protein sequestration into quality control foci when Hsp70 chaperone levels are limiting. Mol. Biol. Cell 24, 2076-2087 (2013).
-
(2013)
Mol. Biol. Cell
, vol.24
, pp. 2076-2087
-
-
Shiber, A.1
Breuer, W.2
Brandeis, M.3
Ravid, T.4
-
35
-
-
41249090880
-
Monoubiquitylation of alpha-synuclein by seven in absentia homolog (SIAH) promotes its aggregation in dopaminergic cells
-
Rott, R. et al. Monoubiquitylation of alpha-synuclein by seven in absentia homolog (SIAH) promotes its aggregation in dopaminergic cells. J. Biol. Chem. 283, 3316-3328 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 3316-3328
-
-
Rott, R.1
-
36
-
-
79952355107
-
Selective autophagy mediated by autophagic adapter proteins
-
Johansen, T. & Lamark, T. Selective autophagy mediated by autophagic adapter proteins. Autophagy 7, 279-296 (2011).
-
(2011)
Autophagy
, vol.7
, pp. 279-296
-
-
Johansen, T.1
Lamark, T.2
-
37
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
Mizushima, N., Levine, B., Cuervo, A. M. & Klionsky, D. J. Autophagy fights disease through cellular self-digestion. Nature 451, 1069-1075 (2008).
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
38
-
-
27944504351
-
P62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
-
Bjørkøy, G. et al. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J. Cell Biol. 171, 603-614 (2005).
-
(2005)
J. Cell Biol.
, vol.171
, pp. 603-614
-
-
Bjørkøy, G.1
-
39
-
-
67049158203
-
Rheb controls misfolded protein metabolism by inhibiting aggresome formation and autophagy
-
Zhou, X. et al. Rheb controls misfolded protein metabolism by inhibiting aggresome formation and autophagy. Proc. Natl Acad. Sci. USA 106, 8923-8928 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 8923-8928
-
-
Zhou, X.1
-
40
-
-
0036830343
-
Impairment of proteasome structure and function in aging
-
Carrard, G., Bulteau, A. L., Petropoulos, I. & Friguet, B. Impairment of proteasome structure and function in aging. Int. J. Biochem. Cell Biol. 34, 1461-1474 (2002).
-
(2002)
Int. J. Biochem. Cell Biol.
, vol.34
, pp. 1461-1474
-
-
Carrard, G.1
Bulteau, A.L.2
Petropoulos, I.3
Friguet, B.4
-
41
-
-
33745026738
-
Autophagy and aging: The importance of maintaining clean cells
-
Cuervo, A. M. et al. Autophagy and aging: the importance of maintaining "clean" cells. Autophagy 1, 131-140 (2005).
-
(2005)
Autophagy
, vol.1
, pp. 131-140
-
-
Cuervo, A.M.1
-
42
-
-
80052303130
-
Autophagy and aging
-
Rubinsztein, D. C., Marinõ, G. & Kroemer, G. Autophagy and aging. Cell 146, 682-695 (2011).
-
(2011)
Cell
, vol.146
, pp. 682-695
-
-
Rubinsztein, D.C.1
Marinõ, G.2
Kroemer, G.3
-
43
-
-
57749098600
-
Amyloid formation by globular proteins under native conditions
-
Chiti, F. & Dobson, C. M. Amyloid formation by globular proteins under native conditions. Nat. Chem. Biol. 5, 15-22 (2009).
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 15-22
-
-
Chiti, F.1
Dobson, C.M.2
-
44
-
-
5644259751
-
Structural basis for distinct roles of Lys63-and Lys48-linked polyubiquitin chains
-
Tenno, T. et al. Structural basis for distinct roles of Lys63-and Lys48-linked polyubiquitin chains. Genes Cells 9, 865-875 (2004).
-
(2004)
Genes Cells
, vol.9
, pp. 865-875
-
-
Tenno, T.1
-
45
-
-
65349110554
-
Ligand-directed tosyl chemistry for protein labeling in vivo
-
Tsukiji, S., Miyagawa, M., Takaoka, Y., Tamura, T. & Hamachi, I. Ligand-directed tosyl chemistry for protein labeling in vivo. Nat. Chem. Biol. 5, 341-343 (2009).
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 341-343
-
-
Tsukiji, S.1
Miyagawa, M.2
Takaoka, Y.3
Tamura, T.4
Hamachi, I.5
-
46
-
-
0032004888
-
An expression system of rat calmodulin using T7 phage promoter in Escherichia coli
-
Hayashi, N., Matsubara, M., Takasaki, A., Titani, K. & Taniguchi, H. An expression system of rat calmodulin using T7 phage promoter in Escherichia coli. Protein Expr. Purif. 12, 25-28 (1998).
-
(1998)
Protein Expr. Purif.
, vol.12
, pp. 25-28
-
-
Hayashi, N.1
Matsubara, M.2
Takasaki, A.3
Titani, K.4
Taniguchi, H.5
-
47
-
-
77954437030
-
Purification, crystallization and preliminary crystallographic studies of Lys48-linked polyubiquitin chains
-
Morimoto, D. et al. Purification, crystallization and preliminary crystallographic studies of Lys48-linked polyubiquitin chains. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66, 834-837 (2010).
-
(2010)
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun.
, vol.66
, pp. 834-837
-
-
Morimoto, D.1
-
48
-
-
31544445747
-
Shear flow induces amyloid fibril formation
-
Hill, E. K., Krebs, B., Goodall, D. G., Howlett, G. J. & Dunstan, D. E. Shear flow induces amyloid fibril formation. Biomacromolecules 7, 10-13 (2006).
-
(2006)
Biomacromolecules
, vol.7
, pp. 10-13
-
-
Hill, E.K.1
Krebs, B.2
Goodall, D.G.3
Howlett, G.J.4
Dunstan, D.E.5
-
50
-
-
41149139755
-
Investigation of structural transition of regenerated silk fibroin aqueous solution by Rheo-NMR Spectroscopy
-
Ohgo, K., Bagusat, F., Asakura, T. & Scheler, U. Investigation of structural transition of regenerated silk fibroin aqueous solution by Rheo-NMR Spectroscopy. J. Am. Chem. Soc. 130, 4182-4186 (2008).
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 4182-4186
-
-
Ohgo, K.1
Bagusat, F.2
Asakura, T.3
Scheler, U.4
|