Global chemical profiling based quality evaluation approach of rhubarb using ultra performance liquid chromatography with tandem quadrupole time-of-flight mass spectrometry

Journal of Separation Science

Volumn 38, Issue 3, 2015, Pages 511-522

  Zhang, Li ^a   Liu, Haiyu ^a   Qin, Lingling ^a   Zhang, Zhixin ^a   Wang, Qing ^a   Zhang, Qingqing ^a   Lu, Zhiwei ^a   Wei, Shengli ^a   Gao, Xiaoyan ^a   Tu, Pengfei ^b  

^a BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Column performance evaluation; Global chemical profiling; Hierarchical cluster analysis; Rhubarb; Similarity evaluation

Indexed keywords

CHEMICAL DETECTION; HIERARCHICAL CLUSTERING; HIERARCHICAL SYSTEMS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PLANTS (BOTANY);

CHEMICAL PROFILING; COLUMN PERFORMANCE; DETECTION OF CHEMICALS; QUALITY EVALUATION; REFERENCE STANDARD; RHUBARB; SIMILARITY EVALUATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

QUALITY CONTROL;

1 4 (HYDROXYLBENZOYL) GLUCOPYRANOSIDE; 2,5 DIMETHYL 7 HYDROXYCHROMONE O (2' O GALLOYL 6' O GALLOYL) GLUCOPYRANOSIDE; 4 (4' HYDROXYPHENYL) 2 BUTANONE 4' O BETA DEXTRO GLUCOPYRANOSIDE; ALOE EMODIN 8 O (6' O MALONYL) GLUCOPYRANOSIDE; ALOE EMODIN O GLUCOPYRANOSIDE; ALOIN; CARBOXYL CHRYSOPHANOL O GLUCOSE; CATECHIN; CATECHIN 3 O BETA DEXTRO GLUCOPYRANOSIDE; EMODIN O ACETYL GLUCOPYRANOSIDE; EMODIN O GLUCOPYRANOSIDE; GALLIC ACID O GALLOYL GLUCOPYRANOSIDE; GALLIC ACID O GLUCOPYRANOSIDE; HESPERETIN 5 O GLUCOPYRANOSIDE; ISOLINDLEYIN; LINDLEYIN; PLANT EXTRACT; PROCYANIDIN B; PROCYANIDIN B 1 3 O GALLATE; PROCYANIDIN B O GALLATE; RESVERATROL 4' O BETA DEXTRO (2" O GALLOYL) GLUCOPYRANOSIDE; RESVERATROL 4' O BETA DEXTRO (6" O GALLOYL) GLYUCOPYRANOSIDE; RHAPONTIGENIN O GLUCOPYRANOSIDE; RHEIN 8 O BETA GLUCOPYRANOSIDE; RHEUM OFFICINALE EXTRACT; RHEUM TANGUTICUM EXTRACT; RHUBARB EXTRACT; TRI CATECHIN; TRI O GALLOYL GLUCOPYRANOSIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; HERBACEOUS AGENT;

ANALYTIC METHOD; ARTICLE; CHEMICAL ANALYSIS; CLINICAL EVALUATION; CLUSTER ANALYSIS; COMPUTER PROGRAM; DRUG SCREENING; FRAGMENTATION REACTION; HERBAL MEDICINE; NONHUMAN; PHASE SEPARATION; PRIORITY JOURNAL; QUADRUPOLE MASS SPECTROMETRY; QUALITY CONTROL; RHEUM OFFICINALE; RHEUM TANGUTICUM; RHUBARB; SEPARATION TECHNIQUE; SPECIES DIFFERENTIATION; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; MEDICINAL PLANT; RHEUM; TIME FACTOR;

RHEUM OFFICINALE; RHEUM PALMATUM; RHEUM TANGUTICUM; RHEUM X HYBRIDUM;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; PLANT EXTRACTS; PLANTS, MEDICINAL; QUALITY CONTROL; RHEUM; TANDEM MASS SPECTROMETRY; TIME FACTORS;

EID: 84923048116     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201400971     Document Type: Article

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