RAD18 activates the G2/M checkpoint through DNA damage signaling to maintain genome integrity after ionizing radiation exposure

PLoS ONE

Volumn 10, Issue 2, 2015, Pages

  Sasatani, Megumi ^a   Xu, Yanbin ^a   Kawai, Hidehiko ^a   Cao, Lili ^a   Tateishi, Satoshi ^b   Shimura, Tsutomu ^c   Li, Jianxiang ^a   Iizuka, Daisuke ^a   Noda, Asao ^d   Hamasaki, Kanya ^d   Kusunoki, Yoichiro ^d   Kamiya, Kenji ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF PUBLIC HEALTH   (Japan)

^d RADIATION EFFECTS RESEARCH FOUNDATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

53BP1 PROTEIN; ATM PROTEIN; BINDING PROTEIN; GAMMA H2AX; HISTONE H2AX; RAD18 PROTEIN; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; HISTONE; RAD18 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CONTROLLED STUDY; DNA DAMAGE; G2 PHASE CELL CYCLE CHECKPOINT; GENOME; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; MICRONUCLEUS; MOUSE; NONHUMAN; PROTEIN DEPLETION; PROTEIN FUNCTION; RADIATION EXPOSURE; RADIOSENSITIVITY; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; GENETICS; GENOMIC INSTABILITY; KNOCKOUT MOUSE; METABOLISM; RADIATION DOSE; RADIATION RESPONSE; THYMOCYTE;

ANIMALS; APOPTOSIS; CELL LINE; DNA DAMAGE; DNA-BINDING PROTEINS; G2 PHASE CELL CYCLE CHECKPOINTS; GENOMIC INSTABILITY; HISTONES; HUMANS; MICE; MICE, KNOCKOUT; MICRONUCLEI, CHROMOSOME-DEFECTIVE; RADIATION TOLERANCE; RADIATION, IONIZING; SIGNAL TRANSDUCTION; THYMOCYTES;

EID: 84923040703     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0117845     Document Type: Article

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