Genetic evidence that relative synaptic efficacy biases the outcome of synaptic competition

Nature

Volumn 424, Issue 6947, 2003, Pages 430-434

  Buffelli, Mario ^a,b   Burgess, Robert W ^a,d   Feng, Guoping ^a,e   Lobe, Corrinne G ^c   Lichtman, Jeff W ^a   Sanes, Joshua R ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF VERONA   (Italy)

^c SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^d JACKSON LABORATORY   (United States)

^e DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUSCLE; NEUROLOGY;

MUSCLE FIBERS;

GENETIC ENGINEERING;

CHOLINE ACETYLTRANSFERASE; CHOLINERGIC RECEPTOR;

BIOLOGY; NERVOUS SYSTEM;

ANIMAL CELL; ARTICLE; BINDING COMPETITION; CELL TYPE; CONTROLLED STUDY; GENE ACTIVATION; MOTONEURON; MOUSE; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SYNAPTIC TRANSMISSION; TRANSGENIC MOUSE;

ANIMALS; AXONS; CHOLINE O-ACETYLTRANSFERASE; GENE DELETION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MODELS, NEUROLOGICAL; MOTOR NEURONS; MUSCLE, SKELETAL; NEUROMUSCULAR JUNCTION; NEURONAL PLASTICITY; SYNAPSES; SYNAPTIC TRANSMISSION; TRANSGENES;

ANIMALIA; MUS MUSCULUS; VERTEBRATA;

EID: 0042532329     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01844     Document Type: Article

References (30)

1. Katz, L. C. & Shatz, C. J. Synaptic activity and the construction of cortical circuits. Science 274, 1133-1138 (1996).
2. Sengpiel, F. & Kind, P. C. The role of activity in development of the visual system. Curr. Biol. 12, R818-R826 (2002).
3. Lichtman, J. W. & Colman, H. Synapse elimination and indelible memory. Neuron 25, 269-278 (2000).
4. Personius, K. E. & Balice-Gordon, R. J. Activity-dependent synaptic plasticity: insights from neuromuscular junctions. Neuroscientist 8, 414-422 (2002).
5. Sanes, J. R. & Lichtman, J. W. Development of the vertebrate neuromuscular junction. Annu. Rev. Neurosci. 22, 389-442 (1999).
6. Walsh, M. K. & Lichtman, J. W. In vivo time-lapse imaging of synaptic takeover associated with naturally occurring synapse elimination. Neuron 37, 67-73 (2003).
7. Benoit, P. & Changeux, J. P. Consequences of tenotomy on the evolution of multiinnervation in developing rat soleus muscle. Brain Res. 99, 354-358 (1975).
8. Thompson, W., Kuffler, D. P. & Jansen, J. K. The effect of prolonged, reversible block of nerve impulses on the elimination of polyneuronal innervation of new-born rat skeletal muscle fibers. Neuroscience 4, 271-281 (1979).
9. Ding, R., Jansen, J. K., Laing, N. G. & Tonnesen, H. The innervation of skeletal muscles in chickens curarized during early development. J. Neurocytol. 12, 887-919 (1983).
10. Thompson, W. Synapse elimination in neonatal rat muscle is sensitive to pattern of muscle use. Nature 302, 614-616 (1983).
11. Duxson, M. J. The effect of postsynaptic block on development of the neuromuscular junction in postnatal rats. J. Neurocytol. 11, 395-408 (1982).
12. O'Brien, R. A., Ostberg, A. J. & Vrbova, G. Observations on the elimination of polyneuronal innervation in developing mammalian skeletal muscle. J. Physiol. (Lond.) 282, 571-582 (1978).
13. Busetto, G., Buffelli, M., Tognana, E., Bellico, F. & Cangiano, A. Hebbian mechanisms revealed by electrical stimulation at developing rat neuromuscular junctions. J. Neurosci. 20, 685-695 (2000).
14. Barber, M. J. & Lichtman, J. W. Activity-driven synapse elimination leads paradoxically to domination by inactive neurons. J. Neurosci. 19, 9975-9985 (1999).
15. Hata, Y., Tsumoto, T. & Stryker, M. P. Selective pruning of more active afferents when cat visual cortex is pharmacologically inhibited. Neuron 22, 375-381 (1999).
16. Costanzo, E. M., Barry, J. A. & Ribchester, R. R. Competition at silent synapses in reinnervated skeletal muscle. Nature Neurosci. 3, 694-700 (2000).
17. Ridge, R. M. & Betz, W. J. The effect of selective, chronic stimulation on motor unit size in developing rat muscle. J. Neurosci. 4, 2614-2620 (1984).
18. Callaway, E. M., Soha, J. M. & Van Essen, D. C. Competition favouring inactive over active motor neurons during synapse elimination. Nature 328, 422-426 (1987).
19. Misgeld, T. et al. Roles of neurotransmitter in synapse formation: development of neuromuscular junctions lacking choline acetyltransferase. Neuron 36, 635-648 (2002).
20. Brandon, E. P., Lin, W., D'Amour, K. A., Pizzo, D. P., Dominguez, B., Sugiura, Y., Thode, S., Ko, C. P., Thai, L. I., Gage, F. H. & Lee, K. F. Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice. J. Neurosci. 23, 539-549 (2003).
21. Metzger, D. & Chambon, P. Site- and time-specific gene targeting in the mouse. Methods 24, 71-80 (2001).
22. Guo, C., Yang, W. & Lobe, C. G. A Cre recombinase transgene with mosaic, widespread tamoxifen-inducible action. Genesis 32, 8-18 (2002).
23. Feng, G. et al. Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron 28, 41-51 (2000).
24. Lewandoski, M. & Martin, G. R. Cre-mediated chromosome loss in mice. Nature Genet. 17, 223-225 (1997).
25. Kasthuri, N. & Lichtman, J. W. The role of neuronal identity in synaptic competition. Nature 424, 426-430 (2003).
26. Keller-Peck, C. R., Walsh, M. K., Gan, W. B., Feng, G., Sanes, J. R. & Lichtman, J. W. Asynchronous synapse elimination in neonatal motor units: studies using GFP transgenic mice. Neuron 31, 381-394 (2001).
27. Personius, K. E. & Balice-Gordon, R. J. Loss of correlated motor neuron activity during synaptic competition at developing neuromuscular synapses. Neuron 31, 395-408 (2001).
28. Buffelli, M., Busetto, G., Cangiano, L. & Cangiano, A. Perinatal switch from synchronous to asynchronous activity of motoneurons: link with synapse elimination. Proc. Natl Acad. Sci. USA 99, 13200-13205 (2002).
29. Lakso, M. et al. Targeted oncogene activation by site-specific recombination in transgenic mice. Proc. Natl Acad. Sci. USA 89, 6232-6236 (1992).
30. Rodriguez, C. I. et al. High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP. Nature Genet. 25, 139-140 (2000).