Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch

Nature Communications

Volumn 5, Issue , 2014, Pages

  Poole, Kate ^a   Herget, Regina ^a   Lapatsina, Liudmila ^a   Ngo, Ha Duong ^b   Lewin, Gary R ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ION CHANNEL; MESSENGER RNA; PIEZO1 ION CHANNEL; PIEZO2 ION CHANNEL; SCAFFOLD PROTEIN; STOMATIN; STOMATIN LIKE PROTEIN 3; SYNAPSIN II; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; NERVE PROTEIN; PIEZO1 PROTEIN, MOUSE; PIEZO2 PROTEIN, MOUSE; PRIMER DNA; STOML3 PROTEIN, MOUSE;

CELLS AND CELL COMPONENTS; ION; MAGNITUDE; NERVOUS SYSTEM; PHYSIOLOGY; PROTEIN; RODENT;

ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; CHANNEL GATING; CONTROLLED STUDY; DESENSITIZATION; FEMALE; FORCE TRANSDUCER; INACTIVATION TIME CONSTANT; INTRACELLULAR SIGNALING; LATENT PERIOD; LIMIT OF QUANTITATION; MALE; MECHANICAL STIMULATION; MECHANORECEPTOR; MECHANOTRANSDUCTION; MISSENSE MUTATION; MOUSE; NERVE FIBER GROWTH; NEURITE; NONHUMAN; OLIGOMERIZATION; PAIN RECEPTOR; PHENOTYPE; PIEZOELECTRICITY; PROTEIN FUNCTION; PROTEIN POLYMORPHISM; PROTEIN STRUCTURE; QUANTITATIVE ANALYSIS; QUANTITATIVE STUDY; SENSORY NERVE CELL; SKIN SENSATION; STIMULUS RESPONSE; ANIMAL; BIOLOGICAL MODEL; BIOPHYSICS; C57BL MOUSE; CYTOLOGY; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOBLOTTING; IMMUNOPRECIPITATION; KNOCKOUT MOUSE; METABOLISM; NONPARAMETRIC TEST; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; SPINAL GANGLION; STIMULATION;

MAMMALIA; MUS;

ANIMALS; BIOPHYSICS; DNA PRIMERS; GANGLIA, SPINAL; HEK293 CELLS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; ION CHANNELS; MECHANOTRANSDUCTION, CELLULAR; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, SCANNING; MODELS, NEUROLOGICAL; NERVE TISSUE PROTEINS; PATCH-CLAMP TECHNIQUES; PHYSICAL STIMULATION; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SENSORY RECEPTOR CELLS; STATISTICS, NONPARAMETRIC;

EID: 84902599773     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4520     Document Type: Article

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