Human PrimPol mutation associated with high myopia has a DNA replication defect

Nucleic Acids Research

Volumn 42, Issue 19, 2014, Pages 12102-12111

  Keen, Benjamin A ^a   Bailey, Laura J ^a   Jozwiakowski, Stanislaw K ^a   Doherty, Aidan J ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; DNA PRIMASE; DOUBLE STRANDED DNA; SINGLE STRANDED DNA; DNA; DNA DIRECTED DNA POLYMERASE; MULTIFUNCTIONAL ENZYME; PRIMPOL PROTEIN, HUMAN;

ALPHA HELIX; ANIMAL CELL; ARTICLE; BETA SHEET; BINDING AFFINITY; BIRD; CATALYTIC EFFICIENCY; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DNA BINDING; DNA DAMAGE; DNA REPLICATION; ENZYME ACTIVITY; ENZYME STABILITY; GENETIC ASSOCIATION; HIGH MYOPIA; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PATHOGENESIS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MYOPIA;

DNA; DNA PRIMASE; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; HUMANS; MULTIFUNCTIONAL ENZYMES; MYOPIA; POINT MUTATION;

EID: 84922999089     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku879     Document Type: Article

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