메뉴 건너뛰기




Volumn 8, Issue 1, 2015, Pages 579-588

Ghrelin inhibits angii-induced expression of TNF-α, IL-8, MCP-1 in human umbilical vein endothelial cells

Author keywords

Atherosclerosis; Ghrelin; Inflammation; Interleukin 8; Monocyte chemoattractant protein 1; NF B and MAPK pathways; Tumor necrosis factor

Indexed keywords

ANGIOTENSIN II; GHRELIN; GHRELIN RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

EID: 84922987721     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (31)

References (39)
  • 1
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999; 402: 656-60.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 3
    • 0034741715 scopus 로고    scopus 로고
    • [125I-His (9)]-ghrelin, a novel radioligand for localizing GHS orphan receptors in human and rat tissue: Up-regulation of receptors with atherosclerosis
    • Katugampola SD, Pallikaros Z, Davenport AP. [125I-His (9)]-ghrelin, a novel radioligand for localizing GHS orphan receptors in human and rat tissue: up-regulation of receptors with atherosclerosis. Br J Pharmacol 2001; 134: 143-9.
    • (2001) Br J Pharmacol , vol.134 , pp. 143-149
    • Katugampola, S.D.1    Pallikaros, Z.2    Davenport, A.P.3
  • 4
    • 84859591097 scopus 로고    scopus 로고
    • Plasma ghrelin levels are closely associated with severity and morphology of angiographically-detected coronary atherosclerosis in Chinese patients with diabetes mellitus
    • Zhang M, Fang WY, Yuan F, Qu XK, Liu H, Xu YJ, Chen H, Yu YF, Shen Y, Zheng ZC. Plasma ghrelin levels are closely associated with severity and morphology of angiographically-detected coronary atherosclerosis in Chinese patients with diabetes mellitus. Acta Pharmacol Sin 2012; 33: 452-8.
    • (2012) Acta Pharmacol Sin , vol.33 , pp. 452-458
    • Zhang, M.1    Fang, W.Y.2    Yuan, F.3    Qu, X.K.4    Liu, H.5    Xu, Y.J.6    Chen, H.7    Yu, Y.F.8    Shen, Y.9    Zheng, Z.C.10
  • 7
    • 71049136556 scopus 로고    scopus 로고
    • Plasma ghrelin levels are associated with coronary microvascular and endothelial dysfunction in peritoneal dialysis patients
    • Caliskan Y, Gorgulu N, Yelken B, Yazici H, Oflaz H, Elitok A, Turkmen A, Bozfakioglu S, Sever MS. Plasma ghrelin levels are associated with coronary microvascular and endothelial dysfunction in peritoneal dialysis patients. Ren Fail 2009; 31: 807-13.
    • (2009) Ren Fail , vol.31 , pp. 807-813
    • Caliskan, Y.1    Gorgulu, N.2    Yelken, B.3    Yazici, H.4    Oflaz, H.5    Elitok, A.6    Turkmen, A.7    Bozfakioglu, S.8    Sever, M.S.9
  • 8
    • 70449433040 scopus 로고    scopus 로고
    • A concerted kinase interplay identifies PPARgamma as a molecular target of ghrelin signaling in macrophages
    • Demers A, Caron V, Rodrigue-Way A, Wahli W, Ong H, Tremblay A. A concerted kinase interplay identifies PPARgamma as a molecular target of ghrelin signaling in macrophages. PLoS One 2009; 4: e7728.
    • (2009) Plos One , vol.4
    • Demers, A.1    Caron, V.2    Rodrigue-Way, A.3    Wahli, W.4    Ong, H.5    Tremblay, A.6
  • 9
    • 54749146658 scopus 로고    scopus 로고
    • Inhibition of proliferation and apoptosis of vascular smooth muscle cells by ghrelin
    • Zhang M, Yuan F, Liu H, Chen H, Qiu X, Fang W. Inhibition of proliferation and apoptosis of vascular smooth muscle cells by ghrelin. Acta Biochim Biophys Sin 2008; 40:769-76.
    • (2008) Acta Biochim Biophys Sin , vol.40 , pp. 769-776
    • Zhang, M.1    Yuan, F.2    Liu, H.3    Chen, H.4    Qiu, X.5    Fang, W.6
  • 11
    • 37249065175 scopus 로고    scopus 로고
    • Effect of exogenous ghrelin on cell differentiation antigen 40 expression in endothelial cells
    • Zhang M, Yuan F, Chen H, Qiu X, Fang W. Effect of exogenous ghrelin on cell differentiation antigen 40 expression in endothelial cells. Acta Biochim Biophys Sin 2007; 39: 974-81.
    • (2007) Acta Biochim Biophys Sin , vol.39 , pp. 974-981
    • Zhang, M.1    Yuan, F.2    Chen, H.3    Qiu, X.4    Fang, W.5
  • 12
    • 33644668189 scopus 로고    scopus 로고
    • Pathophysiological levels of the obesity related peptides resistin and ghrelin increase adhesion molecule expression on human vascular endothelial cells
    • Skilton MR, Nakhla S, Sieveking DP, Caterson ID, Celermajer DS. Pathophysiological levels of the obesity related peptides resistin and ghrelin increase adhesion molecule expression on human vascular endothelial cells. Clin Exp Pharmacol Physiol 2005; 32: 839-44.
    • (2005) Clin Exp Pharmacol Physiol , vol.32 , pp. 839-844
    • Skilton, M.R.1    Nakhla, S.2    Sieveking, D.P.3    Caterson, I.D.4    Celermajer, D.S.5
  • 15
    • 42649100351 scopus 로고    scopus 로고
    • Upregulation of interleukin-8/CXCL8 in vascular smooth muscle cells from spontaneously hypertensive rats
    • Kim HY, Kang YJ, Song IH, Choi HC, Kim HS. Upregulation of interleukin-8/CXCL8 in vascular smooth muscle cells from spontaneously hypertensive rats. Hypertens Res 2008; 31: 515-23.
    • (2008) Hypertens Res , vol.31 , pp. 515-523
    • Kim, H.Y.1    Kang, Y.J.2    Song, I.H.3    Choi, H.C.4    Kim, H.S.5
  • 16
    • 84922976810 scopus 로고    scopus 로고
    • The effect of activation peroxidase proliferation activated receptor on AngⅡinduced expression of monocyte chemoattractant protein-1 in Human Umbilical Vein Endothelial Cells
    • Li CH, Zhang XC. The effect of activation peroxidase proliferation activated receptor on AngⅡinduced expression of monocyte chemoattractant protein-1 in Human Umbilical Vein Endothelial Cells. Chinese Journal of Geriatrics 2006; 25: 664-7.
    • (2006) Chinese Journal of Geriatrics , vol.25 , pp. 664-667
    • Li, C.H.1    Zhang, X.C.2
  • 17
    • 77953236516 scopus 로고    scopus 로고
    • Role of AT2 receptors on angiotensin II-induced tumor necrosis factor alpha and interleukin 1 beta secretion in adult rat cardiac fibroblasts
    • Jiang XY, Gao GD, Zhou J, Guo R, Li YX. Role of AT2 receptors on angiotensin II-induced tumor necrosis factor alpha and interleukin 1 beta secretion in adult rat cardiac fibroblasts. Nan Fang Yi Ke Da Xue Xue Bao 2007; 27: 1307-9.
    • (2007) Nan Fang Yi Ke Da Xue Xue Bao , vol.27 , pp. 1307-1309
    • Jiang, X.Y.1    Gao, G.D.2    Zhou, J.3    Guo, R.4    Li, Y.X.5
  • 18
    • 0025137467 scopus 로고
    • An improvement of the single-step method of RNA isolation by ac-id guanidinium thiocyanate-phenol-chloroform extraction
    • Puissant C, Houdebine LM. An improvement of the single-step method of RNA isolation by ac-id guanidinium thiocyanate-phenol-chloroform extraction. Biotechniques 1990; 8: 148-9.
    • (1990) Biotechniques , vol.8 , pp. 148-149
    • Puissant, C.1    Houdebine, L.M.2
  • 19
    • 0032791611 scopus 로고    scopus 로고
    • Cytokine-inducible CD40 gene expression in vascular smooth muscle cells is mediated by nuclear factor kappa B and signal transducer and activation of transcription-1
    • Krzesz R, Wagner AH, Cattaruzza M, Hecker M. Cytokine-inducible CD40 gene expression in vascular smooth muscle cells is mediated by nuclear factor kappa B and signal transducer and activation of transcription-1. FEBS Lett 1999; 453: 191-6.
    • (1999) FEBS Lett , vol.453 , pp. 191-196
    • Krzesz, R.1    Wagner, A.H.2    Cattaruzza, M.3    Hecker, M.4
  • 20
    • 33646723047 scopus 로고    scopus 로고
    • Nuclear factor-kB signaling pathway constitutively activated in esophageal squamous cell carcinoma cell lines and inhibition of growth of cells by small interfering RNA
    • Tian F, Zang WD, Hou WH, Liu HT, Xue LX. Nuclear factor-kB signaling pathway constitutively activated in esophageal squamous cell carcinoma cell lines and inhibition of growth of cells by small interfering RNA. Acta Biochim Biophys Sin 2006; 38: 318-26.
    • (2006) Acta Biochim Biophys Sin , vol.38 , pp. 318-326
    • Tian, F.1    Zang, W.D.2    Hou, W.H.3    Liu, H.T.4    Xue, L.X.5
  • 22
    • 84878619468 scopus 로고    scopus 로고
    • Administration of ghrelin improves inflammation, oxidative stress, and apoptosis during and after non-alcoholic fatty liver disease development
    • Li Y, Hai J, Li L, Chen X, Peng H, Cao M, Zhang Q. Administration of ghrelin improves inflammation, oxidative stress, and apoptosis during and after non-alcoholic fatty liver disease development. Endocrine 2013; 43: 376-86.
    • (2013) Endocrine , vol.43 , pp. 376-386
    • Li, Y.1    Hai, J.2    Li, L.3    Chen, X.4    Peng, H.5    Cao, M.6    Zhang, Q.7
  • 25
    • 0037384111 scopus 로고    scopus 로고
    • Ghrelin improves left ventricular dysfunction and cardiac cachexia in heart failure
    • Nagaya N, Kanqawa K. Ghrelin improves left ventricular dysfunction and cardiac cachexia in heart failure. Curr Opin Pharmacol 2003; 3: 146-51.
    • (2003) Curr Opin Pharmacol , vol.3 , pp. 146-151
    • Nagaya, N.1    Kanqawa, K.2
  • 27
    • 0036528824 scopus 로고    scopus 로고
    • Monocytes/macrophages in hypertension
    • Hilgers KF. Monocytes/macrophages in hypertension. J Hypertens 2002; 20: 593-6.
    • (2002) J Hypertens , vol.20 , pp. 593-596
    • Hilgers, K.F.1
  • 28
    • 0036120305 scopus 로고    scopus 로고
    • Pleiotropic effects of chemokines in vascular lesion development
    • Gerszten RE. Pleiotropic effects of chemokines in vascular lesion development. Artherioscler Thromb Vasc Biol 2002; 22: 528-9.
    • (2002) Artherioscler Thromb Vasc Biol , vol.22 , pp. 528-529
    • Gerszten, R.E.1
  • 29
    • 0037022910 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis
    • Libby P, Mra AM. Inflammation and atherosclerosis. Circulation 105: 1135-43.
    • Circulation , vol.105 , pp. 1135-1143
    • Libby, P.1    Mra, A.M.2
  • 32
    • 0036687932 scopus 로고    scopus 로고
    • Comparison of vasodilators in human internal mammary artery: Ghrelin is a potent physiological antagonist of endothelin-1
    • Wiley KE, Davenport AP. Comparison of vasodilators in human internal mammary artery: ghrelin is a potent physiological antagonist of endothelin-1. Br J Pharmacol 2002; 136: 1146-52.
    • (2002) Br J Pharmacol , vol.136 , pp. 1146-1152
    • Wiley, K.E.1    Davenport, A.P.2
  • 34
    • 33645069631 scopus 로고    scopus 로고
    • Thera-peutic action of ghrelin in a mouse model of colitis
    • Gonzalez-Rey E, Chorny A, Delgado M. Thera-peutic action of ghrelin in a mouse model of colitis. Gastroenterology 2006; 130: 1707-20.
    • (2006) Gastroenterology , vol.130 , pp. 1707-1720
    • Gonzalez-Rey, E.1    Chorny, A.2    Delgado, M.3
  • 36
    • 42649100351 scopus 로고    scopus 로고
    • Upregulation of Interleukin-8/CXCL8 in Va-scular Smooth Muscle Cells from Sponta-neously Hypertensive Rats
    • Kim YI, Kang YJ, Song IH, Choi HC, Kim HS. Upregulation of Interleukin-8/CXCL8 in Va-scular Smooth Muscle Cells from Sponta-neously Hypertensive Rats. Hypertens Res 2008; 31: 515-23.
    • (2008) Hypertens Res , vol.31 , pp. 515-523
    • Kim, Y.I.1    Kang, Y.J.2    Song, I.H.3    Choi, H.C.4    Kim, H.S.5
  • 37
    • 4444289166 scopus 로고    scopus 로고
    • Ghrelin enhances the growth of cultured human adrenal zona glomerulosa cells by exerting MAPK-mediated proliferogenic and antiapoptotic effects
    • Mazzocchi G, Neri G, Rucinski M, Rebuffat P, Spinazzi R, Malendowicz LK, Nussdorfer GG. Ghrelin enhances the growth of cultured human adrenal zona glomerulosa cells by exerting MAPK-mediated proliferogenic and antiapoptotic effects. Peptides 2004; 25: 1269-77.
    • (2004) Peptides , vol.25 , pp. 1269-1277
    • Mazzocchi, G.1    Neri, G.2    Rucinski, M.3    Rebuffat, P.4    Spinazzi, R.5    Malendowicz, L.K.6    Nussdorfer, G.G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.