A novel conditional platelet depletion mouse model reveals the importance of platelets in protection against staphylococcus aureus bacteremia

Journal of Thrombosis and Haemostasis

Volumn 13, Issue 2, 2015, Pages 303-313

  Wuescher, L M ^a   Takashima, A ^a   Worth, R G ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

Bacteria; Blood platelets; Sepsis; Septic shock; Staphylococcus aureus

Indexed keywords

CRE RECOMBINASE; CYTOKINE; DIPHTHERIA TOXIN; RECEPTOR; SIMIAN DIPHTHERIA TOXIN RECEPTOR; THROMBOCYTE FACTOR 4; UNCLASSIFIED DRUG; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; INTEGRASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL LOAD; BLOOD CELL; BLOODSTREAM INFECTION; CONTROLLED STUDY; EXPERIMENTAL MODEL; FEMALE; KIDNEY INJURY; MALE; MEGAKARYOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEPTIC SHOCK; STAPHYLOCOCCAL BACTEREMIA; THROMBOCYTE; THROMBOCYTE COUNT; AGONISTS; ANIMAL; BACTEREMIA; BLOOD; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; KIDNEY; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TIME FACTOR; TRANSGENIC MOUSE;

ANIMALS; BACTEREMIA; BACTERIAL LOAD; BLOOD PLATELETS; CYTOKINES; DIPHTHERIA TOXIN; DISEASE MODELS, ANIMAL; FEMALE; HEPARIN-BINDING EGF-LIKE GROWTH FACTOR; HOST-PATHOGEN INTERACTIONS; INTEGRASES; KIDNEY; MALE; MICE, INBRED C57BL; MICE, TRANSGENIC; PLATELET COUNT; PLATELET FACTOR 4; SHOCK, SEPTIC; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TIME FACTORS;

EID: 84922953786     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/jth.12795     Document Type: Article

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