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Volumn 9, Issue 1-2, 2015, Pages 64-71

Biomarkers of colorectal cancer: Recent advances and future challenges

Author keywords

Biomarker; Colorectal cancer; Diagnosis; Immunohistochemistry; Predictive; Prognosis

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 1; ANNEXIN; BIOLOGICAL MARKER; CARCINOEMBRYONIC ANTIGEN; CYTOCHROME P450; DASATINIB; IMATINIB; MATRIX METALLOPROTEINASE; PANITUMUMAB; PROTEOME; TUMOR MARKER; TUMOR PROTEIN;

EID: 84922948849     PISSN: 18628346     EISSN: 18628354     Source Type: Journal    
DOI: 10.1002/prca.201400082     Document Type: Review
Times cited : (52)

References (60)
  • 1
    • 78049485263 scopus 로고    scopus 로고
    • Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
    • Ferlay, J., Shin, H. R., Bray, F., Forman, D. et al., Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int. J. Cancer 2010, 127, 2893-2917.
    • (2010) Int. J. Cancer , vol.127 , pp. 2893-2917
    • Ferlay, J.1    Shin, H.R.2    Bray, F.3    Forman, D.4
  • 3
    • 44949242293 scopus 로고    scopus 로고
    • Cochrane systematic review of colorectal cancer screening using the fecal occult blood test (hemoccult): an update
    • Hewitson, P., Glasziou, P., Watson, E., Towler, B., Irwig, L., Cochrane systematic review of colorectal cancer screening using the fecal occult blood test (hemoccult): an update. Am. J. Gastroenterol. 2008, 103, 1541-1549.
    • (2008) Am. J. Gastroenterol. , vol.103 , pp. 1541-1549
    • Hewitson, P.1    Glasziou, P.2    Watson, E.3    Towler, B.4    Irwig, L.5
  • 4
    • 84871666335 scopus 로고    scopus 로고
    • Effect of flexible sigmoidoscopy-based screening on incidence and mortality of colorectal cancer: a systematic review and meta-analysis of randomized controlled trials
    • Elmunzer, B. J., Hayward, R. A., Schoenfeld, P. S., Saini, S. D. et al., Effect of flexible sigmoidoscopy-based screening on incidence and mortality of colorectal cancer: a systematic review and meta-analysis of randomized controlled trials. PLoS Med. 2012, 9, e1001352.
    • (2012) PLoS Med. , vol.9 , pp. e1001352
    • Elmunzer, B.J.1    Hayward, R.A.2    Schoenfeld, P.S.3    Saini, S.D.4
  • 5
    • 84899628178 scopus 로고    scopus 로고
    • Colorectal cancer
    • Brenner, H., Kloor, M., Pox, C. P., Colorectal cancer. Lancet 2014, 383, 1490-1502.
    • (2014) Lancet , vol.383 , pp. 1490-1502
    • Brenner, H.1    Kloor, M.2    Pox, C.P.3
  • 6
    • 84881259506 scopus 로고    scopus 로고
    • Progress in the identification of plasma biomarkers of colorectal cancer
    • Coghlin, C., Murray, G. I., Progress in the identification of plasma biomarkers of colorectal cancer. Proteomics 2013, 13, 2227-2228.
    • (2013) Proteomics , vol.13 , pp. 2227-2228
    • Coghlin, C.1    Murray, G.I.2
  • 7
    • 84872742367 scopus 로고    scopus 로고
    • Developing proteomics-based biomarkers for colorectal neoplasms for clinical practice: opportunities and challenges
    • Luo, Y., Wang, L., Wang, J., Developing proteomics-based biomarkers for colorectal neoplasms for clinical practice: opportunities and challenges. Proteomics Clin. Appl. 2013, 7, 30-41.
    • (2013) Proteomics Clin. Appl. , vol.7 , pp. 30-41
    • Luo, Y.1    Wang, L.2    Wang, J.3
  • 9
    • 84881233089 scopus 로고    scopus 로고
    • Following the protein biomarker trail to colorectal cancer
    • Coghlin, C., Murray, G. I., Following the protein biomarker trail to colorectal cancer. Colorectal Cancer 2012, 1, 93-96.
    • (2012) Colorectal Cancer , vol.1 , pp. 93-96
    • Coghlin, C.1    Murray, G.I.2
  • 10
    • 0037371192 scopus 로고    scopus 로고
    • CDX2, a highly sensitive and specific marker of adenocarcinomas of intestinal origin: an immunohistochemical survey of 476 primary and metastatic carcinomas
    • Werling, R. W., Yaziji, H., Bacchi, C. E., Gown, A. M., CDX2, a highly sensitive and specific marker of adenocarcinomas of intestinal origin: an immunohistochemical survey of 476 primary and metastatic carcinomas. Am. J. Surg. Pathol. 2003, 27, 303-310.
    • (2003) Am. J. Surg. Pathol. , vol.27 , pp. 303-310
    • Werling, R.W.1    Yaziji, H.2    Bacchi, C.E.3    Gown, A.M.4
  • 11
    • 84881259783 scopus 로고    scopus 로고
    • Proteomics in colorectal cancer translational research: biomarker discovery for clinical applications
    • de Wit, M., Fijneman, R. J., Verheul, H. M., Meijer, G. A., Jimenez, C. R., Proteomics in colorectal cancer translational research: biomarker discovery for clinical applications. Clin. Biochem. 2013, 46, 466-479.
    • (2013) Clin. Biochem. , vol.46 , pp. 466-479
    • de Wit, M.1    Fijneman, R.J.2    Verheul, H.M.3    Meijer, G.A.4    Jimenez, C.R.5
  • 12
    • 84880705235 scopus 로고    scopus 로고
    • Identification of kininogen-1 as a serum biomarker for the early detection of advanced colorectal adenoma and colorectal cancer
    • Wang, J., Wang, X., Lin, S., Chen, C. et al., Identification of kininogen-1 as a serum biomarker for the early detection of advanced colorectal adenoma and colorectal cancer. PLoS One 2013, 8, e70519.
    • (2013) PLoS One , vol.8 , pp. e70519
    • Wang, J.1    Wang, X.2    Lin, S.3    Chen, C.4
  • 13
    • 45549091249 scopus 로고    scopus 로고
    • Plasma glycoprotein profiling for colorectal cancer biomarker identification by lectinglycoarray and lectin blot
    • Qiu, Y., Patwa, T. H., Xu, L., Shedden, K. et al., Plasma glycoprotein profiling for colorectal cancer biomarker identification by lectinglycoarray and lectin blot. J. Proteome Res. 2008, 7, 1693-1703.
    • (2008) J. Proteome Res. , vol.7 , pp. 1693-1703
    • Qiu, Y.1    Patwa, T.H.2    Xu, L.3    Shedden, K.4
  • 14
    • 0025239826 scopus 로고
    • Studies on components of the contact phase system in patients with advanced gastrointestinal cancer
    • Roeise, O., Sivertsen, S., Ruud, T. E., Bouma, B. N. et al., Studies on components of the contact phase system in patients with advanced gastrointestinal cancer. Cancer 1990, 65, 1355-1359.
    • (1990) Cancer , vol.65 , pp. 1355-1359
    • Roeise, O.1    Sivertsen, S.2    Ruud, T.E.3    Bouma, B.N.4
  • 15
    • 84899462458 scopus 로고    scopus 로고
    • Biomarkers of coordinate metabolic reprogramming in colorectal tumors in mice and humans
    • Manna, S. K., Tanaka, N., Krausz, K. W., Haznadar, M. et al., Biomarkers of coordinate metabolic reprogramming in colorectal tumors in mice and humans. Gastroenterology 2014, 146, 1313-1324.
    • (2014) Gastroenterology , vol.146 , pp. 1313-1324
    • Manna, S.K.1    Tanaka, N.2    Krausz, K.W.3    Haznadar, M.4
  • 16
    • 42649141934 scopus 로고    scopus 로고
    • Metachronous cancer development in patients with sporadic colorectal adenomas-multivariate risk model with independent and combined value of hTERT and survivin
    • Soreide, K., Gudlaugsson, E., Skaland, I., Janssen, E. A. et al., Metachronous cancer development in patients with sporadic colorectal adenomas-multivariate risk model with independent and combined value of hTERT and survivin. Int. J. Colorectal Dis. 2008, 23, 389-400.
    • (2008) Int. J. Colorectal Dis. , vol.23 , pp. 389-400
    • Soreide, K.1    Gudlaugsson, E.2    Skaland, I.3    Janssen, E.A.4
  • 17
    • 30744442279 scopus 로고    scopus 로고
    • Cancer: the matrix is now in control
    • Comoglio, P. M., Trusolino, L., Cancer: the matrix is now in control. Nat. Med. 2005, 11, 1156-1159.
    • (2005) Nat. Med. , vol.11 , pp. 1156-1159
    • Comoglio, P.M.1    Trusolino, L.2
  • 18
  • 19
    • 77955497101 scopus 로고    scopus 로고
    • Current and emerging concepts in tumour metastasis
    • Coghlin, C., Murray, G. I., Current and emerging concepts in tumour metastasis. J. Pathol. 2010, 222, 1-15.
    • (2010) J. Pathol. , vol.222 , pp. 1-15
    • Coghlin, C.1    Murray, G.I.2
  • 20
    • 84899809569 scopus 로고    scopus 로고
    • The role of gene regulatory networks in promoting cancer progression and metastasis
    • Coghlin, C., Murray, G. I., The role of gene regulatory networks in promoting cancer progression and metastasis. Future Oncol. 2014, 10, 735-748.
    • (2014) Future Oncol. , vol.10 , pp. 735-748
    • Coghlin, C.1    Murray, G.I.2
  • 21
    • 84868515495 scopus 로고    scopus 로고
    • ColoGuidePro: a prognostic 7-gene expression signature for stage III colorectal cancer patients
    • Sveen, A., Agesen, T. H., Nesbakken, A., Meling, G. I. et al., ColoGuidePro: a prognostic 7-gene expression signature for stage III colorectal cancer patients. Clin. Cancer Res. 2012, 18, 6001-6010.
    • (2012) Clin. Cancer Res. , vol.18 , pp. 6001-6010
    • Sveen, A.1    Agesen, T.H.2    Nesbakken, A.3    Meling, G.I.4
  • 22
    • 79951506562 scopus 로고    scopus 로고
    • Gene expression signature to improve prognosis prediction of stage II and III colorectal cancer
    • Salazar, R., Roepman, P., Capella, G., Moreno, V. et al., Gene expression signature to improve prognosis prediction of stage II and III colorectal cancer. J. Clin. Oncol. 2011, 29, 17-24.
    • (2011) J. Clin. Oncol. , vol.29 , pp. 17-24
    • Salazar, R.1    Roepman, P.2    Capella, G.3    Moreno, V.4
  • 23
    • 84879114673 scopus 로고    scopus 로고
    • Independent validation of a prognostic genomic signature (ColoPrint) for patients with stage II colon cancer
    • Maak, M., Simon, I., Nitsche, U., Roepman, P. et al., Independent validation of a prognostic genomic signature (ColoPrint) for patients with stage II colon cancer. Ann. Surg. 2013, 257, 1053-1058.
    • (2013) Ann. Surg. , vol.257 , pp. 1053-1058
    • Maak, M.1    Simon, I.2    Nitsche, U.3    Roepman, P.4
  • 24
    • 77956103532 scopus 로고    scopus 로고
    • A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy
    • Deschoolmeester, V., Baay, M., Specenier, P., Lardon, F., Vermorken, J. B., A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy. Oncologist 2010, 15, 699-731.
    • (2010) Oncologist , vol.15 , pp. 699-731
    • Deschoolmeester, V.1    Baay, M.2    Specenier, P.3    Lardon, F.4    Vermorken, J.B.5
  • 25
    • 33750532981 scopus 로고    scopus 로고
    • Characterization and over-expression of chaperonin t-complex proteins in colorectal cancer
    • Coghlin, C., Carpenter, B., Dundas, S. R., Lawrie, L. C. et al., Characterization and over-expression of chaperonin t-complex proteins in colorectal cancer. J. Pathol. 2006, 210, 351-357.
    • (2006) J. Pathol. , vol.210 , pp. 351-357
    • Coghlin, C.1    Carpenter, B.2    Dundas, S.R.3    Lawrie, L.C.4
  • 26
    • 0029952713 scopus 로고    scopus 로고
    • Matrix metalloproteinase-1 is associated with poor prognosis in colorectal cancer
    • Murray, G. I., Duncan, M. E., O'Neil, P., Melvin, W. T., Fothergill, J. E., Matrix metalloproteinase-1 is associated with poor prognosis in colorectal cancer. Nat. Med. 1996, 2, 461-462.
    • (1996) Nat. Med. , vol.2 , pp. 461-462
    • Murray, G.I.1    Duncan, M.E.2    O'Neil, P.3    Melvin, W.T.4    Fothergill, J.E.5
  • 27
    • 18844370604 scopus 로고    scopus 로고
    • Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis
    • Kumarakulasingham, M., Rooney, P. H., Dundas, S. R., Telfer, C. et al., Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis. Clin. Cancer Res. 2005, 11, 3758-3765.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 3758-3765
    • Kumarakulasingham, M.1    Rooney, P.H.2    Dundas, S.R.3    Telfer, C.4
  • 28
    • 11144223556 scopus 로고    scopus 로고
    • Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers
    • Curran, S., Dundas, S. R., Buxton, J., Leeman, M. F. et al., Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers. Clin. Cancer Res. 2004, 10, 8229-8234.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 8229-8234
    • Curran, S.1    Dundas, S.R.2    Buxton, J.3    Leeman, M.F.4
  • 29
    • 81355142723 scopus 로고    scopus 로고
    • The proteomics of colorectal cancer: identification of a protein signature associated with prognosis
    • O'Dwyer, D., Ralton, L. D., O'Shea, A., Murray, G. I., The proteomics of colorectal cancer: identification of a protein signature associated with prognosis. PLoS One 2011, 6, e27718.
    • (2011) PLoS One , vol.6 , pp. e27718
    • O'Dwyer, D.1    Ralton, L.D.2    O'Shea, A.3    Murray, G.I.4
  • 30
    • 38549174826 scopus 로고    scopus 로고
    • Characterisation and protein expression profiling of annexins in colorectal cancer
    • Duncan, R., Carpenter, B., Main, L. C., Telfer, C., Murray, G. I., Characterisation and protein expression profiling of annexins in colorectal cancer. Br. J. Cancer 2008, 98, 426-433.
    • (2008) Br. J. Cancer , vol.98 , pp. 426-433
    • Duncan, R.1    Carpenter, B.2    Main, L.C.3    Telfer, C.4    Murray, G.I.5
  • 31
    • 84867338345 scopus 로고    scopus 로고
    • New prognosis biomarkers identified by dynamic proteomic analysis of colorectal cancer
    • Peng, Y., Li, X., Wu, M., Yang, J. et al., New prognosis biomarkers identified by dynamic proteomic analysis of colorectal cancer. Mol. Biosyst. 2012, 8, 3077-3088.
    • (2012) Mol. Biosyst. , vol.8 , pp. 3077-3088
    • Peng, Y.1    Li, X.2    Wu, M.3    Yang, J.4
  • 32
    • 83055168484 scopus 로고    scopus 로고
    • A quantitative proteomic approach of the different stages of colorectal cancer establishes OLFM4 as a new nonmetastatic tumor marker
    • M111009712
    • Besson, D., Pavageau, A. H., Valo, I., Bourreau, A. et al., A quantitative proteomic approach of the different stages of colorectal cancer establishes OLFM4 as a new nonmetastatic tumor marker. Mol. Cell. Proteomics 2011, 10, M111.009712.
    • (2011) Mol. Cell. Proteomics , vol.10
    • Besson, D.1    Pavageau, A.H.2    Valo, I.3    Bourreau, A.4
  • 33
    • 84871194355 scopus 로고    scopus 로고
    • Tissue-based proteomics reveals FXYD3, S100A11 and GSTM3 as novel markers for regional lymph node metastasis in colon cancer
    • Meding, S., Balluff, B., Elsner, M., Schone, C. et al., Tissue-based proteomics reveals FXYD3, S100A11 and GSTM3 as novel markers for regional lymph node metastasis in colon cancer. J. Pathol. 2012, 228, 459-470.
    • (2012) J. Pathol. , vol.228 , pp. 459-470
    • Meding, S.1    Balluff, B.2    Elsner, M.3    Schone, C.4
  • 34
    • 84908325134 scopus 로고    scopus 로고
    • Quantitative proteome profiling of lymph node-positive vs. -negative colorectal carcinomas pinpoints MX1 as a marker for lymph node metastasis
    • Croner, R. S., Sturzl, M., Rau, T. T., Metodieva, G. et al., Quantitative proteome profiling of lymph node-positive vs. -negative colorectal carcinomas pinpoints MX1 as a marker for lymph node metastasis. Int. J. Cancer 2014, 135, 2878-2886
    • (2014) Int. J. Cancer , vol.135 , pp. 2878-2886
    • Croner, R.S.1    Sturzl, M.2    Rau, T.T.3    Metodieva, G.4
  • 35
    • 80054018665 scopus 로고    scopus 로고
    • Proteomic comparison of colorectal tumours and nonneoplastic mucosa from paired patient samples using iTRAQ mass spectrometry
    • Jankova, L., Chan, C., Fung, C. L., Song, X. et al., Proteomic comparison of colorectal tumours and nonneoplastic mucosa from paired patient samples using iTRAQ mass spectrometry. Mol. Biosyst. 2011, 7, 2997-3005.
    • (2011) Mol. Biosyst. , vol.7 , pp. 2997-3005
    • Jankova, L.1    Chan, C.2    Fung, C.L.3    Song, X.4
  • 36
    • 84855942921 scopus 로고    scopus 로고
    • Clinicopathological correlates and prognostic significance of glutathione S-transferase Pi expression in 468 patients after potentially curative resection of node-positive colonic cancer
    • Tan, K. L., Jankova, L., Chan, C., Fung, C. L. et al., Clinicopathological correlates and prognostic significance of glutathione S-transferase Pi expression in 468 patients after potentially curative resection of node-positive colonic cancer. Histopathology 2011, 59, 1057-1070.
    • (2011) Histopathology , vol.59 , pp. 1057-1070
    • Tan, K.L.1    Jankova, L.2    Chan, C.3    Fung, C.L.4
  • 37
    • 84861437627 scopus 로고    scopus 로고
    • Glutathione S-transferase Pi expression predicts response to adjuvant chemotherapy for stage C colon cancer: a matched historical control study
    • 196-2407-12-196
    • Jankova, L., Robertson, G., Chan, C., Tan, K. L. et al., Glutathione S-transferase Pi expression predicts response to adjuvant chemotherapy for stage C colon cancer: a matched historical control study. BMC Cancer 2012, 12, 196-2407-12-196.
    • (2012) BMC Cancer , vol.12
    • Jankova, L.1    Robertson, G.2    Chan, C.3    Tan, K.L.4
  • 38
    • 84903256473 scopus 로고    scopus 로고
    • Tests and investigations for colorectal cancer screening
    • Carroll, M., Seaman, H., Halloran, S., Tests and investigations for colorectal cancer screening. Clin. Biochem. 2014, 47, 921-939.
    • (2014) Clin. Biochem. , vol.47 , pp. 921-939
    • Carroll, M.1    Seaman, H.2    Halloran, S.3
  • 39
    • 84871839460 scopus 로고    scopus 로고
    • The price of autonomy: should we offer individuals a choice of colorectal cancer screening strategies?
    • van Dam, L., Kuipers, E. J., Steyerberg, E. W., van Leerdam, M. E., de Beaufort, I. D., The price of autonomy: should we offer individuals a choice of colorectal cancer screening strategies? Lancet Oncol. 2013, 14, e38-e46.
    • (2013) Lancet Oncol. , vol.14 , pp. e38-e46
    • van Dam, L.1    Kuipers, E.J.2    Steyerberg, E.W.3    van Leerdam, M.E.4    de Beaufort, I.D.5
  • 40
  • 41
    • 79957458567 scopus 로고    scopus 로고
    • Cell-free nucleic acids as biomarkers in cancer patients
    • Schwarzenbach, H., Hoon, D. S., Pantel, K., Cell-free nucleic acids as biomarkers in cancer patients. Nat. Rev. Cancer. 2011, 11, 426-437.
    • (2011) Nat. Rev. Cancer. , vol.11 , pp. 426-437
    • Schwarzenbach, H.1    Hoon, D.S.2    Pantel, K.3
  • 42
    • 84879543880 scopus 로고    scopus 로고
    • The functional significance of microRNA-29c in patients with colorectal cancer: a potential circulating biomarker for predicting early relapse
    • Yang, I. P., Tsai, H. L., Huang, C. W., Huang, M. Y. et al., The functional significance of microRNA-29c in patients with colorectal cancer: a potential circulating biomarker for predicting early relapse. PLoS One 2013, 8, e66842.
    • (2013) PLoS One , vol.8 , pp. e66842
    • Yang, I.P.1    Tsai, H.L.2    Huang, C.W.3    Huang, M.Y.4
  • 43
    • 84883030137 scopus 로고    scopus 로고
    • Serum miR-21 as a diagnostic and prognostic biomarker in colorectal cancer
    • Toiyama, Y., Takahashi, M., Hur, K., Nagasaka, T. et al., Serum miR-21 as a diagnostic and prognostic biomarker in colorectal cancer. J. Natl. Cancer Inst. 2013, 105, 849-859.
    • (2013) J. Natl. Cancer Inst. , vol.105 , pp. 849-859
    • Toiyama, Y.1    Takahashi, M.2    Hur, K.3    Nagasaka, T.4
  • 44
    • 84882861857 scopus 로고    scopus 로고
    • Circulating cell-free DNA in serum as a biomarker of colorectal cancer
    • da Silva Filho, B. F., Gurgel, A. P., Neto, M. A., de Azevedo, D. A. et al., Circulating cell-free DNA in serum as a biomarker of colorectal cancer. J. Clin. Pathol. 2013, 66, 775-778.
    • (2013) J. Clin. Pathol. , vol.66 , pp. 775-778
    • da Silva Filho, B.F.1    Gurgel, A.P.2    Neto, M.A.3    de Azevedo, D.A.4
  • 45
    • 79955030814 scopus 로고    scopus 로고
    • Clinical significance of circulating tumor cells, including cancer stem-like cells, in peripheral blood for recurrence and prognosis in patients with Dukes' stage B and C colorectal cancer
    • Iinuma, H., Watanabe, T., Mimori, K., Adachi, M. et al., Clinical significance of circulating tumor cells, including cancer stem-like cells, in peripheral blood for recurrence and prognosis in patients with Dukes' stage B and C colorectal cancer. J. Clin. Oncol. 2011, 29, 1547-1555.
    • (2011) J. Clin. Oncol. , vol.29 , pp. 1547-1555
    • Iinuma, H.1    Watanabe, T.2    Mimori, K.3    Adachi, M.4
  • 46
    • 84884673445 scopus 로고    scopus 로고
    • Postoperative detection of circulating tumor cells predicts tumor recurrence in colorectal cancer patients
    • Galizia, G., Gemei, M., Orditura, M., Romano, C. et al., Postoperative detection of circulating tumor cells predicts tumor recurrence in colorectal cancer patients. J. Gastrointest. Surg. 2013, 17, 1809-1818.
    • (2013) J. Gastrointest. Surg. , vol.17 , pp. 1809-1818
    • Galizia, G.1    Gemei, M.2    Orditura, M.3    Romano, C.4
  • 47
    • 84881098877 scopus 로고    scopus 로고
    • Colorectal cancer diagnostics: biomarkers, cell-free DNA, circulating tumor cells and defining heterogeneous populations by single-cell analysis
    • Kin, C., Kidess, E., Poultsides, G. A., Visser, B. C., Jeffrey, S. S., Colorectal cancer diagnostics: biomarkers, cell-free DNA, circulating tumor cells and defining heterogeneous populations by single-cell analysis. Expert Rev. Mol. Diagn. 2013, 13, 581-599.
    • (2013) Expert Rev. Mol. Diagn. , vol.13 , pp. 581-599
    • Kin, C.1    Kidess, E.2    Poultsides, G.A.3    Visser, B.C.4    Jeffrey, S.S.5
  • 48
    • 84904330660 scopus 로고    scopus 로고
    • Colorectal cancer biomarker discovery and validation using LC-MS/MS-based proteomics in blood: truth or dare?
    • Reumer, A., Maes, E., Mertens, I., Cho, W. C. et al., Colorectal cancer biomarker discovery and validation using LC-MS/MS-based proteomics in blood: truth or dare? Expert Rev. Proteomics 2014, 11, 449-463.
    • (2014) Expert Rev. Proteomics , vol.11 , pp. 449-463
    • Reumer, A.1    Maes, E.2    Mertens, I.3    Cho, W.C.4
  • 49
    • 84899714616 scopus 로고    scopus 로고
    • Sorbitol dehydrogenase overexpression and other aspects of dysregulated protein expression in human precancerous colorectal neoplasms: a quantitative proteomics study
    • Uzozie, A., Nanni, P., Staiano, T., Grossmann, J. et al., Sorbitol dehydrogenase overexpression and other aspects of dysregulated protein expression in human precancerous colorectal neoplasms: a quantitative proteomics study. Mol. Cell. Proteomics 2014, 13, 1198-1218.
    • (2014) Mol. Cell. Proteomics , vol.13 , pp. 1198-1218
    • Uzozie, A.1    Nanni, P.2    Staiano, T.3    Grossmann, J.4
  • 50
    • 84881255398 scopus 로고    scopus 로고
    • Proteomic and cytokine plasma biomarkers for predicting progression from colorectal adenoma to carcinoma in human patients
    • Choi, J. W., Liu, H., Shin, D. H., Yu, G. I. et al., Proteomic and cytokine plasma biomarkers for predicting progression from colorectal adenoma to carcinoma in human patients. Proteomics 2013, 13, 2361-2374.
    • (2013) Proteomics , vol.13 , pp. 2361-2374
    • Choi, J.W.1    Liu, H.2    Shin, D.H.3    Yu, G.I.4
  • 51
    • 84880233927 scopus 로고    scopus 로고
    • Multiplexed cytokine profiling of serum for detection of colorectal cancer
    • Pengjun, Z., Xinyu, W., Feng, G., Xinxin, D. et al., Multiplexed cytokine profiling of serum for detection of colorectal cancer. Future Oncol. 2013, 9, 1017-1027.
    • (2013) Future Oncol. , vol.9 , pp. 1017-1027
    • Pengjun, Z.1    Xinyu, W.2    Feng, G.3    Xinxin, D.4
  • 52
    • 84860325202 scopus 로고    scopus 로고
    • Candidate biomarker verification: Critical examination of a serum protein pattern for human colorectal cancer
    • Albrethsen, J., Bogebo, R., Moller, C. H., Olsen, J. A. et al., Candidate biomarker verification: Critical examination of a serum protein pattern for human colorectal cancer. Proteomics Clin. Appl. 2012, 6, 182-189.
    • (2012) Proteomics Clin. Appl. , vol.6 , pp. 182-189
    • Albrethsen, J.1    Bogebo, R.2    Moller, C.H.3    Olsen, J.A.4
  • 53
    • 84896139983 scopus 로고    scopus 로고
    • Blood autoantibodies against tumor-associated antigens as biomarkers in early detection of colorectal cancer
    • Chen, H., Werner, S., Tao, S., Zoernig, I., Brenner, H., Blood autoantibodies against tumor-associated antigens as biomarkers in early detection of colorectal cancer. Cancer Lett. 2014, 346, 178-187.
    • (2014) Cancer Lett. , vol.346 , pp. 178-187
    • Chen, H.1    Werner, S.2    Tao, S.3    Zoernig, I.4    Brenner, H.5
  • 54
    • 84902105414 scopus 로고    scopus 로고
    • Pilot phase I/II personalized therapy trial for metastatic colorectal cancer: Evaluating the feasibility of protein pathway activation mapping for stratifying patients to therapy with imatinib and panitumumab
    • Pierobon, M., Silvestri, A., Spira, A., Reeder, A. et al., Pilot phase I/II personalized therapy trial for metastatic colorectal cancer: Evaluating the feasibility of protein pathway activation mapping for stratifying patients to therapy with imatinib and panitumumab. J. Proteome Res. 2014, 13, 2846-2855.
    • (2014) J. Proteome Res. , vol.13 , pp. 2846-2855
    • Pierobon, M.1    Silvestri, A.2    Spira, A.3    Reeder, A.4
  • 55
    • 84892591483 scopus 로고    scopus 로고
    • Global phosphotyrosine proteomics identifies PKCdelta as a marker of responsiveness to Src inhibition in colorectal cancer
    • McKinley, E. T., Liu, H., McDonald, W. H., Luo, W. et al., Global phosphotyrosine proteomics identifies PKCdelta as a marker of responsiveness to Src inhibition in colorectal cancer. PLoS One 2013, 8, e80207.
    • (2013) PLoS One , vol.8 , pp. e80207
    • McKinley, E.T.1    Liu, H.2    McDonald, W.H.3    Luo, W.4
  • 56
    • 84896706261 scopus 로고    scopus 로고
    • Organized proteomic heterogeneity in colorectal cancer liver metastases and implications for therapies
    • Turtoi, A., Blomme, A., Debois, D., Somja, J. et al., Organized proteomic heterogeneity in colorectal cancer liver metastases and implications for therapies. Hepatology 2014, 59, 924-934.
    • (2014) Hepatology , vol.59 , pp. 924-934
    • Turtoi, A.1    Blomme, A.2    Debois, D.3    Somja, J.4
  • 57
    • 84881485624 scopus 로고    scopus 로고
    • The secretome of colon cancer stem cells contains drug-metabolizing enzymes
    • Emmink, B. L., Verheem, A., Van Houdt, W. J., Steller, E. J.et al., The secretome of colon cancer stem cells contains drug-metabolizing enzymes. J. Proteomics 2013, 91, 84-96.
    • (2013) J. Proteomics , vol.91 , pp. 84-96
    • Emmink, B.L.1    Verheem, A.2    Van Houdt, W.J.3    Steller, E.J.4
  • 58
    • 84898600802 scopus 로고    scopus 로고
    • Proteomics of differential extraction fractions enriched for chromatin-binding proteins from colon adenoma and carcinoma tissues
    • Knol, J. C., de Wit, M., Albrethsen, J., Piersma, S. R. et al., Proteomics of differential extraction fractions enriched for chromatin-binding proteins from colon adenoma and carcinoma tissues. Biochim. Biophys. Acta 2014, 1844, 1034-1043.
    • (2014) Biochim. Biophys. Acta , vol.1844 , pp. 1034-1043
    • Knol, J.C.1    de Wit, M.2    Albrethsen, J.3    Piersma, S.R.4
  • 59
    • 84896777949 scopus 로고    scopus 로고
    • The roles of extracellular vesicles in cancer biology: toward the development of novel cancer biomarkers
    • Katsuda, T., Kosaka, N., Ochiya, T., The roles of extracellular vesicles in cancer biology: toward the development of novel cancer biomarkers. Proteomics 2014, 14, 412-425.
    • (2014) Proteomics , vol.14 , pp. 412-425
    • Katsuda, T.1    Kosaka, N.2    Ochiya, T.3
  • 60
    • 84884651647 scopus 로고    scopus 로고
    • Colon tumoursecretopeptidome: insights into endogenous proteolytic cleavage events in the colon tumour microenvironment
    • Greening, D. W., Kapp, E. A., Ji, H., Speed, T. P., Simpson, R. J., Colon tumoursecretopeptidome: insights into endogenous proteolytic cleavage events in the colon tumour microenvironment. Biochim. Biophys. Acta 2013, 1834, 2396-2407.
    • (2013) Biochim. Biophys. Acta , vol.1834 , pp. 2396-2407
    • Greening, D.W.1    Kapp, E.A.2    Ji, H.3    Speed, T.P.4    Simpson, R.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.