메뉴 건너뛰기




Volumn 27, Issue 3, 2003, Pages 303-310

CDX2, a highly sensitive and specific marker of adenocarcinomas of intestinal origin: An immunohistochemical survey of 476 primary and metastatic carcinomas

Author keywords

Carcinomas of unknown primary; Colonic adenocarcinoma; Immunohistochemistry; Nuclear transcription factor

Indexed keywords

CYTOSKELETON PROTEIN; MONOCLONAL ANTIBODY; TRANSCRIPTION FACTOR; TUMOR MARKER; VILLIN;

EID: 0037371192     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-200303000-00003     Document Type: Article
Times cited : (616)

References (26)
  • 1
    • 0025847287 scopus 로고
    • Distribution and pattern of expression of villin, a gastrointestinal-associated cytoskeletal protein, in human carcinomas: A study employing paraffin-embedded tissue
    • Bacchi CE, Gown AM. Distribution and pattern of expression of villin, a gastrointestinal-associated cytoskeletal protein, in human carcinomas: a study employing paraffin-embedded tissue. Lab Invest 1991;64:418-24.
    • (1991) Lab Invest , vol.64 , pp. 418-424
    • Bacchi, C.E.1    Gown, A.M.2
  • 2
    • 18244362326 scopus 로고    scopus 로고
    • Ectopic expression of homeodomain protein CDX2 in intestinal metaplasia and carcinomas of the stomach
    • Bai YQ, Yamamoto H, Akiyama Y, et al. Ectopic expression of homeodomain protein CDX2 in intestinal metaplasia and carcinomas of the stomach. Cancer Lett 2002;176:47-55.
    • (2002) Cancer Lett , vol.176 , pp. 47-55
    • Bai, Y.Q.1    Yamamoto, H.2    Akiyama, Y.3
  • 3
    • 0033594940 scopus 로고    scopus 로고
    • Reprogramming of intestinal differentiation and intercalary regeneration in Cdx2 mutant mice
    • Beck F, Chawengsaksophak K, Waring P, et al. Reprogramming of intestinal differentiation and intercalary regeneration in Cdx2 mutant mice. Proc Natl Acad Sci USA 1999;96:7318-23.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7318-7323
    • Beck, F.1    Chawengsaksophak, K.2    Waring, P.3
  • 4
    • 0029878961 scopus 로고    scopus 로고
    • Cytokeratins 7 and 20 and carcinoembryonic antigen in ovarian and colonic carcinoma
    • Berezowski K, Stastny JF, Kornstein MJ. Cytokeratins 7 and 20 and carcinoembryonic antigen in ovarian and colonic carcinoma. Mod Pathol 1996;9:426-9.
    • (1996) Mod Pathol , vol.9 , pp. 426-429
    • Berezowski, K.1    Stastny, J.F.2    Kornstein, M.J.3
  • 5
    • 0030937750 scopus 로고    scopus 로고
    • Homeosis and intestinal tumors in Cdx2 mutant mice
    • Chawengsaksophak K, James R, Hammond VE, et al. Homeosis and intestinal tumors in Cdx2 mutant mice. Nature 1997;386:84-7.
    • (1997) Nature , vol.386 , pp. 84-87
    • Chawengsaksophak, K.1    James, R.2    Hammond, V.E.3
  • 6
    • 0025607868 scopus 로고
    • Myogenic regulatory protein (MyoD1) expression in childhood solid tumors: Diagnostic utility in rhabdomyosarcoma
    • Dias P, Parham DM, Shapiro DN, et al. Myogenic regulatory protein (MyoD1) expression in childhood solid tumors: diagnostic utility in rhabdomyosarcoma. Am J Pathol 1990;137:1283-91.
    • (1990) Am J Pathol , vol.137 , pp. 1283-1291
    • Dias, P.1    Parham, D.M.2    Shapiro, D.N.3
  • 7
    • 0031446727 scopus 로고    scopus 로고
    • Cloning and chromosome assignment of the human CDX2 gene
    • Drummond F, Putt W, Fox M, et al. Cloning and chromosome assignment of the human CDX2 gene. Ann Hum Genet 1997;61: 393-400.
    • (1997) Ann Hum Genet , vol.61 , pp. 393-400
    • Drummond, F.1    Putt, W.2    Fox, M.3
  • 8
    • 0028123016 scopus 로고
    • Expression of thyroid-specific transcription factors TTF-1 and PAX-8 in human thyroid neoplasms
    • Fabbro D, Di L-C, Beltrami CA, et al. Expression of thyroid-specific transcription factors TTF-1 and PAX-8 in human thyroid neoplasms. Cancer Res 1994;54:4744-9.
    • (1994) Cancer Res , vol.54 , pp. 4744-4749
    • Fabbro, D.1    Di, L.-C.2    Beltrami, C.A.3
  • 9
    • 0029932829 scopus 로고    scopus 로고
    • TTF-1 gene expression in human lung tumors
    • Fabbro D, Di L-C, Stamerra O, et al. TTF-1 gene expression in human lung tumors. Eur J Cancer 1996;3:512-7.
    • (1996) Eur J Cancer , vol.3 , pp. 512-517
    • Fabbro, D.1    Di, L.-C.2    Stamerra, O.3
  • 10
    • 0025155425 scopus 로고
    • Estrogen and progesterone receptors in epithelial ovarian tumors
    • Glavind K, Grove A. Estrogen and progesterone receptors in epithelial ovarian tumors. APMIS 1990;98:916-20.
    • (1990) APMIS , vol.98 , pp. 916-920
    • Glavind, K.1    Grove, A.2
  • 11
    • 0035190672 scopus 로고    scopus 로고
    • Loss of CDX2 expression and microsatellite instability are prominent features of large cell minimally differentiated carcinomas of the colon
    • Hinoi T, Tani M, Lucas PC, et al. Loss of CDX2 expression and microsatellite instability are prominent features of large cell minimally differentiated carcinomas of the colon. Am J Pathol 2001; 159:2239-48.
    • (2001) Am J Pathol , vol.159 , pp. 2239-2248
    • Hinoi, T.1    Tani, M.2    Lucas, P.C.3
  • 12
    • 0344765471 scopus 로고    scopus 로고
    • Use of antibodies against estrogen and progesterone receptors to identify metastatic breast and ovarian carcinomas by conventional immunohistochemical and tyramide signal amplification methods
    • Kaufmann O, Kother S, Dietel M. Use of antibodies against estrogen and progesterone receptors to identify metastatic breast and ovarian carcinomas by conventional immunohistochemical and tyramide signal amplification methods. Mod Pathol 1998;11: 357-63.
    • (1998) Mod Pathol , vol.11 , pp. 357-363
    • Kaufmann, O.1    Kother, S.2    Dietel, M.3
  • 13
    • 0026340586 scopus 로고
    • The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the fetal brain
    • Lazzaro D, Price M, de Felice M, et al. The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the fetal brain. Development 1991;113: 1093-104.
    • (1991) Development , vol.113 , pp. 1093-1104
    • Lazzaro, D.1    Price, M.2    De Felice, M.3
  • 14
    • 0032577692 scopus 로고    scopus 로고
    • Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells
    • Mallo GV, Soubeyran P, Lissitzky JC, et al. Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells. J Biol Chem 1998;273:14030-6.
    • (1998) J Biol Chem , vol.273 , pp. 14030-14036
    • Mallo, G.V.1    Soubeyran, P.2    Lissitzky, J.C.3
  • 15
    • 17344392128 scopus 로고    scopus 로고
    • Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Downregulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis
    • Mallo GV, Rechreche H, Frigerio JM, et al. Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Downregulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis. Int J Cancer 1997;74: 35-44.
    • (1997) Int J Cancer , vol.74 , pp. 35-44
    • Mallo, G.V.1    Rechreche, H.2    Frigerio, J.M.3
  • 16
    • 0023635017 scopus 로고
    • Villin: A cytoskeletal protein and a differentiation marker expressed in some human adenocarcinomas
    • Moll R, Robine S, Dudouet B, et al. Villin: a cytoskeletal protein and a differentiation marker expressed in some human adenocarcinomas. Virchows Arch B Cell Pathol Incl Mol Pathol 1987;54: 155-69.
    • (1987) Virchows Arch B Cell Pathol Incl Mol Pathol , vol.54 , pp. 155-169
    • Moll, R.1    Robine, S.2    Dudouet, B.3
  • 17
    • 0013354143 scopus 로고    scopus 로고
    • Cdx-2 is a specific and sensitive marker of tumors of colonic origin
    • Murer B, Chilosi M, Barbareschi M, et al. Cdx-2 is a specific and sensitive marker of tumors of colonic origin. Mod Pathol 2002;5: 325A-6A.
    • (2002) Mod Pathol , vol.5
    • Murer, B.1    Chilosi, M.2    Barbareschi, M.3
  • 18
    • 0032424153 scopus 로고    scopus 로고
    • Unique expression patterns and alterations in the intestinal protein villin in primary and metastatic pulmonary adenocarcinomas
    • Nambu Y, Iannettoni MD, Orringer MB, et al. Unique expression patterns and alterations in the intestinal protein villin in primary and metastatic pulmonary adenocarcinomas. Mol Carcinog 1998; 23:234-42.
    • (1998) Mol Carcinog , vol.23 , pp. 234-242
    • Nambu, Y.1    Iannettoni, M.D.2    Orringer, M.B.3
  • 19
    • 0035154834 scopus 로고    scopus 로고
    • The homeobox gene CDX2 in colorectal carcinoma: A genetic analysis
    • Sivagnanasundaram S, Islam I, Talbot I, et al. The homeobox gene CDX2 in colorectal carcinoma: a genetic analysis. Br J Cancer 2001;84:218-25.
    • (2001) Br J Cancer , vol.84 , pp. 218-225
    • Sivagnanasundaram, S.1    Islam, I.2    Talbot, I.3
  • 20
    • 0033564467 scopus 로고    scopus 로고
    • Colonic hamartoma development by anomalous duplication in Cdx2 knockout mice
    • Tamai Y, Nakajima R, Ishikawa T, et al. Colonic hamartoma development by anomalous duplication in Cdx2 knockout mice. Cancer Res 1999;59:2965-70.
    • (1999) Cancer Res , vol.59 , pp. 2965-2970
    • Tamai, Y.1    Nakajima, R.2    Ishikawa, T.3
  • 21
    • 0031933602 scopus 로고    scopus 로고
    • Value of a panel of antibodies to identify the primary origin of adenocarcinomas presenting as bladder carcinoma
    • Torenbeek R, Lagendijk JH, Van Diest PJ, et al. Value of a panel of antibodies to identify the primary origin of adenocarcinomas presenting as bladder carcinoma. Histopathology 1998;32:20-7.
    • (1998) Histopathology , vol.32 , pp. 20-27
    • Torenbeek, R.1    Lagendijk, J.H.2    Van Diest, P.J.3
  • 22
    • 0029013612 scopus 로고
    • Coordinate expression of cytokeratins 7 and 20 define unique subsets of carcinoma
    • Wang N-P, Zee S, Zarbo RJ, et al. Coordinate expression of cytokeratins 7 and 20 define unique subsets of carcinoma. Appl Immunohistochem 1995;3:99-107.
    • (1995) Appl Immunohistochem , vol.3 , pp. 99-107
    • Wang, N.-P.1    Zee, S.2    Zarbo, R.J.3
  • 23
    • 0028845760 scopus 로고
    • Expression of myogenic regulatory proteins (myogenin and MyoD1) in small blue round cell tumors of childhood
    • Wang NP, Marx J, McNutt MA, et al. Expression of myogenic regulatory proteins (myogenin and MyoD1) in small blue round cell tumors of childhood. Am J Pathol 1995;147:1799-810.
    • (1995) Am J Pathol , vol.147 , pp. 1799-1810
    • Wang, N.P.1    Marx, J.2    McNutt, M.A.3
  • 24
    • 0023837466 scopus 로고
    • Localization of villin, a cytoskeletal protein specific to microvilli, in human ileum and colon and in colonic neoplasms
    • West AB, Isaac CA, Carboni JM, et al. Localization of villin, a cytoskeletal protein specific to microvilli, in human ileum and colon and in colonic neoplasms. Gastroenterology 1988;94: 343-52.
    • (1988) Gastroenterology , vol.94 , pp. 343-352
    • West, A.B.1    Isaac, C.A.2    Carboni, J.M.3
  • 25
    • 7344243778 scopus 로고    scopus 로고
    • CDX2, a human homologue of Drosophila caudal, is mutated in both alleles in a replication error positive colorectal cancer
    • Wicking C, Simms LA, Evans T, et al. CDX2, a human homologue of Drosophila caudal, is mutated in both alleles in a replication error positive colorectal cancer. Oncogene 1998;17:657-9.
    • (1998) Oncogene , vol.17 , pp. 657-659
    • Wicking, C.1    Simms, L.A.2    Evans, T.3
  • 26
    • 0032950713 scopus 로고    scopus 로고
    • Genomic structure and alterations of homeobox gene CDX2 in colorectal carcinomas
    • Yagi OK, Akiyama Y, Yuasa Y. Genomic structure and alterations of homeobox gene CDX2 in colorectal carcinomas. Br J Cancer 1999;79:440-4.
    • (1999) Br J Cancer , vol.79 , pp. 440-444
    • Yagi, O.K.1    Akiyama, Y.2    Yuasa, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.