Diphenylpyrazoles as replication protein A inhibitors

ACS Medicinal Chemistry Letters

Volumn 6, Issue 2, 2015, Pages 140-145

  Waterson, Alex G ^a,b   Kennedy, J Phillip ^a,c   Patrone, James D ^a   Pelz, Nicholas F ^a   Feldkamp, Michael D ^a   Frank, Andreas O ^a,d   Vangamudi, Bhavatarini ^a,e   Souza Fagundes, Elaine M ^a,f   Rossanese, Olivia W ^a   Chazin, Walter J ^a   Fesik, Stephen W ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c Revance TherapeuticsInc   (United States)

^d NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^e UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^f FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

fragment based discovery; medicinal chemistry; Replication protein A

Indexed keywords

DIPHENYLPYRAZOLE; PROTEIN INHIBITOR; PYRAZOLE DERIVATIVE; REPLICATION FACTOR A; UNCLASSIFIED DRUG;

ARTICLE; DNA DAMAGE; DRUG SYNTHESIS; HETERONUCLEAR SINGLE QUANTUM COHERENCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

EUKARYOTA;

EID: 84922948142     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml5003629     Document Type: Article

References (13)

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