SCOPUS 정보 검색 플랫폼

Molecular Informatics

Volumn 30, Issue 4, 2011, Pages 298-306

Compound design by fragment-linking

(4) Ichihara, Osamu a Barker, John a Law, Richard J a Whittaker, Mark a

a EVOTEC UK LTD (United Kingdom)

Author keywords

Drug discovery; Fragment linking; Fragment molecular orbital; Superadditivity; X ray crystallography

Indexed keywords

BINDERS; BINDING ENERGY; BINDING SITES; FREE ENERGY; MOLECULAR ORBITALS;

BINDING AFFINITIES; BINDING FREE ENERGY; BINDING MODES; DRUG DISCOVERY; FRAGMENT LINKING; FRAGMENT MOLECULAR ORBITAL; H-BONDS; LINKING COEFFICIENT; SIMPLE++; SUPERADDITIVITY;

X RAY CRYSTALLOGRAPHY;

AVIDIN; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR; MACROPHAGE ELASTASE; PANTOTHENIC ACID; PEPTIDE FRAGMENT; RNA 23S; STROMELYSIN; THROMBIN;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; FRAGMENT MOLECULAR ORBITAL; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HYDROGEN BOND; HYDROPHOBICITY; LIPOPHILICITY; PARAMETER; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; QUANTUM MECHANICS; SCREENING; STRUCTURE ANALYSIS; STUDY DESIGN; TECHNIQUE; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

EID: 79958840084 PISSN: 18681743 EISSN: 18681751 Source Type: Journal
DOI: 10.1002/minf.201000174 Document Type: Article

Times cited : (80)

References (53)

1
- 46849089254
- M. Congreve, G. Chessari, D. Tisi, A. J. Woodhead, J. Med. Chem. 2008, 51, 3661-3680
- (2008) J. Med. Chem. , vol.51 , pp. 3661-3680
- Congreve, M.¹ Chessari, G.² Tisi, D.³ Woodhead, A.J.⁴

2
- 33847381100
- P. J. Hajduk, J. Greer, Nat. Rev. Drug Discov. 2007, 6, 211 -219
- (2007) Nat. Rev. Drug Discov. , vol.6 , pp. 211-219
- Hajduk, P.J.¹ Greer, J.²

3
- 36248997755
- A. A. Alex, M. M. Flocco, Curr. Top. Med. Chem. 2007, 7, 1544-1567
- (2007) Curr. Top. Med. Chem. , vol.7 , pp. 1544-1567
- Alex, A.A.¹ Flocco, M.M.²

4
- 44949211332
- T. Hesterkamp, M. Whittaker, Curr. Opin. Chem. Biol. 2008, 12, 260-268
- (2008) Curr. Opin. Chem. Biol. , vol.12 , pp. 260-268
- Hesterkamp, T.¹ Whittaker, M.²

5
- 85161793397
- D. C. Rees, M. Congreve, C. W. Murray, R. Carr, Nat. Rev. Drug Discov. 2004, 3, 211-219
- (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 211-219
- Rees, D.C.¹ Congreve, M.² Murray, C.W.³ Carr, R.⁴

6
- 78650722321
- f) M. Whittaker, R. J. Law, O. Ichihara, T. Hesterkamp, D. Hallett, Drug Discov. Today: Technol. 2010, 7, e163-e171.
- (2010) Drug Discov. Today: Technol. , vol.7
- Whittaker, M.¹ Law, R.J.² Ichihara, O.³ Hesterkamp, T.⁴ Hallett, D.⁵

7
- 36248932680
- E. R. Zartler, H. Mo, Curr. Top. Med. Chem. 2007, 7, 1592-1599
- (2007) Curr. Top. Med. Chem. , vol.7 , pp. 1592-1599
- Zartler, E.R.¹ Mo, H.²

8
- 36348998688
- b) T. Hesterkamp, J. Barker, A. Davenport, M. Whittaker, Curr. Top. Med. Chem. 2007, 7, 1582-1591
- (2007) Curr. Top. Med. Chem. , vol.7 , pp. 1582-1591
- Hesterkamp, T.¹ Barker, J.² Davenport, A.³ Whittaker, M.⁴

9
- 36249028775
- c) T. Neumann, H. D. Junker, K. Schmidt, R. Sekul, Curr. Top. Med. Chem. 2007, 7, 1630-1642.
- (2007) Curr. Top. Med. Chem. , vol.7 , pp. 1630-1642
- Neumann, T.¹ Junker, H.D.² Schmidt, K.³ Sekul, R.⁴

10
- 0036051992
- a) T. L. Blundell, H. Jhoti, C. Abell, Nat. Rev. Drug Discov. 2002, 1, 45-54
- (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 45-54
- Blundell, T.L.¹ Jhoti, H.² Abell, C.³

11
- 33846460839
- b) A. M. Hassell, G. An, R. K. Bledsoe, J. M. Bynum, H. L. Carter, S. J. J. Deng, R. T. Gampe, T. E. Grisard, K. P. Madauss, R. T. Nolte, W. J. Rocque, L. Wang, K. L. Weaver, S. P. Williams, G. B. Wisely, R. Xu, L. M. Shewchuk, Acta Crystallogr. D Biol. Crystallogr. 2007, 63, 72-79
- (2007) Acta Crystallogr. D Biol. Crystallogr. , vol.63 , pp. 72-79
- Hassell, A.M.¹ An, G.² Bledsoe, R.K.³ Bynum, J.M.⁴ Carter, H.L.⁵ Deng, S.J.J.⁶ Gampe, R.T.⁷ Grisard, T.E.⁸ Madauss, K.P.⁹ Nolte, R.T.¹⁰ Rocque, W.J.¹¹ Wang, L.¹² Weaver, K.L.¹³ Williams, S.P.¹⁴ Wisely, G.B.¹⁵ Xu, R.¹⁶ Shewchuk, L.M.¹⁷

12
- 67649878781
- c) J. J. Barker, B. Felicetti, T. Hesterkamp, M. Whittaker, Chim. Oggi Chem. Today 2009, 27, 32-36.
- (2009) Chim. Oggi Chem. Today , vol.27 , pp. 32-36
- Barker, J.J.¹ Felicetti, B.² Hesterkamp, T.³ Whittaker, M.⁴

13
- 0016415230
- N. M. Green, Adv. Protein Chem. 1975, 29, 85-133.
- (1975) Adv. Protein Chem. , vol.29 , pp. 85-133
- Green, N.M.¹

14
- 77952713014
- V. Borsi, V. Calderone, M. Fragai, C. O. Luchinat, N. Sarti, J. Med. Chem. 2010, 53, 4285-4289.
- (2010) J. Med. Chem. , vol.53 , pp. 4285-4289
- Borsi, V.¹ Calderone, V.² Fragai, M.³ Luchinat, C.O.⁴ Sarti, N.⁵

15
- 16944365890
- P. J. Hajduk, G. Sheppard, D. G. Nettesheim, E. T. Olejniczak, S. B. Shuker, R. P. Meadows, D. H. Steinman, G. M. Carrera, Jr., P. A. Marcotte, J. Severin, K. Walter, H. Smith, E. Gubbins, R. Simmer, T. F. Holzman, D. W. Morgan, S. K. Davidsen, J. B. Summers, S. W. Fesik, J. Am. Chem. Soc. 1997, 119, 5818-5827.
- (1997) J. Am. Chem. Soc. , vol.119 , pp. 5818-5827
- Hajduk, P.J.¹ Sheppard, G.² Nettesheim, D.G.³ Olejniczak, E.T.⁴ Shuker, S.B.⁵ Meadows, R.P.⁶ Steinman, D.H.⁷ Carrera Jr., G.M.⁸ Marcotte, P.A.⁹ Severin, J.¹⁰ Walter, K.¹¹ Smith, H.¹² Gubbins, E.¹³ Simmer, R.¹⁴ Holzman, T.F.¹⁵ Morgan, D.W.¹⁶ Davidsen, S.K.¹⁷ Summers, J.B.¹⁸ Fesik, S.W.¹⁹

16
- 33144470698
- N. Howard, C. Abell, W. Blakemore, G. Chessari, M. Congreve, S. Howard, H. Jhoti, C. W. Murray, L. C. A. Seavers, R. L. M. van Montfort, J. Med. Chem. 2006, 49, 1346-1355.
- (2006) J. Med. Chem. , vol.49 , pp. 1346-1355
- Howard, N.¹ Abell, C.² Blakemore, W.³ Chessari, G.⁴ Congreve, M.⁵ Howard, S.⁶ Jhoti, H.⁷ Murray, C.W.⁸ Seavers, L.C.A.⁹ Van Montfort, R.L.M.¹⁰

17
- 77957655200
- J. J. Barker, O. Barker, S. M. Courtney, M. Gardiner, T. Hesterkamp, O. Ichihara, O. Mather, C. A. G. N. Montalbetti, A. M üller, M. Varasi, M. Whittaker, C. J. Yarnold, ChemMedChem, 2010, 5, 1697-1700.
- (2010) ChemMedChem , vol.5 , pp. 1697-1700
- Barker, J.J.¹ Barker, O.² Courtney, S.M.³ Gardiner, M.⁴ Hesterkamp, T.⁵ Ichihara, O.⁶ Mather, O.⁷ Montalbetti, C.A.G.N.⁸ Müller, A.⁹ Varasi, M.¹⁰ Whittaker, M.¹¹ Yarnold, C.J.¹²

18
- 70350346470
- A. W. Hung, H. L. Silvestre, S. Wen, A. Ciulli, T. L. Blundell, C. Abell, Angew. Chem. Int. Ed. 2009, 48, 8452-8456.
- (2009) Angew. Chem. Int. Ed. , vol.48 , pp. 8452-8456
- Hung, A.W.¹ Silvestre, H.L.² Wen, S.³ Ciulli, A.⁴ Blundell, T.L.⁵ Abell, C.⁶

19
- 0034646370
- M. D. Maly, I. C. Choong, J. A. Ellman, Proc. Natl. Acad. Sci. USA 2000, 97, 2419-2424.
- (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 2419-2424
- Maly, M.D.¹ Choong, I.C.² Ellman, J.A.³

20
- 0029836953
- S. B. Shuker, P. J. Hajduk, R. P. Meadows, S. W. Fesik, Science 1996, 274, 1531-1534.
- (1996) Science , vol.274 , pp. 1531-1534
- Shuker, S.B.¹ Hajduk, P.J.² Meadows, R.P.³ Fesik, S.W.⁴

21
- 0037194620
- E. E. Swayze, E. A. Jefferson, K. A. Sannes-Lowery, L. B. Blyn, L. M. Risen, S. Arakawa, S. A. Osgood, S. A. Hofstadler, R. H. Griffey, J. Med. Chem. 2002, 45, 3816-3819.
- (2002) J. Med. Chem. , vol.45 , pp. 3816-3819
- Swayze, E.E.¹ Jefferson, E.A.² Sannes-Lowery, K.A.³ Blyn, L.B.⁴ Risen, L.M.⁵ Arakawa, S.⁶ Osgood, S.A.⁷ Hofstadler, S.A.⁸ Griffey, R.H.⁹

22
- 0030829408
- E. T. Olejniczak, P. J. Hajduk, P. A. Marcotte, D. G. Nettesheim, R. P. Meadows, R. Edalji, T. F. Holzman, S. W. Fesik, J. Am. Chem. Soc. 1997, 119, 5828-5832.
- (1997) J. Am. Chem. Soc. , vol.119 , pp. 5828-5832
- Olejniczak, E.T.¹ Hajduk, P.J.² Marcotte, P.A.³ Nettesheim, D.G.⁴ Meadows, R.P.⁵ Edalji, R.⁶ Holzman, T.F.⁷ Fesik, S.W.⁸

23
- 85161738064
- P. J. Hajduk, A. Gomtsyan, S. Didomenico, M. Cowart, E. K. Bayburt, L. Solomon, J. Severin, R. Smith, K. Walter, T. F. Holzman, A. Stewart, S. McGaraughty, M. F. Jarvis, E. A. Kowaluk, S. W. Fesik, J. Med. Chem. 2000, 43, 4718-4786.
- (2000) J. Med. Chem. , vol.43 , pp. 4718-4786
- Hajduk, P.J.¹ Gomtsyan, A.² Didomenico, S.³ Cowart, M.⁴ Bayburt, E.K.⁵ Solomon, L.⁶ Severin, J.⁷ Smith, R.⁸ Walter, K.⁹ Holzman, T.F.¹⁰ Stewart, A.¹¹ McGaraughty, S.¹² Jarvis, M.F.¹³ Kowaluk, E.A.¹⁴ Fesik, S.W.¹⁵

24
- 0242417581
- G. Liu, Z. Xin, Z. Pei, P. J. Hajduk, C. Abad-Zapatero, C. W. Hutchins, H. Zhao, T. H. Lubben, S. J. Ballaron, D. L. Haasch, W. Kaszubska, C. M. Rondinone, J. M. Trevillyan, M. R. Jirousek, J. Am. Chem. Soc. 2003, 125, 4087-4096.
- (2003) J. Am. Chem. Soc. , vol.125 , pp. 4087-4096
- Liu, G.¹ Xin, Z.² Pei, Z.³ Hajduk, P.J.⁴ Abad-Zapatero, C.⁵ Hutchins, C.W.⁶ Zhao, H.⁷ Lubben, T.H.⁸ Ballaron, S.J.⁹ Haasch, D.L.¹⁰ Kaszubska, W.¹¹ Rondinone, C.M.¹² Trevillyan, J.M.¹³ Jirousek, M.R.¹⁴

25
- 0141680857
- G. Liu, Z. Xin, Z. Pei, P. J. Hajduk, C. Abad-Zapatero, C. W. Hutchins, H. Zhao, T. H. Lubben, S. J. Ballaron, D. L. Haasch, W. Kaszubska, C. M. Rondinone, J. M. Trevillyan, M. R. Jirousek, J. Med. Chem. 2003, 46, 4232-4235.
- (2003) J. Med. Chem. , vol.46 , pp. 4232-4235
- Liu, G.¹ Xin, Z.² Pei, Z.³ Hajduk, P.J.⁴ Abad-Zapatero, C.⁵ Hutchins, C.W.⁶ Zhao, H.⁷ Lubben, T.H.⁸ Ballaron, S.J.⁹ Haasch, D.L.¹⁰ Kaszubska, W.¹¹ Rondinone, C.M.¹² Trevillyan, J.M.¹³ Jirousek, M.R.¹⁴

26
- 20444486559
- T. Oltersdorf, S. W. Elmore, A. R. Shoemaker, R. C. Armstrong, D. J. Augeri, B. A. Belli, M. Bruncko, T. L. Deckwerth, J. Dinges, P. J. Hajduk, M. K. Joseph, S. Kitada, S. J. Korsmeyer, A. R. Kunzer, A. Letai, C. Li, M. J. Mitten, D. G. Nettesheim, S. Ng, P. M. Nimmer, J. M. O'Connor, A. Oleksijew, A. M. Petros, J. C. Reed, W. Shen, S. K. Tahir, C. B. Thompson, K. J. Tomaselli, B. Wang, M. D. Wendt, H. Zhang, S. W. Fesik, S. H. Rosenberg, Nature 2005, 435, 677-681.
- (2005) Nature , vol.435 , pp. 677-681
- Oltersdorf, T.¹ Elmore, S.W.² Shoemaker, A.R.³ Armstrong, R.C.⁴ Augeri, D.J.⁵ Belli, B.A.⁶ Bruncko, M.⁷ Deckwerth, T.L.⁸ Dinges, J.⁹ Hajduk, P.J.¹⁰ Joseph, M.K.¹¹ Kitada, S.¹² Korsmeyer, S.J.¹³ Kunzer, A.R.¹⁴ Letai, A.¹⁵ Li, C.¹⁶ Mitten, M.J.¹⁷ Nettesheim, D.G.¹⁸ Ng, S.¹⁹ Nimmer, P.M.²⁰ more..

27
- 31544467109
- A. M. Petros, J. Dinges, D. J. Augeri, S. A. Baumeister, D. A. Betebenner, M. G. Bures, S. W. Elmore, P. J. Hajduk, M. K. Joseph, S. K. Landis, D. G. Nettesheim, S. H. Rosenberg, W. Shen, S. Thomas, X. Wang, I. Zanze, H. Zhang, S. W. Fesik, J. Med. Chem. 2006, 49, 656-663.
- (2006) J. Med. Chem. , vol.49 , pp. 656-663
- Petros, A.M.¹ Dinges, J.² Augeri, D.J.³ Baumeister, S.A.⁴ Betebenner, D.A.⁵ Bures, M.G.⁶ Elmore, S.W.⁷ Hajduk, P.J.⁸ Joseph, M.K.⁹ Landis, S.K.¹⁰ Nettesheim, D.G.¹¹ Rosenberg, S.H.¹² Shen, W.¹³ Thomas, S.¹⁴ Wang, X.¹⁵ Zanze, I.¹⁶ Zhang, H.¹⁷ Fesik, S.W.¹⁸

28
- 0019407381
- W. P. Jencks, Proc. Natl. Acad. Sci. USA 1981, 78, 4046-4050.
- (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 4046-4050
- Jencks, W.P.¹

29
- 0036821028
- a) C. W. Murray, M. L. Verdonk, J. Comput. Aided Mol. Des. 2002, 16, 741-753
- (2002) J. Comput. Aided Mol. Des. , vol.16 , pp. 741-753
- Murray, C.W.¹ Verdonk, M.L.²

30
- 84870998578
- Eds: W. Jahnke, D. A. Erlanson, WILEY -VCH, Weinheim
- b) C. W. Murray, M. L. Verdonk, Fragmentbased Approaches in Drug Discovery (Eds: W. Jahnke, D. A. Erlanson), WILEY-VCH, Weinheim, 2006, pp. 55-66.
- (2006) Fragmentbased Approaches in Drug Discovery , pp. 55-66
- Murray, C.W.¹ Verdonk, M.L.²

31
- 42449147105
- C. H. Rçhrig, C. Loch, J.-Y. Guan, G. Siegal, M. Overhand, Chem- MedChem 2007, 2, 1054-1070.
- (2007) Chem- MedChem , vol.2 , pp. 1054-1070
- Rçhrig, C.H.¹ Loch, C.² Guan, J.-Y.³ Siegal, G.⁴ Overhand, M.⁵

32
- 67649341990
- G. Chessaria, A. J. Woodhead, Drug Discov. Today 2009, 14, 668-675.
- (2009) Drug Discov. Today , vol.14 , pp. 668-675
- Chessaria, G.¹ Woodhead, A.J.²

33
- 77249161707
- V. Sandanayaka, B. Mamat, R. K. Mishra, J. Winger, M. Krohn, L. Zhou, M. Keyvan, L. Enache, D. Sullins, E. Onua, J. Zhang, G. Halldorsdottir, H. Sigthorsdottir, A. Thorlaksdottir, G. Sigthorsson, M. Thorsteinnsdottir, D. R. Davies, L. J. Stewart, D. E. Zembower, T. Andresson, A. S. Kiselyov, J. Singh, M. E. Gurney, J. Med. Chem. 2010, 53, 573-585.
- (2010) J. Med. Chem. , vol.53 , pp. 573-585
- Sandanayaka, V.¹ Mamat, B.² Mishra, R.K.³ Winger, J.⁴ Krohn, M.⁵ Zhou, L.⁶ Keyvan, M.⁷ Enache, L.⁸ Sullins, D.⁹ Onua, E.¹⁰ Zhang, J.¹¹ Halldorsdottir, G.¹² Sigthorsdottir, H.¹³ Thorlaksdottir, A.¹⁴ Sigthorsson, G.¹⁵ Thorsteinnsdottir, M.¹⁶ Davies, D.R.¹⁷ Stewart, L.J.¹⁸ Zembower, D.E.¹⁹ Andresson, T.²⁰ more..

34
- 77950816491
- P. Sledz, H. L. Silvestre, A. W. Hung, A. Ciulli, T. L. Blundell, C. Abell, J. Am. Chem. Soc. 2010, 132, 4544-4545.
- (2010) J. Am. Chem. Soc. , vol.132 , pp. 4544-4545
- Sledz, P.¹ Silvestre, H.L.² Hung, A.W.³ Ciulli, A.⁴ Blundell, T.L.⁵ Abell, C.⁶

35
- 33646253701
- J. W. Bode, J. Am. Chem. Soc. 2004, 126, 15317-15317.
- (2004) J. Am. Chem. Soc. , vol.126 , pp. 15317-15317
- Bode, J.W.¹

36
- 67349171544
- S. Chung, J. B. Parker, M. Bianchet, L. M. Amzel, J. T. Stivers, Nat. Chem. Biol. 2009, 5, 407-413.
- (2009) Nat. Chem. Biol. , vol.5 , pp. 407-413
- Chung, S.¹ Parker, J.B.² Bianchet, M.³ Amzel, L.M.⁴ Stivers, J.T.⁵

37
- 33846595219
- D. G. Fedorov, K. Kitaura, J. Comp. Chem. 2006, 28, 222-237.
- (2006) J. Comp. Chem. , vol.28 , pp. 222-237
- Fedorov, D.G.¹ Kitaura, K.²

38
- 0000721543
- a) K. Kitaura, E. Ikeo, T. Asada, T. Nakano, M. Uebayasi, Chem. Phys. Lett. 1999, 313, 701-706
- (1999) Chem. Phys. Lett. , vol.313 , pp. 701-706
- Kitaura, K.¹ Ikeo, E.² Asada, T.³ Nakano, T.⁴ Uebayasi, M.⁵

39
- 34548243709
- D. G. Fedorov, K. Kitaura, J. Phys. Chem. A 2007, 111, 6904-6914.
- (2007) J. Phys. Chem. A , vol.111 , pp. 6904-6914
- Fedorov, D.G.¹ Kitaura, K.²

40
- 0029745052
- a) P. Mecozzi, A. P. West, Jr., D. A. Dougherty, Proc. Natl. Acad. Sci. USA 1996, 93, 10566-10571
- (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 10566-10571
- Mecozzi, P.¹ West Jr., A.P.² Dougherty, D.A.³

41
- 0033578302
- b) J. P. Gallivan, D. A. Dougherty, Proc. Natl. Acad. Sci. USA 1999, 96, 9459-9464.
- (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 9459-9464
- Gallivan, J.P.¹ Dougherty, D.A.²

42
- 56349092413
- T. Ozawa, E. Tsuji, M. Ozawa, C. Handa, H. Mukaiyama, T. Nishimura, S. Kobayashi, K. Okazaki, Bioorg. Med. Chem. 2008, 16, 10311-10318.
- (2008) Bioorg. Med. Chem. , vol.16 , pp. 10311-10318
- Ozawa, T.¹ Tsuji, E.² Ozawa, M.³ Handa, C.⁴ Mukaiyama, H.⁵ Nishimura, T.⁶ Kobayashi, S.⁷ Okazaki, K.⁸

43
- 70350399974
- Y. N. Imai, Y. Inoue, I. Nakanishi, K. Kitaura, QSAR Comb. Sci. 2009, 28, 869-873.
- (2009) QSAR Comb. Sci. , vol.28 , pp. 869-873
- Imai, Y.N.¹ Inoue, Y.² Nakanishi, I.³ Kitaura, K.⁴

44
- 77955875331
- G. J. Bartlett, A. Choudhary, R. T. Raines, D. N. Woolfson, Nat. Chem. Biol. 2010, 6, 615-620.
- (2010) Nat. Chem. Biol. , vol.6 , pp. 615-620
- Bartlett, G.J.¹ Choudhary, A.² Raines, R.T.³ Woolfson, D.N.⁴

45
- 36849107181
- a) K. Morokuma, J. Chem. Phys. 1971, 55, 1236
- (1971) J. Chem. Phys. , vol.55 , pp. 1236
- Morokuma, K.¹

46
- 84987133653
- b) K. Kitaura, K. Morokuma, Int. J. Quantum. Chem. 1976, 10, 325.
- (1976) Int. J. Quantum. Chem. , vol.10 , pp. 325
- Kitaura, K.¹ Morokuma, K.²

47
- 33748790698
- a) M. Suenaga, J. Comput. Chem. Jpn. 2005, 4, 25-32
- (2005) J. Comput. Chem. Jpn. , vol.4 , pp. 25-32
- Suenaga, M.¹

48
- 67650754298
- a) M. Suenaga, J. Comput. Chem. Jpn. 2005, 4, 25-32
- (2008) J. Comput. Chem. Jpn. , vol.7 , pp. 33-53
- Suenaga, M.¹

49
- 33847088301
- H. Umeyama, K. Morokuma, J. Am. Chem. Soc. 1977, 99, 1316.
- (1977) J. Am. Chem. Soc. , vol.99 , pp. 1316
- Umeyama, H.¹ Morokuma, K.²

50
- 56549131177
- a) T. S. G. Olsson, M. A. Williams, W. R. Pitt, J. E. Ladbury, J. Mol. Biol. 2008, 384, 1002-1017
- (2008) J. Mol. Biol. , vol.384 , pp. 1002-1017
- Olsson, T.S.G.¹ Williams, M.A.² Pitt, W.R.³ Ladbury, J.E.⁴

51
- 52049123291
- b) E. Freire, Drug Discov. Today 2008, 13, 869-874
- (2008) Drug Discov. Today , vol.13 , pp. 869-874
- Freire, E.¹

52
- 73449087370
- c) A. D. Scott, C. Phillips, A. Alex, M. Flocco, A. Bent, A. Randall, R. O'Brien, L. Damian, L. H. Jones, ChemMedChem 2009, 4, 1985-1989
- (2009) ChemMedChem , vol.4 , pp. 1985-1989
- Scott, A.D.¹ Phillips, C.² Alex, A.³ Flocco, M.⁴ Bent, A.⁵ Randall, A.⁶ O'brien, R.⁷ Damian, L.⁸ Jones, L.H.⁹

53
- 77957229353
- d) G. G. Ferenczy, G. M. Keserü, Drug Discov. Today 2010, 15, 919-932.
- (2010) Drug Discov. Today , vol.15 , pp. 919-932
- Ferenczy, G.G.¹ Keserü, G.M.²

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.