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Volumn 65, Issue 6, 2015, Pages 560-569

Irreversible triggers for hypertrophic cardiomyopathy are established in the early postnatal period

Author keywords

genetics; mouse models

Indexed keywords

DOXYCYCLINE; MYOSIN HEAVY CHAIN ALPHA; CARRIER PROTEIN; MYOSIN HEAVY CHAIN; RNA;

EID: 84922933756     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2014.10.069     Document Type: Article
Times cited : (24)

References (34)
  • 1
    • 79953037494 scopus 로고    scopus 로고
    • Identifying sarcomere gene mutations in hypertrophic cardiomyopathy: A personal history
    • C.E. Seidman, and J.G. Seidman Identifying sarcomere gene mutations in hypertrophic cardiomyopathy: a personal history Circ Res 108 2011 743 750
    • (2011) Circ Res , vol.108 , pp. 743-750
    • Seidman, C.E.1    Seidman, J.G.2
  • 2
    • 79959937543 scopus 로고    scopus 로고
    • Disease pathways and novel therapeutic targets in hypertrophic cardiomyopathy
    • H. Ashrafian, W.J. McKenna, and H. Watkins Disease pathways and novel therapeutic targets in hypertrophic cardiomyopathy Circ Res 109 2011 86 96
    • (2011) Circ Res , vol.109 , pp. 86-96
    • Ashrafian, H.1    McKenna, W.J.2    Watkins, H.3
  • 3
    • 0025040392 scopus 로고
    • A molecular basis for familial hypertrophic cardiomyopathy: A beta cardiac myosin heavy chain gene missense mutation
    • A.A. Geisterfer-Lowrance, S. Kass, and G. Tanigawa A molecular basis for familial hypertrophic cardiomyopathy: a beta cardiac myosin heavy chain gene missense mutation Cell 62 1990 999 1006
    • (1990) Cell , vol.62 , pp. 999-1006
    • Geisterfer-Lowrance, A.A.1    Kass, S.2    Tanigawa, G.3
  • 4
    • 0030067394 scopus 로고    scopus 로고
    • A mouse model of familial hypertrophic cardiomyopathy
    • A.A. Geisterfer-Lowrance, M. Christe, and D.A. Conner A mouse model of familial hypertrophic cardiomyopathy Science 272 1996 731 734
    • (1996) Science , vol.272 , pp. 731-734
    • Geisterfer-Lowrance, A.A.1    Christe, M.2    Conner, D.A.3
  • 5
    • 0033017175 scopus 로고    scopus 로고
    • The pathogenesis of familial hypertrophic cardiomyopathy: Early and evolving effects from an alpha-cardiac myosin heavy chain missense mutation
    • D. Georgakopoulos, M.E. Christe, M. Giewat, C.E. Seidman, J.G. Seidman, and D.A. Kass The pathogenesis of familial hypertrophic cardiomyopathy: early and evolving effects from an alpha-cardiac myosin heavy chain missense mutation Nat Med 5 1999 327 330
    • (1999) Nat Med , vol.5 , pp. 327-330
    • Georgakopoulos, D.1    Christe, M.E.2    Giewat, M.3    Seidman, C.E.4    Seidman, J.G.5    Kass, D.A.6
  • 6
    • 0032943836 scopus 로고    scopus 로고
    • Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene
    • D. Fatkin, M.E. Christe, and O. Aristizabal Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene J Clin Invest 103 1999 147 153
    • (1999) J Clin Invest , vol.103 , pp. 147-153
    • Fatkin, D.1    Christe, M.E.2    Aristizabal, O.3
  • 7
    • 0029807438 scopus 로고    scopus 로고
    • Mice expressing mutant myosin heavy chains are a model for familial hypertrophic cardiomyopathy
    • K.L. Vikstrom, S.M. Factor, and L.A. Leinwand Mice expressing mutant myosin heavy chains are a model for familial hypertrophic cardiomyopathy Mol Med 2 1996 556 567
    • (1996) Mol Med , vol.2 , pp. 556-567
    • Vikstrom, K.L.1    Factor, S.M.2    Leinwand, L.A.3
  • 8
    • 0034999263 scopus 로고    scopus 로고
    • Progression from hypertrophic to dilated cardiomyopathy in mice that express a mutant myosin transgene
    • K. Freeman, C. Colon-Rivera, and C. Olsson Progression from hypertrophic to dilated cardiomyopathy in mice that express a mutant myosin transgene Am J Physiol Heart Circ Physiol 280 2001 H151 H159
    • (2001) Am J Physiol Heart Circ Physiol , vol.280 , pp. H151-H159
    • Freeman, K.1    Colon-Rivera, C.2    Olsson, C.3
  • 9
    • 0033386313 scopus 로고    scopus 로고
    • A transgenic rabbit model for human hypertrophic cardiomyopathy
    • A.J. Marian, Y. Wu, and D.S. Lim A transgenic rabbit model for human hypertrophic cardiomyopathy J Clin Invest 104 1999 1683 1692
    • (1999) J Clin Invest , vol.104 , pp. 1683-1692
    • Marian, A.J.1    Wu, Y.2    Lim, D.S.3
  • 10
    • 2342521939 scopus 로고    scopus 로고
    • Evolution of expression of cardiac phenotypes over a 4-year period in the beta-myosin heavy chain-Q403 transgenic rabbit model of human hypertrophic cardiomyopathy
    • S.F. Nagueh, S. Chen, and R. Patel Evolution of expression of cardiac phenotypes over a 4-year period in the beta-myosin heavy chain-Q403 transgenic rabbit model of human hypertrophic cardiomyopathy J Mol Cell Cardiol 36 2004 663 673
    • (2004) J Mol Cell Cardiol , vol.36 , pp. 663-673
    • Nagueh, S.F.1    Chen, S.2    Patel, R.3
  • 11
    • 0025608774 scopus 로고
    • Developmental regulation of myosin gene expression in mouse cardiac muscle
    • G.E. Lyons, S. Schiaffino, D. Sassoon, P. Barton, and M. Buckingham Developmental regulation of myosin gene expression in mouse cardiac muscle J Cell Biol 111 1990 2427 2436
    • (1990) J Cell Biol , vol.111 , pp. 2427-2436
    • Lyons, G.E.1    Schiaffino, S.2    Sassoon, D.3    Barton, P.4    Buckingham, M.5
  • 12
    • 84885676191 scopus 로고    scopus 로고
    • Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathy
    • J. Jiang, H. Wakimoto, J.G. Seidman, and C.E. Seidman Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathy Science 342 2013 111 114
    • (2013) Science , vol.342 , pp. 111-114
    • Jiang, J.1    Wakimoto, H.2    Seidman, J.G.3    Seidman, C.E.4
  • 13
    • 0029816480 scopus 로고    scopus 로고
    • Conditional transgene expression in the heart
    • Z. Yu, C. Redfern, and G. Fishman Conditional transgene expression in the heart Circ Res 79 1996 691 697
    • (1996) Circ Res , vol.79 , pp. 691-697
    • Yu, Z.1    Redfern, C.2    Fishman, G.3
  • 14
    • 1042279539 scopus 로고    scopus 로고
    • Morphological and functional alterations in ventricular myocytes from male transgenic mice with hypertrophic cardiomyopathy
    • M.C. Olsson, B.M. Palmer, B.L. Stauffer, L.A. Leinwand, and R.L. Moore Morphological and functional alterations in ventricular myocytes from male transgenic mice with hypertrophic cardiomyopathy Circ Res 94 2004 201 207
    • (2004) Circ Res , vol.94 , pp. 201-207
    • Olsson, M.C.1    Palmer, B.M.2    Stauffer, B.L.3    Leinwand, L.A.4    Moore, R.L.5
  • 15
    • 33747072098 scopus 로고    scopus 로고
    • Prevalence, clinical profile, and significance of left ventricular remodeling in the end-stage phase of hypertrophic cardiomyopathy
    • K.M. Harris, P. Spirito, and M.S. Maron Prevalence, clinical profile, and significance of left ventricular remodeling in the end-stage phase of hypertrophic cardiomyopathy Circulation 114 2006 216 225
    • (2006) Circulation , vol.114 , pp. 216-225
    • Harris, K.M.1    Spirito, P.2    Maron, M.S.3
  • 16
    • 41949129330 scopus 로고    scopus 로고
    • Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy
    • T. Tsoutsman, M. Kelly, and D.C. Ng Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy Circulation 117 2008 1820 1831
    • (2008) Circulation , vol.117 , pp. 1820-1831
    • Tsoutsman, T.1    Kelly, M.2    Ng, D.C.3
  • 17
    • 25144511345 scopus 로고    scopus 로고
    • Cardiac transgenesis with the tetracycline transactivator changes myocardial function and gene expression
    • D.T. McCloskey, L. Turnbull, and P.M. Swigart Cardiac transgenesis with the tetracycline transactivator changes myocardial function and gene expression Physiol Genomics 22 2005 118 126
    • (2005) Physiol Genomics , vol.22 , pp. 118-126
    • McCloskey, D.T.1    Turnbull, L.2    Swigart, P.M.3
  • 18
    • 84855857750 scopus 로고    scopus 로고
    • Cardiac-specific expression of the tetracycline transactivator confers increased heart function and survival following ischemia reperfusion injury
    • L. Elsherif, X. Wang, M. Grachoff, B.M. Wolska, D.L. Geenen, and J.P. O'Bryan Cardiac-specific expression of the tetracycline transactivator confers increased heart function and survival following ischemia reperfusion injury PLoS One 7 2012 e30129
    • (2012) PLoS One , vol.7 , pp. e30129
    • Elsherif, L.1    Wang, X.2    Grachoff, M.3    Wolska, B.M.4    Geenen, D.L.5    O'Bryan, J.P.6
  • 19
    • 0024426784 scopus 로고
    • Mapping a gene for familial hypertrophic cardiomyopathy to chromosome 14q1
    • J.A. Jarcho, W. McKenna, and J.A. Pare Mapping a gene for familial hypertrophic cardiomyopathy to chromosome 14q1 N Engl J Med 321 1989 1372 1378
    • (1989) N Engl J Med , vol.321 , pp. 1372-1378
    • Jarcho, J.A.1    McKenna, W.2    Pare, J.A.3
  • 20
    • 0037173015 scopus 로고    scopus 로고
    • Assessment of diastolic function with Doppler tissue imaging to predict genotype in preclinical hypertrophic cardiomyopathy
    • C.Y. Ho, N.K. Sweitzer, and B. McDonough Assessment of diastolic function with Doppler tissue imaging to predict genotype in preclinical hypertrophic cardiomyopathy Circulation 105 2002 2992 2997
    • (2002) Circulation , vol.105 , pp. 2992-2997
    • Ho, C.Y.1    Sweitzer, N.K.2    McDonough, B.3
  • 21
    • 0034646743 scopus 로고    scopus 로고
    • Single-molecule mechanics of R403Q cardiac myosin isolated from the mouse model of familial hypertrophic cardiomyopathy
    • M.J. Tyska, E. Hayes, M. Giewat, C.E. Seidman, J.G. Seidman, and D.M. Warshaw Single-molecule mechanics of R403Q cardiac myosin isolated from the mouse model of familial hypertrophic cardiomyopathy Circ Res 86 2000 737 744
    • (2000) Circ Res , vol.86 , pp. 737-744
    • Tyska, M.J.1    Hayes, E.2    Giewat, M.3    Seidman, C.E.4    Seidman, J.G.5    Warshaw, D.M.6
  • 22
    • 84862673626 scopus 로고    scopus 로고
    • Cell-intrinsic functional effects of the α-cardiac myosin Arg403Gln mutation in familial hypertrophic cardiomyopathy
    • P. Chuan, S. Sivaramakrishnan, E.A. Ashley, and J.A. Spudich Cell-intrinsic functional effects of the α-cardiac myosin Arg403Gln mutation in familial hypertrophic cardiomyopathy Biophys J 102 2012 2782 2790
    • (2012) Biophys J , vol.102 , pp. 2782-2790
    • Chuan, P.1    Sivaramakrishnan, S.2    Ashley, E.A.3    Spudich, J.A.4
  • 23
    • 0036117921 scopus 로고    scopus 로고
    • The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model
    • C. Semsarian, I. Ahmad, and M. Giewat The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model J Clin Invest 109 2002 1013 1020
    • (2002) J Clin Invest , vol.109 , pp. 1013-1020
    • Semsarian, C.1    Ahmad, I.2    Giewat, M.3
  • 24
    • 0035902491 scopus 로고    scopus 로고
    • Simvastatin induces regression of cardiac hypertrophy and fibrosis and improves cardiac function in a transgenic rabbit model of human hypertrophic cardiomyopathy
    • R. Patel, S.F. Nagueh, and N. Tsybouleva Simvastatin induces regression of cardiac hypertrophy and fibrosis and improves cardiac function in a transgenic rabbit model of human hypertrophic cardiomyopathy Circulation 104 2001 317 324
    • (2001) Circulation , vol.104 , pp. 317-324
    • Patel, R.1    Nagueh, S.F.2    Tsybouleva, N.3
  • 25
    • 23344440434 scopus 로고    scopus 로고
    • Prevention of cardiac hypertrophy by atorvastatin in a transgenic rabbit model of human hypertrophic cardiomyopathy
    • V. Senthil, S.N. Chen, and N. Tsybouleva Prevention of cardiac hypertrophy by atorvastatin in a transgenic rabbit model of human hypertrophic cardiomyopathy Circ Res 97 2005 285 292
    • (2005) Circ Res , vol.97 , pp. 285-292
    • Senthil, V.1    Chen, S.N.2    Tsybouleva, N.3
  • 26
    • 64549096033 scopus 로고    scopus 로고
    • Resolution of established cardiac hypertrophy and fibrosis and prevention of systolic dysfunction in a transgenic rabbit model of human cardiomyopathy through thiol-sensitive mechanisms
    • R. Lombardi, G. Rodriguez, and S.N. Chen Resolution of established cardiac hypertrophy and fibrosis and prevention of systolic dysfunction in a transgenic rabbit model of human cardiomyopathy through thiol-sensitive mechanisms Circulation 119 2009 1398 1407
    • (2009) Circulation , vol.119 , pp. 1398-1407
    • Lombardi, R.1    Rodriguez, G.2    Chen, S.N.3
  • 27
    • 33645282296 scopus 로고    scopus 로고
    • Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy
    • J.P. Konhilas, P.A. Watson, and A. Maass Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy Circ Res 98 2006 540 548
    • (2006) Circ Res , vol.98 , pp. 540-548
    • Konhilas, J.P.1    Watson, P.A.2    Maass, A.3
  • 28
    • 84896509481 scopus 로고    scopus 로고
    • Hypertrophic and dilated cardiomyopathy: Four decades of basic research on muscle lead to potential therapeutic approaches to these devastating genetic disorders
    • J.A. Spudich Hypertrophic and dilated cardiomyopathy: four decades of basic research on muscle lead to potential therapeutic approaches to these devastating genetic disorders Biophys J 206 2014 1236 1249
    • (2014) Biophys J , vol.206 , pp. 1236-1249
    • Spudich, J.A.1
  • 29
    • 0017286948 scopus 로고
    • Coordinated synthesis and degradation of actin and myosin in a variety of myogenic and non-myogenic cells
    • N. Rubinstein, J. Chi, and H. Holtzer Coordinated synthesis and degradation of actin and myosin in a variety of myogenic and non-myogenic cells Exp Cell Res 97 1976 387 393
    • (1976) Exp Cell Res , vol.97 , pp. 387-393
    • Rubinstein, N.1    Chi, J.2    Holtzer, H.3
  • 30
    • 0015799124 scopus 로고
    • Studies on the synthesis and degradation of light and heavy chains of cardiac myosin
    • J. Wikman-Coffelt, R. Zelis, C. Fenner, and D.T. Mason Studies on the synthesis and degradation of light and heavy chains of cardiac myosin J Biol Chem 248 1973 5206 5207
    • (1973) J Biol Chem , vol.248 , pp. 5206-5207
    • Wikman-Coffelt, J.1    Zelis, R.2    Fenner, C.3    Mason, D.T.4
  • 31
    • 0025727160 scopus 로고
    • Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart
    • W.A. Ng, I.L. Grupp, A. Subramaniam, and J. Robbins Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart Circ Res 68 1991 1742 1750
    • (1991) Circ Res , vol.68 , pp. 1742-1750
    • Ng, W.A.1    Grupp, I.L.2    Subramaniam, A.3    Robbins, J.4
  • 32
    • 0022498091 scopus 로고
    • Development and progression of left ventricular hypertrophy in children with hypertrophic cardiomyopathy
    • B.J. Maron, P. Spirito, Y. Wesley, and J. Arce Development and progression of left ventricular hypertrophy in children with hypertrophic cardiomyopathy N Engl J Med 315 1986 610 614
    • (1986) N Engl J Med , vol.315 , pp. 610-614
    • Maron, B.J.1    Spirito, P.2    Wesley, Y.3    Arce, J.4
  • 33
    • 0035017153 scopus 로고    scopus 로고
    • Human cardiac myosin heavy chain isoforms in fetal and failing adult atria and ventricles
    • P.J. Reiser, M.A. Portman, X.H. Ning, and C.S. Moravec Human cardiac myosin heavy chain isoforms in fetal and failing adult atria and ventricles Am J Physiol Heart Circ Physiol 280 2001 H1814 H1820
    • (2001) Am J Physiol Heart Circ Physiol , vol.280 , pp. H1814-H1820
    • Reiser, P.J.1    Portman, M.A.2    Ning, X.H.3    Moravec, C.S.4
  • 34
    • 84900331122 scopus 로고    scopus 로고
    • A proliferative burst during pre-adolescence establishes the final cardiomyocyte number
    • N. Naqvi, M. Li, and J.W. Calvert A proliferative burst during pre-adolescence establishes the final cardiomyocyte number Cell 157 2014 795 807
    • (2014) Cell , vol.157 , pp. 795-807
    • Naqvi, N.1    Li, M.2    Calvert, J.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.