Targeted delivery via avidin fusion protein: Intracellular fate of biotinylated doxorubicin derivative and cellular uptake kinetics and biodistribution of biotinylated liposomes

European Journal of Pharmaceutical Sciences

Volumn 47, Issue 5, 2012, Pages 848-856

  Soininen, Suvi K ^a   Lehtolainen Dalkilic, Pauliina ^c   Karppinen, Tanja ^a   Puustinen, Tiina ^a   Dragneva, Galina ^a   Kaikkonen, Minna U ^a,c   Jauhiainen, Marjo ^a   Allart, Brigitte ^d   Selwood, David L ^d   Wirth, Thomas ^a   Lesch, Hanna P ^a,c   Määttä, Ann Marie ^c   Mönkkönen, Jukka ^a   Ylä Herttuala, Seppo ^a,b   Ruponen, Marika ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

^c Finland Ark Therapeutics Oy   (Finland)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Active targeting; Avidin; Biotin; Doxorubicin; Liposomes

Indexed keywords

AVIDIN; DOXORUBICIN DERIVATIVE; LENTIVIRUS VECTOR; LIPOSOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOTINYLATION; CELL MEMBRANE; CELL NUCLEUS; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG TARGETING; GLIOMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KINETICS; MASS SPECTROMETRY; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; AVIDIN; BIOTIN; BIOTINYLATION; CELL LINE, TUMOR; DOXORUBICIN; HUMANS; KINETICS; LIPOSOMES; MICE; MICE, NUDE; RATS; RECOMBINANT FUSION PROTEINS; TISSUE DISTRIBUTION;

EID: 84868709719     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.09.001     Document Type: Article

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