Synaptic synthesis, dephosphorylation, and degradation: A novel paradigm for an activity-dependent neuronal control of CDKL5

Journal of Biological Chemistry

Volumn 290, Issue 7, 2015, Pages 4512-4527

  La Montanara, Paolo ^a   Rusconi, Laura ^a   Locarno, Albina ^a   Forti, Lia ^a   Barbiero, Isabella ^a   Tramarin, Marco ^a   Chandola, Chetan ^a   Kilstrup Nielsen, Charlotte ^a   Landsberger, Nicoletta ^a,b  

^a UNIVERSITY OF INSUBRIA   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGY;

ACTIVITY-DEPENDENT; DEPHOSPHORYLATIONS; INTELLECTUAL DISABILITY; LOCAL SYNTHESIS; NEURONAL ACTIVATION; NEURONAL ACTIVITIES; NEURONAL CONTROL;

NEURONS;

CELL PROTEIN; CYCLIN DEPENDENT KINASE LIKE 5; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHOSPHOPROTEIN PHOSPHATASE 1; UNCLASSIFIED DRUG; CDKL5 PROTEIN, MOUSE; MESSENGER RNA; PROTEASOME; PROTEIN SERINE THREONINE KINASE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL MATURATION; CELL VIABILITY; CONTROLLED STUDY; EMBRYO; FEMALE; MOUSE; NERVE CELL; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE CELL PLASTICITY; NONHUMAN; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; RNA TRANSLATION; SIGNAL TRANSDUCTION; YOUNG ADULT; ANIMAL; APOPTOSIS; BRAIN CORTEX; CELL CULTURE; CYTOLOGY; ELECTROPHYSIOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HIPPOCAMPUS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYNAPSE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELLS, CULTURED; CEREBRAL CORTEX; ELECTROPHYSIOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; HIPPOCAMPUS; MICE; NEURONS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BIOSYNTHESIS; PROTEIN PHOSPHATASE 1; PROTEIN-SERINE-THREONINE KINASES; PROTEOLYSIS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, N-METHYL-D-ASPARTATE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 84922812800     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.589762     Document Type: Article

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