Extrasynaptic N-Methyl-D-aspartate (NMDA) receptor stimulation induces cytoplasmic translocation of the CDKL5 kinase and its proteasomal degradation

Journal of Biological Chemistry

Volumn 286, Issue 42, 2011, Pages 36550-36558

  Rusconi, Laura ^a   Kilstrup Nielsen, Charlotte ^a   Landsbergers, Nicoletta ^a,b  

^a UNIVERSITY OF INSUBRIA   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DEVELOPMENT; CELL-DEATH PATHWAYS; DEVELOPMENTAL DELAY; HIPPOCAMPAL NEURONS; HYDROGEN PEROXIDE TREATMENT; N METHYL D ASPARTATE RECEPTOR; N-METHYL-D-ASPARTATE; NEUROTROPHIC FACTORS; PROLIFERATING CELLS; PROTEASOMAL DEGRADATION; RECEPTOR STIMULATION; SUBCELLULAR LOCALIZATIONS; X-LINKED GENES;

CELL DEATH; CELL PROLIFERATION; DEGRADATION; GENES; HYDROGEN PEROXIDE; LAKES;

ENZYMES;

CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE LIKE 5; GLUTAMIC ACID; HYDROGEN PEROXIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROTROPHIC FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CELL DEATH; CELL NUCLEUS; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; EMBRYO; ENZYME DEGRADATION; ENZYME LOCALIZATION; HIPPOCAMPUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEASOMAL DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL NUCLEUS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTAMIC ACID; HIPPOCAMPUS; HUMANS; MICE; NEURONS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, N-METHYL-D-ASPARTATE;

MURINAE;

EID: 80054684531     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.235630     Document Type: Article

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