Mapping pathological phenotypes in a mouse model of CDKL5 disorder

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Amendola, Elena ^a   Zhan, Yang ^a   Mattucci, Camilla ^a   Castroflorio, Enrico ^b   Calcagno, Eleonora ^b   Fuchs, Claudia ^c   Lonetti, Giuseppina ^d,e   Silingardi, Davide ^d   Vyssotski, Alexei L ^f   Farley, Dominika ^a   Ciani, Elisabetta ^c   Pizzorusso, Tommaso ^d,e   Giustetto, Maurizio ^b   Gross, Cornelius T ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY EMBL   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d CNR   (Italy)

^e UNIVERSITY OF FLORENCE   (Italy)

^f Institute of Neuroinformatics Zurich   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DISEASE; CONTROLLED STUDY; CYCLIN DEPENDENT KINASE LIKE 5 GENE; DENDRITE; ELECTROENCEPHALOGRAM; EPILEPSY; EPILEPTIC ENCEPHALOPATHY; EVOKED VISUAL RESPONSE; EYE TRACKING; FEMALE; FOREBRAIN; GENE; HAND MOVEMENT; HYPOACTIVITY; KNOCKOUT MOUSE; MALE; MOUSE; MOUSE MODEL; MUSCLE HYPOTONIA; NONHUMAN; SEIZURE; ANALYSIS OF VARIANCE; ANIMAL; DISEASE MODEL; ELECTROENCEPHALOGRAPHY; EYE MOVEMENT; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; IMMUNOHISTOCHEMISTRY; INFANTILE SPASM; NONPARAMETRIC TEST; PATHOLOGY; PHENOTYPE; PHYSIOLOGY; RETT SYNDROME; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

CDKL5 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; DENDRITES; DISEASE MODELS, ANIMAL; ELECTROENCEPHALOGRAPHY; EVOKED POTENTIALS, VISUAL; EYE MOVEMENTS; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOHISTOCHEMISTRY; MICE; MICE, KNOCKOUT; PHENOTYPE; PROSENCEPHALON; PROTEIN-SERINE-THREONINE KINASES; RETT SYNDROME; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPASMS, INFANTILE; STATISTICS, NONPARAMETRIC;

EID: 84901371875     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091613     Document Type: Article

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